nd the radius and region of convergence

... region Effect of mutations in the C-terminal region of the RmInt1 IEP on RNA splicing in vivo We constructed a series of mutants to identify the functional features of the C-terminal region of ... investigated the C-terminal region of the RmInt1 IEP up to the maturase domain and the C-tail We found that the C-tail and upstream amino acid residues, located in a predicted a-helical region, form ... important region of the IEP maturase domain that is conserved throughout the evolution in the D lineage We show that C-tail of the RmInt1 IEP contributes to the maturase function of this RT protein and...

Ngày tải lên: 15/03/2014, 09:20

... part of the coenzyme B-binding site Its unmethylated nitrogen atom Ne2 donates the shortest of the three hydrogen bonds of the protein to the phosphate group of coenzyme B The distance of ˚ 2.65 ... because the genes required for the biosynthesis of the nickel cofactor F430 [16] and for the post-translational modifications [9] are not yet known [17,18] Also, the in vitro reconstitution of active ... or 2-methylglutamine The methylated histidine (H257) was found in the a-subunit of MCRs from all methanogenic archaea and of the two MCRs from the methanotrophic archaea of the FEBS Journal 274...

Ngày tải lên: 16/03/2014, 05:20

... evolution of the primary structure of the N-terminal regions of TTR and the biological function of TTR 4014 Results Synthesis of recombinant human TTR In the crocodile, TTR is only synthesized in the ... T4) In the other, the N-terminal region of crocTTR was deleted The affinity of T3 and T4 to both TTRs was studied and the results are a powerful demonstration of the relationship between the evolution ... revealed that the region of the subunit which changed in a distinct and directed manner was the N-terminal region The ‘N-terminal region is defined as the amino acids from the N-terminus until the Cys...

Ngày tải lên: 23/03/2014, 10:21

... Asi iN -U 橋 d h ensa oH-O -AYU 篭車 一 F-u Uk ル KU ー K-s Utu b-U uS cuUk h a n E anD? k-S uTU B-u Us CUu H - ・ka N e And? 月 R 靴 ぶす rn a I cny ad big rde cosik hptcs dg o tI rn a g o mrig o d onn ... a δi ， l s ocsoal，o h u o t i rvr w e h dos o of r o h c r w o ie y u hne f o l e h n e rp y u f o t t l k h gvs o cag.Iy u i e e v rt i ae i Koof g aot aig o o r rgt otd o Jpns c s s n yt ，o ... te ci n a s ses ts i Nvrhls，ery vr aaya ad fie ay n s k ad eetees nal eeyslrmn n ofc ld i O a a n truhu asihsland osek tnad aaee o ue n hogotKna a ere t pa sadr Jpns f s i r bsns，lhuh e r rnnito...

Ngày tải lên: 27/03/2014, 12:26

... several of these corepressors also interact with the C-terminal regions of CHD3 downstream of residue 1676 [46] or the conserved regions of CHD4 and dMi2 [50] Models proposed to explain the repression ... indicating the crucial importance of these two Ets motifs [15] In addition to controlling the level of gene expression, Ets factors may direct the choice of the promoter elements in play, and therefore, ... acids, the Ets domain, the CIDD and the C-terminal domain The fragment of cDNA included in the bait used for two-hybrid screening of the brain cDNA library included amino acids 96–510 at the C-terminus...

Ngày tải lên: 30/03/2014, 09:20

... the current study, we sought to investigate the molecular basis of the differential expression of TPa and TPb isoforms Our initial aim was to map the patterns of exon usage in the 5¢ UTR of the ... number of the diverse superfamily of GPCRs, not least among the prostanoid receptor subfamily of GPCRs [53] The EP3 subtype of the PGE2 receptors is one of the most heavily spliced among all of the ... FEBS 2002 Analysis of the TPa and TPb mRNAs (Eur J Biochem 269) 4067 Fig Functional analysis of the 5¢ flanking region of the TP receptor gene (A) Schematic of the TP genomic region spanning nucleotides...

