A nomogram model to predict death rate among non-small cell lung cancer (NSCLC) patients with surgery in surveillance, epidemiology, and end results (SEER) database

This study aimed to establish a novel nomogram prognostic model to predict death probability for non-small cell lung cancer (NSCLC) patients who received surgery.

Jia et al BMC Cancer (2020) 20:666 https://doi.org/10.1186/s12885-020-07147-y RESEARCH ARTICLE Open Access A nomogram model to predict death rate among non-small cell lung cancer (NSCLC) patients with surgery in surveillance, epidemiology, and end results (SEER) database Bo Jia1†, Qiwen Zheng2†, Jingjing Wang1†, Hongyan Sun3, Jun Zhao1, Meina Wu1, Tongtong An1, Yuyan Wang1, Minglei Zhuo1, Jianjie Li1, Xue Yang1, Jia Zhong1, Hanxiao Chen1, Yujia Chi1, Xiaoyu Zhai1 and Ziping Wang1* Abstract Background: This study aimed to establish a novel nomogram prognostic model to predict death probability for non-small cell lung cancer (NSCLC) patients who received surgery Methods: We collected data from the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute in the United States A nomogram prognostic model was constructed to predict mortality of NSCL C patients who received surgery Results: A total of 44,880 NSCLC patients who received surgery from 2004 to 2014 were included in this study Gender, ethnicity, tumor anatomic sites, histologic subtype, tumor differentiation, clinical stage, tumor size, tumor extent, lymph node stage, examined lymph node, positive lymph node, type of surgery showed significant associations with lung cancer related death rate (P < 0.001) Patients who received chemotherapy and radiotherapy had significant higher lung cancer related death rate but were associated with significant lower non-cancer related mortality (P