... that aortic distensibility is not impaired in patients with different forms of Chagas' disease, even in those with heart failure Our results observed in patients without CHF coincide with those ... impaired in group that comprised patients with systolic dysfunction Also, the peak VO2 was significantly decreased in group patients with systolic dysfunction, in comparison with that in patients without ... infiltrates and focus of myocarditis associated with focal fibrosis, with a variable intensity Experimentally, Chagas' disease causes vasculitis of the large arteries, affecting the muscular and endothelial...
Ngày tải lên: 11/08/2014, 08:20
... severe sepsis, in children with severe sepsis, and in patients receiving lowdose heparin [3] In the Administration of Drotrecogin Alfa (Activated) in Early Stage Severe Sepsis (ADDRESS) study [1], ... time to treatment with DrotAA has an influence on mortality [9,10], with the maximum beneficial effect being observed if treatment is started within 24 hours of the onset of sepsis-induced organ ... lung injury/acute respiratory distress syndrome Recommendation We concur with the ADDRESS authors DrotAA should not be used in patients with severe sepsis and low risk for death Competing interests...
Ngày tải lên: 13/08/2014, 03:20
Pulmonary Tuberculosis in Patients with HIV/AIDS in Iran pptx
... 16(SPSS Inc., Chicago, IL) Imam hospital is the main referral teaching hospital for HIV/ AIDS patients in Iran The records of all patients with TB /HIV co-infection admitted to the Infectious Disease ... seropositivity was confirmed by at least two positive ELISA tests followed by a positive western blot test as confirmations In HIV positive patients, tuberculin skin test ≥ mm and in HIV negative patients, ... or in other words, in those with high CD4 cell count Those with CD4 count less than 200, mostly show atypical CXR findings In addition, normal and traditional typical findings of tuberculosis...
Ngày tải lên: 22/03/2014, 18:20
Báo cáo y học: " Decrease of vitamin D concentration in patients with HIV infection on a non nucleoside reverse transcriptase inhibitor-containing regimen" doc
... boosted regimen with Ritonavir Twenty-seven individuals were taking Tenofovir; 18 in combination with NNRTIs and with PIs Patients taking corticosteroids, suffering from Laboratory analysis Plasma ... bioavailability of vitamin D in obesity Am J Clin Nutr 2000, 72:690-693 Page of 38 Bischoff-Ferrari H: Health effects of vitamin D Dermatol Ther 2010, 23:23-30 39 Glare PA: Pain in patients with HIV infection: ... D: Greater decrease in bone mineral density with protease inhibitor regimens compared with nonnucleoside reverse transcriptase inhibitor regimens in HIV- 1 infected naive patients AIDS 2009, 27:817-824...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Downregulation of CD94/NKG2A inhibitory receptors on cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts" doc
... from HIV- 1 infected patients, and its relationship with HIV- 1 viraemia Immunostaining was performed with fluorochrome-conjugated antibodies in 100 μl of peripheral blood from HIV- 1 infected patients ... NK cells bearing the CD94/NKG2A inhibitory receptor decreases in advanced HIV infection [8], in contrast with other inhibitory receptors of the KIR family which are upregulated It is presently ... and HIV- 1 infected controls (viraemic and aviraemic) There was a dramatic decline in the proportion of CD8+ T cells expressing the CD94/NKG2A heterodimer in HIVinfected patients in comparison with...
Ngày tải lên: 13/08/2014, 05:22
Báo cáo y học: "Host immune response in sepsis due to ventilator-associated pneumonia: how is it different" pot
... Critical Care Vol 13 No Christaki implications of endotoxin tolerance continue to be elusive [4] Although endotoxin tolerance has been implicated in increased susceptibility to secondary infections, ... underlying dysregulations that contribute to the pathogenesis of VAP Although patients in the two groups did not differ significantly in terms of age, disease severity, underlying conditions, ... Raftogiannis M, Zervakis D, Koussoulas V, Orfanos S, Kotanidou A, Armaganidis A, Roussos C, Giamarellou H: Early apoptosis of blood monocytes in the septic host: is it a mechanism of protection in the...
