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  • SECTION III: Signs and Symptoms

    • CHAPTER 75: STRIDOR

      • INTRODUCTION

      • PATHOPHYSIOLOGY

      • DIFFERENTIAL DIAGNOSIS

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Gerber MA, Baltimore RS, Eaton CB, et al Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics Circulation 2009;119(11):1541–1551 Goldenberg NA, Knapp-Clevenger R, Hays T, et al Lemierre’s and Lemierre’s like syndromes in children: survival and thromboembolic outcomes Pediatrics 2005;116(4):e543–e548 Heath CW Jr, Brodsky AL, Potolsky AI Infectious mononucleosis in a general population Am J Epidemiol 1972;95(1):46–52 Henke CD, Kurland LT, Elveback LR Infectious mononucleosis in Rochester, Minnesota, 1950 through 1969 Am J Epidemiol 1973;98(6):483–490 Komaroff AL, Aronson MD, Pass TM, et al Serologic evidence of chlamydial and mycoplasmal pharyngitis in adults Science 1983;222(4626):927–929 Lindgren C, Neuman MI, Monuteaux MC, et al Patient and parent-reported signs and symptoms for group A streptococcal pharyngitis Pediatrics 2016;138(1):e20160317 MacKenzie A, Fuite LA, Chan FT, et al Incidence and pathogenicity of Arcanobacterium haemolyticum during a 2-year study in Ottawa Clin Infect Dis 1995;21:177–181 McIsaac WJ, Kellner JD, Aufricht P, et al Empirical validation of guidelines for the management of pharyngitis in children and adults JAMA 2004;291(13):1587–1595 Shapiro D, Lindgren CE, Neuman MI, et al Viral features and testing for streptococcal pharyngitis Pediatrics 2017;139(5):e20163403 Shulman ST, Bisno AL, Clegg HW, et al Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America Clin Infect Dis 2012;55(10):1279–1282 Weisner PJ, Tronca E, Bonin P, et al Clinical spectrum of pharyngeal gonococcal infection N Engl J Med 1973;288(4):181–185 Wessels MR Clinical practice Streptococcal pharyngitis N Engl J Med 2011;364(7):648–655 Additional Resources Online eFIGURE 74.1 Lesions of herpetic stomatitis (From Fleisher GR, Ludwig W, Baskin MN Atlas of Pediatric Emergency Medicine Philadelphia, PA: Lippincott Williams & Wilkins; 2004.) eFIGURE 74.2 This left-sided peritonsillar abscess demonstrates swelling and fluctuance of the left tonsil with deviation of the uvula to the opposite side (Courtesy of Zwillenberg S In: Jensen S, ed Nursing Health Assessment 2nd ed Philadelphia, PA: Wolters Kluwer Health; 2014 With permission.) eFIGURE 74.3 A: Conjunctival injection and facial rash and (B ) oral mucosa involvement in Stevens–Johnson syndrome (Reprinted with permission from Fleisher GR, Ludwig W, Baskin MN Atlas of Pediatric Emergency Medicine Philadelphia, PA: Lippincott Williams & Wilkins; 2004.) CHAPTER 75 ■ STRIDOR ERIC C HOPPA, HOLLY E PERRY INTRODUCTION Stridor, although a relatively common occurrence, can be frightening to both children and parents The presence of stridor necessitates a complete and careful evaluation to determine the cause of this worrisome and occasionally lifethreatening symptom This chapter presents the causes of stridor and provides the emergency clinician with guidelines for initial evaluation and management PATHOPHYSIOLOGY Stridor is a respiratory sound caused by turbulent airflow through a partially obstructed upper airway Stridor can be inspiratory, expiratory, or biphasic depending on the anatomic level of airway obstruction Inspiratory stridor occurs with obstruction of the extrathoracic trachea, biphasic stridor when the obstruction is at the level of the glottis or subglottis, usually with a fixed obstruction, and expiratory stridor when only the intrathoracic trachea is involved The pitch of the stridor also varies with the location of the obstruction Laryngeal and subglottic obstructions are associated with high-pitched stridor In contrast, obstruction of the nares and nasopharynx results in a lower-pitched snoring or snorting sound called stertor Because the passage of saliva and the flow of air are impeded in pharyngeal obstruction, these patients often have a gurgling quality of breathing The relative length of inspiratory and expiratory phases may be helpful in localizing the airway obstruction Laryngeal obstruction results in an increased inspiratory phase, whereas expiration tends to be prolonged in bronchial obstruction Both inspiratory and expiratory phases are increased in patients with tracheal obstruction DIFFERENTIAL DIAGNOSIS Stridor may occur in a wide variety of disease processes affecting the large airways from the level of the nares to the bronchi, but most often arises with disorders of the larynx and trachea ( Table 75.1 ) For the purposes of differential diagnosis, it is helpful to categorize the common causes of stridor as acute or chronic in onset and to further divide acute onset into febrile and afebrile causes ( Table 75.2 ) Life-threatening causes of stridor must be considered early during the evaluation process ( Table 75.3 ) ...eFIGURE 74.1 Lesions of herpetic stomatitis (From Fleisher GR, Ludwig W, Baskin MN Atlas of Pediatric Emergency Medicine Philadelphia, PA: Lippincott Williams & Wilkins; 2004.) eFIGURE 74.2 This left-sided... Stevens–Johnson syndrome (Reprinted with permission from Fleisher GR, Ludwig W, Baskin MN Atlas of Pediatric Emergency Medicine Philadelphia, PA: Lippincott Williams & Wilkins; 2004.) CHAPTER 75 ■ STRIDOR... occasionally lifethreatening symptom This chapter presents the causes of stridor and provides the emergency clinician with guidelines for initial evaluation and management PATHOPHYSIOLOGY Stridor

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