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535CHAPTER 47 Diseases of the Upper Respiratory Tract and after resolution of airway and facial edema While intubated, a wire cutter should be kept at the patient’s bedside at all times in case emerge[.]

CHAPTER 47  Diseases of the Upper Respiratory Tract A 535 and after resolution of airway and facial edema While intubated, a wire cutter should be kept at the patient’s bedside at all times in case emergency access to the oral cavity is needed In the event of emesis, the patient should be leaned forward or the wires should be emergently cut to prevent aspiration Injury to the airway may also result from blunt or penetrating laryngeal trauma Fortunately, these events are rare in pediatric patients, occurring in only 0.0001% of emergency department trauma patients.104 An increasing trend in laryngeal trauma among young children has been observed due to motor vehicle accidents.105 Other mechanisms include athletic injuries, child abuse, and suicide attempts by hanging Airway trauma occurs most commonly in males, and the average age of affected patients is 10 years old Direct trauma to the larynx can cause a number of injuries, including mucosal edema, hematomas, hyoid and laryngeal fractures, or even laryngotracheal separation.101 Common presenting symptoms include dysphagia, odynophagia, voice changes, hemoptysis, ecchymosis, and subcutaneous emphysema.106 Subcutaneous emphysema following laryngeal trauma often indicates a mucosal tear with communication between the airway lumen with the soft tissue of the neck The degree of subcutaneous emphysema does not correlate with the severity of the injury.107 The safest practice for these patients is an airway evaluation in the operating room Depending on the type of injury, treatment may include observation, endotracheal intubation to allow healing, or surgical reconstruction with tracheostomy placement.105 Voice and swallowing dysfunction may be long-term morbidities Key References B • Fig 47.18  ​Inspiratory chest radiograph with foreign body present in left mainstem bronchus During inspiration (A), the left lung is slightly hyperinflated but could be considered normal The expiratory radiograph​ (B) clearly demonstrates that the left lung is hyperinflated because of air trapping by the foreign body (Courtesy Eric Effmann, MD.) of airway compromise from hemorrhage and delayed soft tissue swelling Those treating a trauma patient should consider multiple ways to secure the airway and have supplies available for endotracheal intubation, flexible fiberoptic nasotracheal intubation, and emergent cricothyroidotomy Even after surgical repair of their injuries, patients with facial trauma may have complex airway concerns, such as external fixation devices or jaw wiring These patients should undergo extubation only when fully awake Brigger MT, Hartnick CJ Surgery for pediatric vocal cord paralysis: a meta-analysis Otolaryngol Head Neck Surg 2002;126(4):349-355 Brown OE, Pownell P, Manning SC Choanal atresia: a new anatomic classification and clinical management applications Laryngoscope 1996;106(1):97-101 Derkay CS, Wiatrak B Recurrent respiratory papillomatosis: a review Laryngoscope 2008;118(7):1236-1247 Duval M, Tarasidis G, Grimmer JF, et al Role of operative airway evaluation in children with recurrent croup: a retrospective cohort study Clin Otolaryngol 2015;40(3):227-233 Léauté-Labrèze C, de la Roque ED, Hubiche T, Boralevi F, Thambo JB, Taïeb A Propranolol for severe hemangiomas of infancy