Ngày tải lên: 13/08/2014, 20:21
Báo cáo y học: "Effect of methotrexate and anti-TNF on Epstein-Barr virus T-cell response and viral load in patients with rheumatoid arthritis or spondylarthropathies" ppt
... treatment with methotrexate or tumor necrosis factor alpha inhibitors does not increase Epstein-Barr virus load in patients with rheumatoid arthritis Arthritis Rheum 2007, 57:762-767 Smets F, Latinne ... Kennedy LG, Whitelock H, Gaisford P, Calin A: A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index J Rheumatol 1994, 21:2286-2291 ... viral load and disease activity (Disease Activity Score for 28 joints for RA patients, P = 0.54; Bath Ankylosing Spondylitis Disease Activity Index for SpA patients, P = 0.84) or disease duration...
Ngày tải lên: 09/08/2014, 14:21
Báo cáo y học: "Protein-losing enteropathy in patients with Fontan circulation: is it triggered by infection" ppt
... system during the early development of PLE, rather than a causal factor However, reports of opportunistic infections in patients with PLE are rare [5,10] This finding is in agreement with our observation ... albumin, × 50 ml 20%/day), a single immunglobulin infusion (Sandoglobin®), C1-esterase-inhibitor (Berinert®) and prednisolon (3 × mg/day per orally; during the early phase, in addition, 10–20 mg intravenously) ... been missed on the biopsies, as proposed by others [3] 190 Finally, is an ‘infection hypothesis’ plausible for the development of PLE in Fontan patients? We speculate that it is All patients with...
Ngày tải lên: 12/08/2014, 19:22
Báo cáo y học: "Correction: Protein-losing enteropathy in patients with Fontan circulation: is it triggered by infection" pptx
Ngày tải lên: 12/08/2014, 19:22
Báo cáo khoa học: "Clinical review: How is risk defined in high-risk surgical patient management" ppt
... hours with or without operation 93.3 E Emergency operation because it is simple to calculate without requiring additional resources It may be surprising that it is predictive, as ASA scoring does ... assessing risk, there is a paucity of clinical studies showing how this has changed the management of either individual patients or groups of patients We hope that soon data will appear showing how ... possibilities of influencing change and costs It is also interesting to compare the presented definitions with the various studies of ‘high risk’ surgical patients where different levels of risk...
Ngày tải lên: 12/08/2014, 22:21
Báo cáo y học: "Medical emergency motorcycle – is it useful in a Scandinavian Emergency Medical Service?" docx
... MEM in Portugal with emphasis on its efficiency in reducing response times and in evaluating patients where the need for immediate assistance was uncertain [4] One serious injury and two minor injuries ... MEM was not used after 10 PM in order to reduce the accident risk No injuries to the MEM paramedic were registered and this is in accordance with Portuguese results indicating 0.8 injuries pr ... medical interventions in 121 patients before the arrival of another ambulance Intravenous drugs were given in 63 cases, including 23 cases of naloxone administration to heroine intoxicated patients...
Ngày tải lên: 13/08/2014, 23:20
báo cáo hóa học: " Is global quality of life reduced before fracture in patients with low-energy wrist or hip fracture? A comparison with matched controls" docx
... health-focused quality of life even before the fracture occur [29-32] The wrist patients have a modest decrease in health-focused quality of life within physical domain and scores in accordance with ... diseases and conditions as well [56] However, our findings suggest that by identifying patients with low GQOL, in addition to other known risk factors for hip fracture, may rise the probability ... develop and initiate prevention and rehabilitation efforts Conclusion This is the first study to compare GQOL in patients with a low-energy wrist fracture or hip fracture with GQOL scores in matched...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer" docx
... Cell viability (%) A Without ascites With ascites * Without ascites With ascites * * * * * 10 TRAIL (ng/ml) 25 10 TRAIL (ng/ml) 25 Cell viability (%) 318A cells Without ascites With ascites * * ... prognosis potential of having protective ascites against TRAIL-induced CaOV3 cell death Protective ascites were arbitrarily defined as TRAIL IC50 with ascites/IC50 without ascites > 2-fold Clinical ... cancer ascites inhibit TRAIL- and FasL-induced apoptosis in vitro [10] In that study, six ovarian cancer ascites were tested and five out of six inhibited TRAIL-induced cell death, albeit to different...
