... J M, Thomas S H L2001 Anti-TNF agents for rheumatoid arthritis.British Journal of Clinical Pharmacology 51: 201-208Sneader W 2000 The discovery of aspirin: areappraisal. British ... all being important.SYMPTOMATICTREATMENTNSAIDs provide much symptomatic relief andimprove clinical indicators of disease activity such asjoint swelling, but do not improve its outcome, ... first choiceDMARD.AzathioprineAzathoiprine is metabolised to 6-mercaptopurine(see p. 6 08), which is responsible for many, but notall, of its actions as an inhibitor of purine...