N Engl J Med 2008;358(24):2649-2651 Pezzettigotta SM, Leboulanger N, Roger G, Denoyelle F, Garabédian EN Laryngeal cleft Otolaryngol Clin North Am 2008; 41(5):913-933, ix Thompson DM Abnormal sensorimotor integrative function of the larynx in congenital laryngomalacia: a new theory of etiology Laryngoscope 2007;117(suppl 114):1-33 The full reference list for this chapter is available at ExpertConsult.com e1 References Hammer J Acute respiratory failure in children Paediatr Respir Rev 2013;14(2):64-69 Tobias JD Pediatric Airway anatomy may not be what we thought: implications for clinical practice and the use of cuffed endotracheal tubes Paediatr Anaesth 2015;2:9-19 Litman RS, Weissend EE, Shibata D, et al Developmental changes of laryngeal dimensions in unparalyzed, sedated children Anesth Analg 2003;98:41-45 Dalal PG, Murray D, Messner AH, et al Pediatric laryngeal dimensions: an age-based analysis Anesth Analg 2009;108:1475-1479 Wetmore RF, Muntz HR, McGill TJI Pediatric Otolaryngology: Principles and Practice Pathways 2nd ed New York: Thieme; 2012 Ramsden JD, Campisi P, Forte V Choanal atresia and choanal stenosis Otolaryngol Clin North Am 2009;42(2):339-352 Brown OE, Pownell P, Manning SC Choanal atresia: a new anatomic classification and clinical management applications Laryngoscope 1996;106(1):97-101 Samadi DS, Shah UK, Handler SD Choanal atresia: a twenty-year review of medical comorbidities and surgical outcomes Laryngoscope 2003;113(2):254-258 Kwong KM Current updates on choanal atresia Front Pediatr 2015;3:52 10 Corrales CE, Koltai PJ Choanal atresia: current concepts and controversies Curr Opin Otolaryngol Head Neck Surg 2009;17(6): 466-470 11 Burrow TA, Saal HM, de Alarcon A, Martin LJ, Cotton RT, Hopkin RJ Characterization of congenital anomalies in individuals with choanal atresia Arch Otolaryngol Head Neck Surg 2009; 135(6):543 12 Keller JL, Kacker A Choanal atresia, charge association, and congenital nasal stenosis Otolaryngol Clin North Am 2000;33(6):13431351 13 Miller MJ, Martin RJ, Carlo WA, Fouke JM, Strohl KP, Fanaroff AA Oral breathing in newborn infants J Pediatr 1985;107(3):465-469 14 Friedman N, Mitchell R, Bailey C, Albert D, Leighton SE Management and outcome of choanal atresia correction Int J Pediatr Otorhinolaryngol 2000;52(1):45-51 15 Landry AM, Thompson DM Laryngomalacia: disease presentation, spectrum, and management Int J Pediatr 2012;2012:1-6 16 Dobbie AM, White DR Laryngomalacia Pediatr Clin North Am 2013;60(4):893-902 17 Richter GT, Wootten CT, Rutter MJ, Thompson DM Impact of supraglottoplasty on aspiration in severe laryngomalacia Ann Otol Rhinol Laryngol 2009;118(4):259-266 18 Dickson JM, Richter GT, Meinzen-Derr J, Rutter MJ, Thompson DM Secondary airway lesions in infants with laryngomalacia Ann Otol Rhinol Laryngol 2009;118(1):37-43 19 Thompson DM Laryngomalacia: factors that influence disease severity and outcomes of management Curr Opin Otolaryngol Head Neck Surg 2010;18(6):564-570 20 Qubty WF, Mrelashvili A, Kotagal S, Lloyd RM Comorbidities in infants with obstructive sleep apnea J Clin Sleep Med 2014;10(11):1213-1216 21 Richter GT, Thompson DM The surgical management of laryngomalacia Otolaryngol Clin North Am 2008;41(5):837-864 22 Thompson DM Abnormal sensorimotor integrative function of the larynx in congenital laryngomalacia: a new theory of etiology Laryngoscope 2007;117(suppl 114):1-33 23 Farhood Z, Ong AA, Nguyen SA, Gillespie MB, Discolo CM, White DR Objective outcomes of supraglottoplasty for children with laryngomalacia