Intubation of septic patients with respiratory distress and hemodynamic compromise may result in clinical deterioration and precipitate cardiovascular failure. The decision to intubate is complex and multifactorial. The purpose of this study was to evaluate the impact of intubation in patients with respiratory distress and predominant hemodynamic instability within 24h after ICU admission for septic shock.
(2021) 21:253 Yang et al BMC Anesthesiol https://doi.org/10.1186/s12871-021-01471-x Open Access RESEARCH Outcome after intubation for septic shock with respiratory distress and hemodynamic compromise: an observational study Ting Yang1,2, Yongchun Shen1,2, John G. Park2, Phillip J. Schulte3, Andrew C. Hanson3, Vitaly Herasevich4, Yue Dong4 and Philippe R. Bauer2* Abstract Background: Acute respiratory failure in septic patients contributes to higher in-hospital mortality Intubation may improve outcome but there are no specific criteria for intubation Intubation of septic patients with respiratory distress and hemodynamic compromise may result in clinical deterioration and precipitate cardiovascular failure The decision to intubate is complex and multifactorial The purpose of this study was to evaluate the impact of intubation in patients with respiratory distress and predominant hemodynamic instability within 24 h after ICU admission for septic shock Methods: We conducted a retrospective analysis of a prospective registry of adult patients with septic shock admitted to the medical ICU at Mayo Clinic, between April 30, 2014 and December 31, 2017 Septic shock was defined by persistent lactate > 4 mmol/L, mean arterial pressure