β and mitochondrial dysfunction in down s syndrome
Báo cáo y học: " Gene expression variation in Down''''s syndrome mice allows prioritization of candidate genes" potx
... expressionsmiceTs65DnandelecReferencesPavaluesintensitieslistingelectronicintensitiesdeviations AdditionaltableBiosystems)andrepresentvariance,test, brainmice in pools,tissues summary brain line).from ... by examining pooled RNAs in multiple tissues from several individuals in independent analyses [18,19] In the present study we also assessed Ts65Dn/euploid gene expression ratios in pools and corroborated ... previous findings using pooled samples; specifically, most trisomic genes exhibit an increased transcript level that is about 50% higher than in euploid across tissues Several specific instances of...
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Báo cáo y học: "Abnormalities of B cell phenotype, immunoglobulin gene expression and the emergence of autoimmunity in Sjögren’s syndrome" pdf
... immunopathogenesis Cytokines Several cytokines have been demonstrated in inflamed tissue by using reverse-transcriptase-mediated polymerase chain reaction technologies as well as in animal models Cytokines, ... found to be expressed in these cells On the basis of the available data on the distribution of B cell subsets in SLE versus pSS, there is increasing evidence that diseases associated with immunologic ... European Study Group on Classification Criteria for Sjögren s Syndrome Assessment of the European classification criteria for Sjögren s syndrome in a series of clinically defined cases: results of...
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Báo cáo khoa học: "Tongue carcinoma in an adult Down''''s syndrome patient: a case report" potx
... purposes) World Journal of Surgical Oncology 2009, 7:26 ting other kinds of cancer [3] In a study of 2421 children with DS in Massachusetts, no cases of solid tumors were observed [4] In another study ... which suggests that this rare type of solid tumors in DS patients may take an aggressive course This unique case might not be sufficient to make a significant conclusion on the prognosis and survival ... tracheostomy and a gastrostomy performed months after the diagnosis of recurrence The patient died one month later, months after the initial diagnosis Discussion Down' s syndrome or trisomy 21 is characterized...
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Báo cáo y học: "B cells in Sjögren’s syndrome: indications for disturbed selection and differentiation in ectopic lymphoid tissue" doc
... data on the distribution of B-cell subsets in chronic inflammatory rheumatic diseases, such as pSS, RA and SLE, and in infectious diseases, there is increasing evidence that diseases associated with ... structures in a single biopsy reflects a snapshot of a slowly progressive inflammatory disease, pSS, or a subpopulation of patients with a more severe disease and/ or a distinct immune response ... expressing particular VL genes within the ectopic lymphoid tissue in pSS [24,79,80] In accord with these results, earlier studies examining idiotype expression by glandular B cells in pSS have also...
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Báo cáo y học: "Biomarker profiles in serum and saliva of experimental Sjögren''''s syndrome: associations with specific autoimmune manifestations" ppt
... regarding 87 analytes in serum and 75 proteins in saliva Thirty and 62 of these molecules have not yet been investigated in SS patients and SS-like disease in NOD mice, respectively Thirty-six and ... organs were fixed in 4% formalin before embedding in paraffin, sectioning, and staining with haematoxylin and eosin Sections obtained from the kidneys were also stained using the periodic acid-Schiff ... (Supplementary table 1) Few studies have assessed interactions between several immune molecules and their association with disease parameters Summarizing findings regarding immune mediators such...
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Báo cáo y học: "Primary prevention of Down’s syndrome"
... findings in Down syndrome, England and Wales 1989 to 1993 J Med Genet 1996;33:387-394 Cuckle HS, Wald NJ, Thompson SC Estimating a women 's risk of having a pregnancy associated with Down' s syndrome ... 70(4):495-501 Hobbs CA, Sherman SL, Yi P, Hopkins SE, Torfs CP, Hine RJ, Pogribna M, Rozen R, James SJ Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome Am ... S, Senior B, Spencer K, Standing S Age-standardisation for monitoring performance in Down s syndrome screening programmes Prenat Diagn 2004;24(11):851-856 25 Stene E, Stene J, Stengel-Rutkowski...