and obstructive sleep apnea: a meta-analysis JAMA Otolaryngol Head Neck Surg 2016;142(7):665 24 Nicollas R, Triglia JM The anterior laryngeal webs Otolaryngol Clin North Am 2008;41(5):877-888 25 Cohen SR Congenital glottic webs in children: a retrospective review of 51 patients Ann Otol Rhinol Laryngol 1985;94(suppl 6):2-16 26 Wyatt ME, John Hartley BE Laryngotracheal reconstruction in congenital laryngeal webs and atresias Otolaryngol Head Neck Surg 2005;132(2):232-238 27 D’Eufemia MD, Cianci S, Di Meglio F, et al Congenital high airway obstruction syndrome (CHAOS): discussing the role and limits of prenatal diagnosis starting from a single-center case series J Prenat Med 2016;10(1-2):4-7 28 Ramesar K, Albizzati C Laryngeal cysts: clinical relevance of a modified working classification J Laryngol Otol 1988;102(10):923925 29 Holinger LD, Barnes DR, Smid LJ, Holinger PH Laryngocele and saccular cysts Ann Otol Rhinol Laryngol 1978;87(5):675-685 30 Macfie DD Asymptomatic laryngoceles in wind-instrument bandsmen Arch Otolaryngol Head Neck Surg 1966;83(3):270-275 31 Zawadzka-Glos L, Frackiewicz M, Brzewski M, Biejat A, Chmielik M Difficulties in diagnosis of laryngeal cysts in children Int J Pediatr Otorhinolaryngol 2009;73(12):1729-1731 32 Pezzettigotta SM, Leboulanger N, Roger G, Denoyelle F, Garabédian EN Laryngeal cleft Otolaryngol Clin North Am 2008; 41(5):913-933, ix 33 Evans KL, Courteney-Harris R, Bailey CM, Evans JNG, Parsons DS Management of posterior laryngeal and laryngotracheoesophageal clefts Arch Otolaryngol Head Neck Surg 1995;121(12):1380-1385 34 Benjamin B, Inglis A Minor congenital laryngeal clefts: diagnosis and classification Ann Otol Rhinol Laryngol 1989;98(6):417-420 35 Brigger MT, Hartnick CJ Surgery for pediatric vocal cord paralysis: a meta-analysis Otolaryngol Head Neck Surg 2002;126(4):349-355 36 King EF, Blumin JH Vocal cord paralysis in children Curr Opin Otolaryngol Head Neck Surg 2009;17(6):483-487 37 Vats A, Worley GA, de Bruyn R, Porter H, Albert DM, Bailey CM Laryngeal ultrasound to assess vocal fold paralysis in children J Laryngol Otol 2004;118(6):429-431 38 Rosin DF, Handler SD, Potsic WP, Wetmore RF, Tom LWC Vocal cord paralysis in children Laryngoscope 1990;100(11):1174-1179 39 Daya H, Hosni A, Bejar-Solar I, Evans JNG, Bailey CM Pediatric vocal fold paralysis: a long-term retrospective study Arch Otolaryngol Head Neck Surg 2000;126(1):21 40 Chen EY, Inglis AF Bilateral vocal cord paralysis in children Otolaryngol Clin North Am 2008;41(5):889-901 41 Rizzardi E, Tagliaferro T, Snijders D, et al Unilateral laryngeal paralysis in a newborn with congenital varicella syndrome Int J Pediatr Otorhinolaryngol 2009;73(1):115-118 42 Lesnik M, Thierry B, Blanchard M, et al Idiopathic bilateral vocal cord paralysis in infants: Case series and literature review: Idiopathic Bilateral Laryngeal Palsy Laryngoscope 2015;125(7):1724-1728 43 Jabbour J, Martin T, Beste D, Robey T Pediatric vocal fold immobility: natural history and the need for long-term follow-up JAMA Otolaryngol Head Neck Surg 2014;140(5):428 44 Kussman BD, Geva T, McGowan FX Cardiovascular causes of airway compression Paediatr Anaesth 2004;14(1):60-74 45 Aalderen WMC, Hoekstra MO, Hess J, Gerritsen J, Knol K Respiratory infections and vascular rings Acta Paediatr 1990;79(4):477-480 46 Shah RK, Mora BN, Bacha E, et al The presentation and management of vascular rings: an otolaryngology perspective Int J Pediatr Otorhinolaryngol 2007;71(1):57-62 47 Wine TM, Colman KL, Mehta DK, Maguire RC, Morell