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Diagn Ther 2017 [Epub before print] Fetal aortic distensibility may be measured using speckle tracking of the thoracic aortic circumference—the fractional area change The relationship between fetal blood pressure and this measure is validated in an animal model in this paper Yeo L, Romero R Color and power doppler combined with fetal intelligent navigation echocardiography (FINE) to evaluate the fetal heart Ultrasound Obstet Gynecol 2017;50(4):476–491 Fetal Intelligent Navigation Echocardiography (FINE) is a novel computer-aided method developed by the authors to assist in interpretation of the fetal heart from three dimensional volumes of by creating a series of standard echocardiography views Yeo L, Romero R Prenatal diagnosis of hypoplastic left heart and coarctation of the aorta with color doppler FINE Ultrasound Obstet Gynecol 2017;50(4):543–544 This paper builds on previous work by the authors and describes how congenital heart defects may be recognised using fetal intelligent navigation echocardiography combined with color Doppler References Keller BB, Hu N, Tinney JP Embryonic ventricular diastolic and systolic pressurevolume relation Cardiol Young 1994;4:19–27 Kirby ML Development of the fetal heart Polin RA, Fox WW Fetal and Neonatal Physiology Saunders: Philadelphia, PA; 1992:589–597 Jackson M, Connell MG, Smith A Development of the collagen network of the human fetal myocardium: an immunohistochemical study Int J Cardiol 1993;41:77–86 Mitchell JL, Cuneo BF, Etheridge SP, et al Fetal heart rate predictors of long QT syndrome Circulation 2012;126(23):2688–2695 Hu N, Connuck DM, Keller BB, Clark EB Diastolic filling characteristics in the stage 12 to 27 chick embryo ventricle Pediatr Res 1991;29:334–337 Benson DW Jr, Hughes SF, Hu N, Clark EB Effect of heart rate increase on dorsal aortic flow before and after volume loading in the stage 24 chick embryo Pediatr Res 1999;26:245–249 Vaccaro H, Amor F, Leyton M, Sepulveda W Arrhythmia in early pregnancy: a predictor of first-trimester pregnancy loss Ultrasound Obstet Gynecol 1998;12:248–251 Fine C, St John Sutton MG, Cartier MS, Doubilet PM Variation in heart rate in the normal human fetus during and after cardiogenesis Circulation 1988;78(supplII):397 Kirby ML, McKenzie JW, Weidman TA Developing innervation of the chick heart: a histofluorescence and light microscopic study of sympathetic innervation Anat Rec 1980;196:333–340 10 Markowitz C Response of explanted embryonic cardiac tissues to epinephrine and acetylcholine Am J Physiol 1931;97:271–275 11 Friedman WF, Pool PE, Jacobowitz D, Seagren SC, Braunwald E Sympathetic innervation of the developing rabbit heart Biochemical and histochemical comparisons of fetal, neonatal, and adult myocardium Circ Res 1968;23:25– 32 12 Okuda H, Nakanishi T, Nakazawa M, Takao A Effect of isoproterenol on myocardial mechanical function and cyclic AMP content in the fetal rabbit J Mol Cell Cardiol 1987;19:151–157 13 Delgado C, Artiles A, Gomez AM, Vassort G Frequency-dependent increase in cardiac ca(2+)