... J M, Thomas S H L2001 Anti-TNF agents for rheumatoid arthritis.British Journal of Clinical Pharmacology 51: 201-208Sneader W 2000 The discovery of aspirin: areappraisal. British ... all being important.SYMPTOMATICTREATMENTNSAIDs provide much symptomatic relief andimprove clinical indicators of disease activity such asjoint swelling, but do not improve its outcome, ... pathogenesis ofrheumatoid arthritis. The onset of action is fasterthan other DMARDs, providing clinical benefit in4-6 weeks. As the drug is retained in the body for2 years, elimination...