VO, Simons JP Aortopexy for innominate artery tracheal compression in children Otolaryngol Head Neck Surg 2013;149(1):151-155 48 Derkay CS, Wiatrak B Recurrent respiratory papillomatosis: a review Laryngoscope 2008;118(7):1236-1247 49 Venkatesan NN, Pine HS, Underbrink MP Recurrent respiratory papillomatosis Otolaryngol Clin North Am 2012;45(3):671-694, viii-ix 50 Rimell FL, Shoemaker DL, Pou AM, Jordan JA, Post JC, Ehrlich GD Pediatric respiratory papillomatosis: prognostic role of viral typing and cofactors Laryngoscope 1997;107(7):915-918 51 Derkay CS Task force on recurrent respiratory papillomas: a preliminary report Arch Otolaryngol Head Neck Surg 1995;121(12):1386-1391 e2 52 Sie KCY, McGill T, Healy GB Subglottic hemangioma: ten years’ experience with the carbon dioxide laser Ann Otol Rhinol Laryngol 1994;103(3):167-172 53 Holinger PH, Brown WT LVI congenital webs, cysts, laryngoceles and other anomalies of the larynx Ann Otol Rhinol Laryngol 1967; 76(4):744-752 54 O-Lee TJ, Messner A Subglottic hemangioma Otolaryngol Clin North Am 2008;41(5):903-911, viii-ix 55 Orlow SJ, Isakoff MS, Blei F Increased risk of symptomatic hemangiomas of the airway in association with cutaneous hemangiomas in a “beard” distribution J Pediatr 1997;131(4):643-646 56 Bruckner AL, Frieden IJ Infantile hemangiomas J Am Acad Dermatol 2006;55(4):671-682 57 Léauté-Labrèze C, de la Roque ED, Hubiche T, Boralevi F, Thambo JB, Taïeb A Propranolol for severe hemangiomas of infancy N Engl J Med 2008;358(24):2649-2651 58 Barnes C, Sexton M, Sizeland A, Tiedemann K, Berkowitz RG, Waters K Laryngo-pharyngeal carcinoma in childhood Int J Pediatr Otorhinolaryngol 2001;61(1):83-86 59 Johnson DW Croup BMJ Clin Evid 2014;2014:0321 60 Wall SR, Wat D, Spiller OB, Gelder CM, Kotecha S, Doull IJM The viral aetiology of croup and recurrent croup Arch Dis Child 2009;94(5):359-360 61 Geelhoed GC, Macdonald WBG Oral and inhaled steroids in croup: a randomized, placebo-controlled trial Pediatr Pulmonol 1995;20(6):355-361 62 Westley CR Nebulized racemic epinephrine by ippb for the treatment of croup: a double-blind study Am J Dis Child 1978; 132(5):484 63 Brown JC The management of croup Br Med Bull 2002;61: 189-202 64 Bjornson C, Russell K, Vandermeer B, Klassen TP, Johnson DW Nebulized epinephrine for croup in children Cochrane Database Syst Rev 2013;(10):CD006619 65 Russell KF, Liang Y, O’Gorman K, Johnson DW, Klassen TP Glucocorticoids for croup Cochrane Database Syst Rev 2011;(1): CD001955 66 Johnson DW, Jacobson S, Edney PC, Hadfield P, Mundy ME, Schuh S A comparison of nebulized budesonide, intramuscular dexamethasone, and placebo for moderately severe croup N Engl J Med 1998;339(8):498-503 67 Klassen TP, Craig WR, Moher D, et al Nebulized budesonide and oral dexamethasone for treatment of croup: a randomized controlled trial JAMA 1998;279(20):1629 68 Adderley RJ, Mullins GC When to extubate the croup patient: the “leak” test Can J Anaesth 1987;34(3):304-306 69 Duval M, Tarasidis G, Grimmer JF, et al Role of operative airway evaluation in children with recurrent croup: a retrospective cohort study Clin Otolaryngol 2015;40(3):227-233 70 Shah RK, Roberson DW, Jones DT Epiglottitis in the Haemophilus influenzae type B vaccine era: changing trends Laryngoscope 2004;114(3):557-560 71 Sobol SE, Zapata S Epiglottitis and croup Otolaryngol Clin North Am 2008;41(3):551-566 72 Blackstock D, Adderley RJ, Steward DJ Epiglottitis in young infants Anesthesiology 1987;67(1):97-100 73 Stroud RH, Friedman NR An update on inflammatory