Tài liệu Pharmaceutical Coating Technology (Part 8) pptx
Tài liệu Pharmaceutical Coating Technology (Part 8) pptx
... efficiency is reduced
during the coating process. This will affect the coating, resulting in a reduction of the rate of
evaporation, a reduction in the spray rate and longer coating times. It is, therefore, ... pneumatically from a silo to the coating pan. The illustrations in
Fig. 8.11
shows a silo feeding tablets into the coating pan.
Page 217
Fig. 8.10 Laboratory coating Pa...
Tài liệu Pharmaceutical Coating Technology (Part 2) pptx
... R.C. & White, E.F.T. (19 88)
Int. J. Pharm.
48,
63–77.
Handbook of Pharmaceutical Excipients (1986) American Pharmaceutical Association, Washington and
Royal Pharmaceutical Society, London. ... Easterbrook, M.G. & Hogan, J.E. (1992)
Proc. 11th Int. Pharmaceutical Technology
Conf., Manchester.
Kent, D.J. & Rowe, R.C. (19 78) J. Pharm. Pharmacol.
30,
808–810.
Kov...
Tài liệu Pharmaceutical Coating Technology (Part 15) pptx
... from organic solvent coating to aqueous coating?
Answer:
Looking first of all at the formulation-based parameters, there is a need to increase the
solids loading of the coating suspension to ... used for making coating suspensions of aqueous
systems.
4. Question:
When do I need to add a plasticizer to a coating formula?
Answer:
Generally plasticizers are added to coating fo...
Tài liệu Pharmaceutical Coating Technology (Part 1) ppt
...
• Sugar coating
• Film coating
• Particulate/pellet coating
• Compression coating.
Page i
Pharmaceutical Coating Technology
Page 3
one hundred of these pans to be installed in a coating department. ...
The coating process
Graham C.Cole
Summary 170
7.1 Process development of aqueous film coating 170
7.2 Theoretical considerations of film coating 172
7.3 The mec...
Tài liệu Pharmaceutical Coating Technology (Part 3) pdf
... steps
involved in sugar coating are covered in som
e
detail, i.e. sealing, subcoating, smoothing, colour coating,
polishing and
printing.
In the section dealing with subcoating several suitable ... the dosage form.
3.1 INTRODUCTION
The pharmaceutical process of sugar coating remains a widely practised technology despite the interest
arising from film -coating techniques since...
Tài liệu Pharmaceutical Coating Technology (Part 4) pdf
...
practice in pharmaceutical coating, the ability of the coating equipment to evaporate the solvent
satisfactorily may be overcome and the product overwetted, resulting in poor-quality coatings. ... granule or multiparticulate film coating to date, since those
available either have difficulty in coping with the flow rates required for either organic or aqueous film
coating, produce d...
Tài liệu Pharmaceutical Coating Technology (Part 5) ppt
... process of film coating of pharmaceutical solid dosage forms, one cannot
escape a consideration of surface aspects relating to the wetting of granule, pellet or tablet cores by the
coating solution ... to produce much more efficient and
elegant films.
Film coatings are invariably applied in the pharmaceutical industry by spraying a coating solution or
suspension onto the surface...
Tài liệu Pharmaceutical Coating Technology (Part 6) pdf
... designed for aqueous film coating in a side-vented pan. A
comparison is made of energy requirements of a column -coating system and a coating pan.
All the major operational coating parameters can ...
Q=GC
p
.ΔT=9010×0.25×4.2×40
Table 6.3
Energy balance: comparison of a 1500 mm diameter coating pan and a 450 mm fluidized bed coating
column
1500 mm coating pan 450 mm column...
Tài liệu Pharmaceutical Coating Technology (Part 7) doc
... 170
7
The coating process
Graham C.Cole
SUMMARY
In recent years tablet coating has undergone several fundamental changes. The original sugar -coating
technique has been largely replaced by film -coating ... parts of the equipment can provide a reduction in the
overall coating cycle.
7.1 PROCESS DEVELOPMENT OF AQUEOUS FILM COATING
Coating of tablets and pills is one of the oldest...
Tài liệu Pharmaceutical Coating Technology (Part 9) pdf
... is expensive and is
generally the reason for pharmaceutical companies to convert coating formulations to aqueous systems
or formulate aqueous coating for all new products.
Where this is not ...
moisture from the core during the coating process. Weighing the tablets before and after coating will
not, therefore, give an absolute measure of the weight of coating deposited. Vario...