Báo cáo y học: "Transporter Molecules influence the Gene Expression in HeLa Cells"
Báo cáo y học: "Transporter Molecules influence the Gene Expression in HeLa Cells"
... impact on the gene expression patterns, when analyzing the efficacy and the genetic consequences of targeted gene therapy in vitro (and in vivo). Microarray Study Differential Gene Expression ... 2 min respectively. BeadArray gene expression analysis We used an integrated genomics profiling and computational biology based strategy to identify the key genes and gene...
Ngày tải lên: 03/11/2012, 11:44
Báo cáo y học: " Low concentration of ethanol induce apoptosis in HepG2 cells: role of various signal transduction pathways"
... after its initial effect on protein kinases phosphorylation. The most strikingly and novel finding obtained hereby was the strong inhibition of the GPCR signaling pathway induced mainly by increased ... [36]. The kinase IKKα plays a key step in the activation of NFκB [37]. Our data demonstrated that ethanol inhibits the anti-apoptotic effect of the NFκB signaling pathway by re...
Ngày tải lên: 31/10/2012, 15:37
Báo cáo khoa học: Enzymatic features of the glucose metabolism in tumor cells ppt
... product, the c-myc binding protein (MBP-1) lacking enzymatic activity. These divergent a-enolase gene products are interlinked: expression of the glycolytic enzyme a-enolase is upregu- lated by c-myc, ... polypeptides of the respira- tory chain). Mutations of the nDNA hitting genes involved in mitochondria biogenesis such as, for exam- ple, enzymes of the cardiolipin synthesiz...
Ngày tải lên: 14/03/2014, 23:20
Báo cáo khoa học: Oxygen control of nif gene expression in Klebsiella pneumoniae depends on NifL reduction at the cytoplasmic membrane by electrons derived from the reduced quinone pool doc
... transformed into RAS46 and recombinant strains carrying the chromosomally inserted plasmid (by means of single homologous recombination) were identified by their resistance to tetracycline and their inability ... Germany). In general, mutant strains of the streptomycin resistant K. pneumoniae UN4495 strain (RAS46) were constructed using the allelic exchange system developed by Skorupsk...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Neurotrophic signalling pathway triggered by prosaposin in PC12 cells occurs through lipid rafts doc
... protein (LRP-1) [8]. The presence of lipid-binding domains in prosaposin and saposins has been well demonstrated [9], and a Keywords lipid domains; PC12 cells; prosaposin; rafts; sphingosine kinase Correspondence R. ... revealed by scanning confocal microscopy and linear sucrose gradient analysis. In these cells, prosaposin is able to induce extracellular signal-regulated kinase phospho...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo y học: "Users' guides to the medical literature: how to use an article about mortality in a humanitarian emergency"
... in mind when reading amortality survey to determine the validity of the study and the applicability of the findings to theirsettings.Public health scenarioYou are a physician working for an international ... mortality isoccurring, by comparing the observed mortality rate withthe best available estimate of the baseline mortality rate inthe pre-war period, either by subtraction or...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: "Anticancer Activity of the PR Domain of Tumor Suppressor RIZ1"
... Biol Ther 2003; 2: 491-9. 16. Huang S, Shao G, Liu L. The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in ... domain of human retinoblastoma pro-tein-binding zinc finger protein 1 (RIZ1). Int J Mol Sci 2008; 9: 943-50. 21. Chen L, Ling B, Alcorn J, Yang J. Analysis of the expression of human N-myri...
Ngày tải lên: 25/10/2012, 11:15
Báo cáo y học: " Experimental ablation of the pancreas with high intensity focused ultrasound (HIFU) in a porcine model"
... parameters In the present study, the amylase levels in the serum and urine were increased in the first 3 days and the first 5 days after HIFU ablation, respectively. But no significant ... efficacy and safety. To evaluate the rela-tionship between HIFU energy and pancreas histol-ogy, a preclinical in vivo study was conducted in swine demons t rat ing the feasibility .....
Ngày tải lên: 25/10/2012, 11:18
Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"
... Devine et al intravenously injected autologous and allogeneic MSC into baboons, and no toxic reactions were observed during 1-year follow-up [41]. Another intravenously injected allogeneic ... imaging system is a real-time imaging system which can be used to ob-serve the distribution of cells in living animals in a real time pattern. In the imaging system, ... gradually decreased, a...
Ngày tải lên: 25/10/2012, 11:18
Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"
... predominant presenting complaint was abdominal pain (8/18). The rest of the patients were asymptomatic and tumors were de-tected incidentally during routine physical examina-tion. All these patients ... (SPN), the experience with the management of disseminated disease is very limited in the literature6, therefore, attention to the therapy strategy of this neoplasm in the fut...
Ngày tải lên: 25/10/2012, 11:40