disorders of the pediatric airway: Epiglottitis, croup, and tracheitis Am J Otolaryngol 2001;22(4):268-275 74 Salamone FN, Bobbitt DB, Myer CM, Rutter MJ, Greinwald JH Bacterial tracheitis reexamined: Is there a less severe manifestation? Otolaryngol Head Neck Surg 2004;131(6):871-876 75 Eckel HE, Widemann B, Damm M, Roth B Airway endoscopy in the diagnosis and treatment of bacterial tracheitis in children Int J Pediatr Otorhinolaryngol 1993;27(2):147-157 76 Gallagher PG, Myer CM An approach to the diagnosis and treatment of membranous laryngotracheobronchitis in infants and children Pediatr Emerg Care 1991;7(6):337-342 77 Fordham MT, Rock AN, Bandarkar A, et al Transcervical ultrasonography in the diagnosis of pediatric peritonsillar abscess: transcervical US in pediatric PTA Laryngoscope 2015;125(12):2799-2804 78 Ryan JT, Preciado DA, Bauman N, et al Management of pediatric orbital cellulitis in patients with radiographic findings of subperiosteal abscess Otolaryngol Head Neck Surg 2009;140(6):907-911 79 Brook I Fusobacterial head and neck infections in children Int J Pediatr Otorhinolaryngol 2015;79(7):953-958 80 Vieira F, Allen SM, Stocks RMS, Thompson JW Deep neck infection Otolaryngol Clin North Am 2008;41(3):459-483, vii 81 Georget E, Gauthier A, Brugel L, et al Acute cervical lymphadenitis and infections of the retropharyngeal and parapharyngeal spaces in children BMC Ear Nose Throat Disord 2014;14(1):8 82 Malloy KM, Christenson T, Meyer JS, et al Lack of association of CT findings and surgical drainage in pediatric neck abscesses Int J Pediatr Otorhinolaryngol 2008;72(2):235-239 83 Jefferson ND, Cohen AP, Rutter MJ Subglottic stenosis Semin Pediatr Surg 2016;25(3):138-143 84 Tobias JD, Schwartz L, Rice J, Jatana K, Kang DR Cuffed endotracheal tubes in infants and children: Should we routinely measure the cuff pressure? Int J Pediatr Otorhinolaryngol 2012;76(1):61-63 85 Newth CJL, Rachman B, Patel N, Hammer J The use of cuffed versus uncuffed endotracheal tubes in pediatric intensive care J Pediatr 2004;144(3):333-337 86 Litman RS, Maxwell LG Cuffed versus uncuffed endotracheal tubes in pediatric anesthesia: the debate should finally end Anesthesiology 2013;118(3):500-501 87 Myer CM, O’Connor DM, Cotton RT Proposed grading system for subglottic stenosis based on endotracheal tube sizes Ann Otol Rhinol Laryngol 1994;103(4):319-323 88 Sittel C Pathologies of the larynx and trachea in childhood GMS Curr Top Otorhinolaryngol Head Neck Surg 2014;13:Doc09 89 Jacobs BR, Salman BA, Cotton RT, Lyons K, Brilli RJ Postoperative management of children after single-stage laryngotracheal reconstruction Crit Care Med 2001;29(1):164-168 90 Yellon RF, Parameswaran M, Brandom BW Decreasing morbidity following laryngotracheal reconstruction in children Int J Pediatr Otorhinolaryngol 1997;41(2):145-154 91 Gergin O, Adil EA, Kawai K, Watters K, Moritz E, Rahbar R Indications of pediatric tracheostomy over the last 30 years: Has anything changed? Int J Pediatr Otorhinolaryngol 2016;87:144-147 92 Adly A, Youssef TA, El-Begermy MM, Younis HM Timing of tracheostomy in patients with prolonged endotracheal intubation: a systematic review Eur Arch Otorhinolaryngol 2018;275(3):679-690 93 Griffiths J, Barber VS, Morgan L, Young JD Systematic review and meta-analysis of studies of the timing of tracheostomy in adult patients undergoing artificial ventilation BMJ 2005;330(7502):1243 94 Holloway AJ, Spaeder MC, Basu S Association of timing of tracheostomy on clinical outcomes in PICU patients Pediatr Crit Care