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Relationship between stock return and trading volume in vietnam's stock market
... I(0) I(0) I(0) Cointegrat ion at 1% Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes 44 Table A4 ... traded stocks In short, the finding of this dissertation less supports to the mixture distribution hypothesis but it is consistent with previous studies on this issue in emerging markets 5.2 IMPLICATIONS ... management and supervising system on the public information disclosures to get a fair markets for investors On another hand, the inference from this paper is useful for investors‟ consideration in making...
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Tài liệu The Centrality of Money, Credit, and Financial Intermediation in Marx’s Crisis Theory: An Interpretation of Marx’s Methodology pptx
... rates of interest Vigorous capital investment will initially increase profits; in turn, sustained high profits will serve to increase confidence and improve the business climate.48 Assessments ... general possibility of crisis is given in the process of metamorphosis of capital itself, and in two ways: in so far as money functions as means of circulation, [the possibility of crisis lies in] ... credit system comes under duress, confidence shatters, interest rates soar, risk-aversion rises dramatically and the forced sale of real and financial assets caused by a desperate effort to obtain...
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Tài liệu Social and working conditions in Asia’s rubber plantations & CS policies and practices of rubber gloves, boots, mattresses and condoms brands in Denmark docx
... gloves brands and rubber boots brands in Denmark Malaysia, Thailand, Vietnam and Indonesia show up the most For car tires and bike tires, Indonesia shows up most times For hospital gloves, Malaysia ... countries such as Thailand, Indonesia and Malaysia as well as in consuming countries such as China, India, USA and the EU Regarding the main producing countries, Thailand and Malaysia have more, and ... companies adress CSR in their supply chains: - None of the companies were found to include at rubber producers, such as plantation estates, in their CSR policies - Coop and CChansen adress CSR issues...
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An Unbreakable Cycle - Drug Dependency Treatment, Mandatory Confinement, And HIV/AIDS In China''''s Guangxi Province potx
... targeting drug users China s 1998-2010 Strategic Plan included specific goals to expand programs targeting drug users both in community settings and in detox and RTL centers China s response to ... drug dependency in China, and drug users face increasingly severe sentences for drug possession or use These sentences are imposed administratively, with little recourse to the courts or fundamental ... patients, drug users are treated as criminals and subject to physical, psychological, and sexual abuse; forced labor; and inhumane living conditions In the past five years, attention to drug users and...
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Zero Interest Rates and the Fall in U.S. Bank Lending pdf
... reflecting an offsetting large fall in the base money multiplier Most disappointing of all, figure also shows that retail bank lending declined and continues to decline so far in 2009 Insofar as U .S ... Now suppose some upsetting event, such as a crash in home prices makes all mortgage related assets on bank balance sheets suspect Then counter party risk becomes acute, and banks become less willing ... complex subject, I will discuss just the first— and the least self-evident of the three points Wholesale Interbank Markets: Counterparty Risk and Zero Short-Term Interest Rates In the current crisis,...
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Báo cáo khoa học: Lithium increases PGC-1a expression and mitochondrial biogenesis in primary bovine aortic endothelial cells ppt
... various substances and factors in brain, heart and vessel ischemic–reperfusion injuries also seem to be mediated in part by an increase in mitochondrial biogenesis and preservation of mitochondrial ... Under physiological conditions, changes in mitochondrial biogenesis and mass within cells and tissues reflect changes in energy demand and hormonal status, and depend mainly on changes in the activity ... characteristic of many neurodegenerative diseases such as Alzheimer s and Parkinson s [28], and has also been seen in postmortem brain biopsies from subjects with bipolar disorder [29] Mutated huntingtin...
