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THÔNG TIN TÀI LIỆU
Cấu trúc
Cover
Contents
Zusammenfassung
Abstract
Chapter I: Introduction
Background
Alcohol dependence
Stages of addiction
Pathophysiology of alcohol dependence
Mesolimbic dopamine system
Imbalance between reward and antireward system
Role of alcohol cues
fMRI and classification techniques
fMRI data
fMRI analysis
Localization of brain activation
Connectivity
Classification/prediction
Aims
Methodology
Chapter II: Formation of functional ROIs
Introduction
Materials and methods
Materials
Methods
Step 1: Constructing the activation patterns
Step 2: Classifying the patterns
Evaluation
Results
Discussion
Chapter III: fMRI classification based on multiple lines of evidence
Classification of pattern
Observation on individual ROIs
Combination of the observation results
Classification of subject
Chapter IV: Imaging approach
Step 1: Constructing the patterns
Step 2: Ranking the patterns
Step 3: Validating the ranking
Chapter V: Feasible applications in clinical practice
Application 1: Feasibility of monitoring treatment response
Results and discussion
Application 2: Correlation between clinical variables and functional imaging
Chapter VI: General discussion and conclusion
Summary of discussion
Conclusions
References
Appendices
Affidavit
Acknowledgments
Nội dung
Ngày đăng: 11/07/2021, 16:21
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