Med 2015;16(3):e52-e58 95 Campisi P, Forte V Pediatric tracheostomy Semin Pediatr Surg 2016;25(3):191-195 96 Bluestone CD, Simons JP, Healy GB Bluestone and Stool’s: Pediatric Otolaryngology 5th ed Shelton, CT: People’s Medical Publishing House; 2014 97 Sidell DR, Kim IA, Coker TR, Moreno C, Shapiro NL Food choking hazards in children Int J Pediatr Otorhinolaryngol 2013;77(12):1940-1946 98 Altkorn R, Chen X, Milkovich S, et al Fatal and non-fatal food injuries among children (aged 0–14 years) Int J Pediatr Otorhinolaryngol 2008;72(7):1041-1046 99 Hughes CA, Baroody FM, Marsh BR Pediatric tracheobronchial foreign bodies: historical review from the Johns Hopkins Hospital Ann Otol Rhinol Laryngol 1996;105(7):555-561 100 Wolach B, Raz A, Weinberg J, Mikulski Y, Ari JB, Sadan N Aspirated foreign bodies in the respiratory tract of children: eleven years experience with 127 patients Int J Pediatr Otorhinolaryngol 1994;30(1):1-10 e3 101 Reid A, Ha JF Inhalational injury and the larynx: a review Burns 2019;45(6):1266-1274 102 Freno D, Sahawneh J, Harrison S, Sahawneh T, Patterson S, Kahn SA Determining the role of nasolaryngoscopy in the initial evaluation for upper airway injury in patients with facial burns Burns 2018;44(3):539-543 103 Kadilak PR, Vanasse S, Sheridan RL Favorable short- and longterm outcomes of prolonged translaryngeal intubation in critically ill children J Burn Care Rehabil 2004;25(3):262-265 104 Gold SM, Gerber ME, Shott SR, Myer CM Blunt laryngotracheal trauma in children Arch Otolaryngol Head Neck Surg 1997;123(1): 83-87 105 Wootten CT, Bromwich MA, Myer CM Trends in blunt laryngotracheal trauma in children Int J Pediatr Otorhinolaryngol 2009;73(8):1071-1075 106 Humar A, Pitters C Emergency department management of blunt cervical tracheal trauma in children Pediatr Emerg Care 1991;7(5):291-293 107 Shires CB, Preston T, Thompson J Pediatric laryngeal trauma: a case series at a tertiary children’s hospital Int J Pediatr Otorhinolaryngol 2011;75(3):401-408 e4 Abstract: Diseases of the upper airway are common in the pediatric population and pose a significant risk of morbidity and mortality Congenital malformations, neoplasms, infections, and iatrogenic disease such as stenosis are the most frequent underlying etiologies Understanding the anatomy and physiology of the region is key to understanding the pathology Airway disease most often manifests with symptoms such as increased work of breathing, tachypnea, stridor, and cyanotic events Treatment consists of supportive respiratory care, which can range from supplemental oxygen to endotracheal intubation It is crucial to utilize a multidisciplinary team when managing airway disease, including members from critical care, anesthesiology, and otolaryngology Key words: upper airway, airway obstruction, airway masses, airway compression, deep neck space infections ... Otorhinolaryngol 2009;73(1):115-118 42 Lesnik M, Thierry B, Blanchard M, et al Idiopathic bilateral vocal cord paralysis in infants: Case series and literature review: Idiopathic Bilateral Laryngeal Palsy Laryngoscope... 2000;33(6):13431351 13 Miller MJ, Martin RJ, Carlo WA, Fouke JM, Strohl KP, Fanaroff AA Oral breathing in newborn infants J Pediatr 1985;107(3):465-469 14 Friedman N, Mitchell R, Bailey C, Albert... Muntz HR, McGill TJI Pediatric Otolaryngology: Principles and Practice Pathways 2nd ed New York: Thieme; 2012 Ramsden JD, Campisi P, Forte V Choanal atresia and choanal stenosis Otolaryngol Clin

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