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Psychiatric and Cognitive Disorders in Parkinson’s Disease pptx
... guidelines, case studies and rating scales will meet the needs of all clinicians working with Parkinson s disease patients Sergio E Starkstein was Assistant Professor of Psychiatry at Johns Hopkins ... Epidemiologic, clinical, and therapeutic aspects of Parkinson s disease Parkinsonism and Parkinson s disease 34 Cognitive deficits in Parkinson s disease 55 Depression in Parkinson s disease 88 Anxiety, ... the disease itself This subject is further discussed in chapter Clusters of parkinsonian signs and subgroups of the disease A question now arising is whether PD constitutes one single and clinically...
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Striking First - Preemptive and Preventive Attack in U.S. National Security Policy pdf
... better than initiating it; for the United States, the Cuban missile crisis was such a case The second class of difficult cases arises when states possess large first-strike advantages, but are significantly ... ambiguous terms, and the National Security Strategy does not even raise the possibility of striking first against targets other than terrorists or hard-to-deter states possessing or pursuing weapons ... The 2002 NSS s statements regarding striking first are excerpted in their entirety in Appendix D A revised NSS, released in 2006, discussed striking first less extensively, but states, “The place...
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an introduction to programming and numerical methods in matlab - s.r. otto & j.p. denier
... commands, input and num2str The input command prompts the user with the flag contained within the quotes ’ ’ and takes the user s response from the standard input, in this case the MATLAB window In ... (cosine) and tan (tangent) (with their inverses being obtained by appending an a as in asin, acos or atan) These functions take an argument in radians, and the result of the inverse functions is ... 1.2 Scalar Quantities and Variables 11 message, in this case ??? Undefined function or variable ’xsin’ In cases such as these MATLAB provides useful information as to where we have gone wrong; information...
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Báo cáo hóa học: " Immune and hemorheological changes in Chronic Fatigue Syndrome" pdf
... phenotypes To assess the levels of NK phenotypes in CFS patients and healthy controls, NK lymphocytes were isolated from whole blood according to manufacturer s instructions using RosetteSep Human ... analysis Plasma fibrinogen was assessed by the CLAUSS method [25] using a STA-Compact analyser (Diagnostica Page of 10 Stago, Asnieres, France) where the intra-assay coefficient of variation was ... invasion and lysis High levels of TFG-b also cause an increase in neutrophil apoptosis and this occurs in some cases of CFS [11] Finally viral-specific Brenu et al Journal of Translational Medicine...
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báo cáo sinh học:" Workplace violence and gender discrimination in Rwanda’s health workforce: Increasing safety and gender equality" ppt
... women s opinion, and the role of harshness and violence in controlling women s behavior [18] Violence against women in Rwanda seems to have been enshrined in traditional sayings and buttressed ... violence In most cases–especially those of verbal abuse, bullying, and physical violence–subjects disclosed the incident to colleagues, friends and family However, in 40% of sexual harassment cases, ... research and workforce assessments should routinely measure the extent of systemic gender discrimination at work Second, eliminating gender inequality, bias, and specific forms of discrimination should...
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Khóa luận tốt nghiệp tiếng anh: A Study on the relationship between service quality and customer satisfaction in Hanoi’s tourism
... between suppliers and customers This also has positive effect to customer loyalty and profitability When suppliers meet customers’ needs, desires and requests, resulting in the increasing of customer ... questionnaire consists of independent parts including measurement scales designed to assess the constructs of this study and demographic information Demographic Variables 29 In the first section ... trustworthiness, and reliability of hotel staff and local people 4) Fairness of price: the fairness of products’ cost at tourist spots and shops as well as local conveyances 5) Hygiene: the cleanliness...
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Báo cáo khoa học: "Drought susceptibility and xylem dysfunction in seedlings of 4 European oak species" pdf
... range in drought susceptibility In this research, drought susceptibility was compared in potted seedlings of the species using the techniques of acoustic emission and hydraulic conductivity It is ... from stem tissues on 31 May then on the previous day, but fewer vessels were producing AEs in response DISCUSSION It is important to know whether drought susceptibility is inherent at the seedling ... discernible differences between seedlings grown from seed or bought in root trainers Each point is the mean of determinations for petioles Lines were fitted by linear regression using the transformed...
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