Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 3) ppt

Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 13) ppt

Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 13) ppt

... the clinical diagnosis, but no safe assumption can be made as to its sensitivity to any one antimicrobial, e.g. tuberculosis. 3. The infecting organism is not identified by the clinical ... killing effect of a bactericidal drug. Such mutual antagonism of antimicrobials may be clinically important, but the matter is complex because of the multiple and changing...

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Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 14) pptx

Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 14) pptx

... drug-resistant tuberculosis (see p. 2 53). Inhibition of protein synthesis Aminoglycosides In the purposeful search that followed the demon- stration of the clinical efficacy of penicillin, ... 1997 Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implications. Clinical Microbiology Reviews 10: 781-791 Diekema D J, Jones R N...

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Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 16) pptx

Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 16) pptx

... mosquito (site 4). In summary, drugs may be selected for: • treatment of clinical attacks • prevention of clinical attacks • radical cure. Drugs used for malaria, and their principal actions ... to AmBisome if the patient's renal function deteriorates. Further clinical trials are needed to establish the best clinically and cost effective ways to use...

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Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 18) ppt

Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 18) ppt

... of allergy to drugs, e.g. metabolism, combination with protein, fatal anaphylaxis (see p. 1 43). Treatment. Remove the cause; use cooling appli- cations and antipruritics; use a histamine ... the drug is withdrawn. Some drugs, notably NSAIDs, induce a 'pseudoporphyria', clinically resembling porphyria cutanea tarda and presenting with skin fragility, bliste...

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Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 20) ppt

Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 20) ppt

... and extradurally. They diffuse into the spinal cord and act on its opioid receptors (see p. 3 33); they are highly effective in skilled hands for postsurgical and intractable pain. Respiratory ... for this reason is not used for prolonged infusion; single bolus doses cause short- lived, clinically insignificant adrenocortical sup- pression. Despite all these disadv...

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Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 21A) pptx

Tài liệu CLINICAL PHARMACOLOGY 2003 (PART 21A) pptx

... of limited value clinically as they are very heterogenous. A classification by receptor binding profiles is likely to emerge with growing evidence on the clinical importance ... the basis of the side chain since these tend to predict adverse effect profiles (Table 19 .3). The continuing search for greater efficacy and better tolerability led researchers and...

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