Ngày tải lên: 31/03/2014, 09:20

... as well as the deletions investigated, with the exception of deletion R30hE5, increased the number of colonies and the colony size of keratinocytes growing in soft agar The effect of the empty ... The results shown in this communication demonstrate that the expression of theHPV16 E5 protein increases the number and the size of HaCaT cell colonies growing in soft-agar The results were the ... but determines the number of cells and therefore the colony size (see Fig 6) The data here detailed represent the first quantitative description of the ability of HPV16 E5 to Page of 10 (page number...

Ngày tải lên: 20/06/2014, 01:20

... and will form the basis for evaluating the impact of the project over year period In May-June, Dr Mui and the team from GRRC returned to the farms surveyed and initiated the introduction of the ... Bachthao bucks, to buy these bucks and circulate then around the project farms (and others) over the period of the project The issue here is determining the extent to which they are superior, it ... possible during the time of the project The project will depend on the continuous availability of a reliable vehicle and driver to gain access to the villages, and particularly for some of the remote...

Ngày tải lên: 21/06/2014, 06:20

... Bachthao bucks, to buy these bucks and circulate then around the project farms (and others) over the period of the project The issue here is determining the extent to which they are superior, it ... at the end of the project which will include the final outcome of the technological innovations on the productivity and well-being of Vietnamese goat farmers in these areas Objective Training and ... stage has been the training of DARD officers from Ninh Thuan, Binh Thuan and Lam Dong provinces in goat husbandry and management, in the conduct of surveys and the acquisition of expertise to...

Ngày tải lên: 21/06/2014, 06:20

... diagnosis and treatment of goat diseases in Vietnam, training and information dissemination during the project and the techniques developed and outcomes of pasture research over the years of the project ... activities, including analysis and interpretation of farming system surveys carried out in 2006 and 2008, and of the biology and productivity of goats following the introduction of new technologies to ... Thuan and Lam Dong provinces of southeast Vietnam The title of the report is “New technologies for Improving Goat Production in Vietnam” and includes not only analysis and interpretation of the...

Ngày tải lên: 21/06/2014, 06:20

... stands were not included in the analyses because they not occur in the region of Krušné hory Mts on the given sites In the region of Bohemian-Moravian Upland the analyses included forest stands ... the same height from planting with severe and small root system deformations in the region of Krušné hory Mts and in the region of Bohemian-Moravian Upland (7) Mutual comparison of trees of the ... development and health condition were found either between the trees of identical height from self-seeding and from planting in the region of Krušné hory Mts and in the region of Bohemian-Moravian Upland...

Ngày tải lên: 07/08/2014, 04:20

... subcloned into the plasmid pGEM-3Z to generate the clone pGS217 and used for analysis and sequencing 2.2 Fusions of the 5 region of GS1a to the GUS reporter gene The 981 bp sequence upstream of the translation ... [4,16,18], and none of them correspond to nitrogen metabolism We have studied the promoter activity of the 5’-untranslated region using fusions with the reporter gene uidA and the presence of DNA-protein ... histochemical assays, the 5’upstream region of the pine gene was able to drive gene expression in pine cotyledons To further characterize the function of the 5’upstream region of the pine GS1a gene,...

Ngày tải lên: 08/08/2014, 14:20

... conducted the ELISA experiments and participated in the design of the study and analysis of the data FC participated in the design of the study and in the analysis of data and helped to draft the manuscript ... participated in the design and revision of the study AS participated in the analysis and interpretation of data and helped to draft the manuscript RR participated in the design of the study and in the revision ... the revision of the manuscript EP participated in analysis of data GV participated in the design of the study and in the revision of the manuscript MS conducted the experiments on endothelial cell...

