Báo cáo y học: "Prion propagation in vitro: are we there yet"

... following lengthy incubation periods. However, synthetic prions were not able to transmit disease directly to wild type mice. To obtain infectivity in wild type mice, synthetic prions were Int. ... the propagation of infectivity.23 Cell-Lysate Conversion Assay Saborio et al. introduced a system termed the cell-lysate conversion assay.24 This method describes incubating lysate of Chi...

Ngày tải lên: 03/11/2012, 11:52

... vitro. These findings demonstrated that PG production by intrauterine tissues may be up-regulated by proinflammatory cytokines. Furthermore, an anti -in ammatory cytokine such as IL-10 inhibited the ... was shown by Western blotting analysis that Mn-SOD protein existed in the tissue and increased slightly during incubation; however, Cu/Zn-SOD protein was barely detectable under the analytical...

Ngày tải lên: 22/02/2014, 07:20

... incidents in thisregion. The purpose of this study was to find whether thisinstitution has achieved its primary tasks by analyzing itsregistry during January 1st 2006 until December 31st 2008.SettingAccording ... knowledge few, if any, have theregional responsibility for staff training by conducting dis-aster and disaster-related courses and training. Theinvolvement of the same people in...

Ngày tải lên: 25/10/2012, 09:56

... [57].Recognizing early symptoms of hepatic toxicity and dis-continuing treatment are important in optimizing recov-ery. Early symptoms of hepatic toxicity include apathy,malaise, fever, diminished ... metabo-lite syndrome), including carbamazepine, phenytoin,phenobarbital, and lamotrigine. The triad of hypersensi-tivity includes fever, rash and internal organ involvementwith onset of sy...

Ngày tải lên: 25/10/2012, 10:51

... treatment of traumatic brain injury, these technical improvements are valuable. Key words: Decompressive Craniectomy, Traumatic Brain Injury Introduction Decompressive craniectomy, which is performed ... in normal brain. An experimental PET-study in cats. Brain Res 2003;982:31-37. 37. Sakamoto S, Eguchi K, Kiura Y, et al. CT perfusion imaging in the syndrome of the sinking s...

Ngày tải lên: 25/10/2012, 11:40

... Vancomycin are used. Ex-tending this repertoire with newer antibiotics, espe-cially Linezolid, Daptomycin and Tigecyclin were introduced for PJI therapy. A valid rating for the newest (lipo)glycopeptides ... to a large number of different binding molecules. Espe-cially fibrinogen, extracellular matrix proteins and glycosaminoglycans, including fibronectin and laminin, are components of...

Ngày tải lên: 26/10/2012, 09:57

... heterozygous genotype and homozygous rare genotype separately whenever pos-sible (information available in at least two studies). In some cases, we combined the heterozygous genotype with the homozygous ... Gln/Gln genotype vs. Lys/Lys genotype). There was no interaction between smoking (smoking status, pack-years and duration) and the polymorphism [14, 19, 26, 27]. Although the L...

Ngày tải lên: 31/10/2012, 14:59

... investigated extensively. In gymnosperms, such as grand fir, terpenes are produced in resin ducts [2,3]. Their biosynthesis is induced upon wounding [4–6], indicating their role in the defence against bark beetle infestation. ... hexane. To investigate the linearity of the assays with time the enzymes were incubated for 0, 10, 20, 30, 45 and 60 min at 30 °C. For testing the pH optimum...

Ngày tải lên: 08/03/2014, 23:20

... Ca 2+ ] i spiking not by increasing the InsP 3 level but by potentiating InsP 3 receptor-mediated Ca 2+ release. This may explain why the Ca 2+ response with thimerosal is only partially inhibitable by P ... results indicate that both InsP 3 -generating (thrombin) and non- InsP 3 -generating (sulfhydryl reagents) agents cause irregular [Ca 2+ ] i spiking in platelets. The thrombin-induced s...

Ngày tải lên: 17/03/2014, 17:20

... uncertainty in one area will not block conclusions in others. For instance, the pro- cessing of consonants is not derailed by uncertainty about vowels, so information about underlying consonants ... search by exploiting this aspect of informa- tion structure. We have begun exploring such methods in a prelim- inary and approximate way by implementing a modular, non-searching con...

Ngày tải lên: 17/03/2014, 20:20