Ngày tải lên: 20/06/2014, 07:20
Báo cáo y học: "The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus" potx
... patients with SLE as well as in 40% of patients with mixed connective tissue disease, usually in association with other anti-spliceosomal autoAbs [8,9] The autoAb response against hnRNP-A2 shows ... for this antigen The data obtained suggest that hnRNP-A2 may constitute an important T cell autoantigen in patients with SLE, indicating a potential role for it in the pathogenesis of this disorder ... cultures with antigen to mean cpm obtained in cultures incubated in the absence of antigen An SI ≥3.0 and a ∆cpm >1,000 (mean cpm obtained in cultures with antigen minus mean cpm obtained in cultures...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: " Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthriti" pdf
... fluid neutrophil apoptosis was significantly lower in patients with RA than in patients with non-RA persistent synovitis (P = 0.0004) or in patients with resolving synovitis (P = 0.002) Results ... than at initial presentation in two of the 10 RA patients, six of the 11 patients with non-RA persistent synovitis and four of the 11 patients with resolving synovitis Prior therapy with a DMARD ... than at initial presentation in two of the seven RA patients, four of the 11 patients with non-RA persistent synovitis, and seven of the 13 patients with resolving synovitis Prior therapy with a...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosu" pptx
... infection in our patients in the best multiple logistic regression model This finding is in line with a previous study on major infections in SLE patients in the Hopkins Lupus Cohort [32] Renal insufficiency ... deposition, and MBL pathway activity in three subgroups of patients: SLE patients with one or more major infections, patients with SLE who experienced minor infections only, and SLE patients without ... one infectious episode since lupus diagnosis in 50% of patients with SLE, and this high infection rate is confirmed by other studies reporting infectious complications in up to 45% of SLE patients...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis" doc
... overexpressed in inflamed synovial tissue, in particular in the lining layer and in sublining cells [9], and it is elevated in draining lymph from affected joints [10] Furthermore, IL-1β is localized ... time point during the study apy in RA in disease Reductionpatients activity and CRP levels following ACZ885 therapy in RA patients (a) Mean disease activity (Disease Activity Score using 28 joint ... binding of the two natural ligands, namely IL-1α and IL-1β As compared with TNF-α inhibitors, it appears that treatment with the recombinant IL-1Ra is less efficacious in RA [3] However, it is...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Rheumatoid cachexia is associated with dyslipidemia and low levels of atheroprotective natural antibodies against phosphorylcholine but not with dietary fat in patients with rheumatoid arthritis: a cross-sectional study" pdf
... leading to cachexia This finding is in accordance with the known difficulties of treating cachexia with diet However, recently supplements with amino acids have been shown to increase muscle mass ... this definition of rheumatoid cachexia to be used, as it verifies that it is associated with increased morbidity However, patients on a Mediterranean-like diet had high anti-PC levels in spite ... min), chronic obstructive lung disease with emphysema, earlier gastric ulcer or intestinal surgery, known eating disorder or steroid injections within weeks The patient characteristics are shown...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "Uric acid is a strong independent predictor of renal dysfunction in patients with rheumatoid arthritis" docx
... file) Insulin resistance was evaluated from fasting glucose and insulin using the Homeostasis Model Assessment of Insulin Resistance (HOMA IR) [30] and the Quantitative Insulin Sensitivity Check Index ... insulin resistance and chronic kidney disease in nondiabetic patients, independent of other risk factors [64] Insulin resistance has also been described in patients with RA and may associate with ... Nightingale P, Douglas KM, Kitas GD: Cardiovascular risk factors and not disease activity, severity or therapy associate with renal dysfunction in patients with rheumatoid arthritis Ann Rheum Dis...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: " Management of HIV-1 associated hepatitis in patients with acquired immunodeficiency syndrome: role of a successful control of viral replication" ppsx
... with Hepatotoxicity in an HIV- Infected Individual J Infect Dis 2008, 197:932-933 doi:10.1186/1742-6405-8-9 Cite this article as: Esposito et al.: Management of HIV- 1 associated hepatitis in patients ... this was observed in association with an immune recovery, suggesting the hypothesis of a pathogenetic role played by HIV- 1 infection in the liver damage In patients with HIV- 1 disease there are ... were predominantly within the normal ranges, with only small increases due to occasional alcohol intake On September 2006, during a rescue treatment with atazanavir/ ritonavir, lamivudine and tenofovir,...
Ngày tải lên: 10/08/2014, 05:22