Ngày tải lên: 09/08/2014, 08:22

... Acknowledgements The authors thank all the subjects and doctors for their cooperation in the study Authors’ contributions SA and MI conceived of the study participated in its design and coordination and gave ... (L) in variants of one of the breakthrough (BT1) sample (Table 1) and at position histidine (H) got replaced with Q in variants of one of the rapid responder (R1) (Tables 2) Other amino acid ... WJ, Changchien CS: Mutations in the NS5A and E2-PePHD region of hepatitis C virus type 1b and correlation with the response to combination therapy with interferon and ribavirin J Viral Hepat 2003,...

Ngày tải lên: 11/08/2014, 21:21

... NH and OB conceived of the study, participated in its design, and in drafting the manuscript HT and JB participated in the study design and coordination and in discussing manuscript NH, NBF and ... described by Lindh et al in 1998 [26] The principal advantage of TSP-PCR is the region of the genome targeted by this method; in fact, TSP-PCR amplifies part of the S region which is known to be more ... erroneous results, the limit of the rapid methods using classic PCR is the low sensitivity of DNA detection (the limit of detection of our method being 10 copies/ml) This explains that the genotyping...

Ngày tải lên: 12/08/2014, 02:20

... evaluate the occurrence of calcified intervertebral discs in Finnish miniature dachshunds and to compare the relationship between the curvature of the radius and ulna with the degree of disc calcification ... that the curvature of the legs is proportional to the degree of the chondrodystrophy and by breeding straight-legged dachshunds the occurrence of IDD could be reduced The differences in the curvature ... Most of the sires had only one offspring included in this study (Fig 2) In both breeds there were 65% females and 35% males The ages and weights of the dogs are presented in Table According to the...

Ngày tải lên: 12/08/2014, 15:20

... population in the Archangel and Samara Oblasts and north-western regions of Russia and Estonia [8,27,29] It is therefore likely that the Beijing genotype is a major cause of tuberculosis and particularly ... typing of the isolates from the drug resistance survey was performed to determine the proportion of patients Figure DNA fingerprint and spoligotype patterns of the isolates obtained from five randomly ... from the characteristics of the complete study population of the drug resistance survey (data not shown) In brief, the final sample consisted of 239 male (60%) and 158 female (40%) patients The...

Ngày tải lên: 12/08/2014, 18:20

... results in the formation and/ or exposure of highly conserved regions previously folded into the core structure and/ or sheltered by the variable loops and the glycans covering the outer domain of gp120 ... of infection by the SK3 anti-CD4 mAb (Figure and Tables and 3; only DS17 is shown but the other two clones had the same phenotype) In addition, the mutant Env generated in the background of the ... determinants of phenotypic changes Single mutants were constructed to test for the role of N283 and T283 on the phenotypes observed the identity of the gp120 and gp41 expressed from each construct Furthermore,...

Ngày tải lên: 13/08/2014, 05:21

... great impact on the health profile of the population [2,3] The ANC of the St Mary's Hospital Lacor is located in the Gulu district of North Uganda and has participated in the national HIV-1 sentinel ... (the National Institute of Health of Italy) and AVSI, in collaboration and with the approval of the STD/AIDS Control Programme of The statistical analyses were conducted excluding data for the ... in the North-Central region of Uganda, which also includes the districts of Lira and Apac [4] About 10% of people living in the Acholi region are resident in urban areas and approximately 90%...

Ngày tải lên: 13/08/2014, 13:21

... minorities, and the organisations that work with them, have not received the attention and support of their counterparts in southern parts of the country This has the potential to further limit the ability ... understand the climate vulnerability and capacity of ethnic minorities in the northern mountains of Vietnam it is vital to understand these causes The analysis illustrates the complexity of vulnerability ... populated provinces in the northern midlands and mountain areas of Vietnam Bac Kan province is one of the poorest provinces the northern mountainous Region and in Vietnam overall The poverty rate in...

Ngày tải lên: 08/09/2015, 23:30