Ngày tải lên: 26/10/2012, 10:03
... inhibits allosterically the b inding of the s corpion a-tox in, Aah-II, to rat brain synaptosomes [27,28]. To examine the similarity in binding to receptor site-3 between scorpion a-toxins and d-ACTXs, we analysed ... of PbTx-1 on 125 I-labelled d-ACTX-Hv1a binding to rat brain synaptosomes. Simi- larly to the effect of PbTx-1 on Aah-II binding [27,28], this brevetox...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: Monoterpene biosynthesis in lemon (Citrus limon) cDNA isolation and functional analysis of four monoterpene synthases pot
... Germany; 3 Laboratory of Plant Physiology, Wageningen University, the Netherlands Citrus limon possesses a high content and large variety of monoterpenoids, especially in the glands of the fruit flavedo. The ... B93 and D85. The identity of the sequences of B93 and D85 up to the RRX 8 W motif is 90%. They are very different from the targeting signals of C62...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx
... by multiplying the derivative of the ®tted curve at each point of the graph with the quotient of the respective x /y coordinates. At wild-type level of supercoiling a n elasti- city coecient of ... made in the analysis (i.e. that topoisomerase I and DNA gyrase are the main contributors to the steady state wild-type level of supercoiling) is correct within th...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: LRP130, a protein containing nine pentatricopeptide repeat motifs, interacts with a single-stranded cytosine-rich sequence of mouse hypervariable minisatellite Pc-1 docx
... not bind to the double-stranded form, or to C5gg, indicating that mLRP130 binds to the single- stranded C-rich sequence in a sequence-dependent man- ner. These results led us to the hypothesis ... Additionally, formation of the I-tetraplex structure by the C-rich strand of the telomere and insulin-VNTR has also been reported [38,40]. Recently, we have reported that...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: " WT1 PEPTIDE VACCINATION IN COMBINATION WITH IMATINIB THERAPY FOR A PATIENT WITH CML IN THE CHRONIC PHASE"
Ngày tải lên: 26/10/2012, 09:39
Tài liệu Báo cáo Y học: Transactivation domains are not functionally conserved between vertebrate and invertebrate serum response factors potx
... of SRF cofactors. Some of these cofactors are tissue-specific, as the muscular Nkx2.5 [15], GATA-4 [16] or myocardin [17] transcription factors. Other cofactors are regulated by growth-factor transduction ... regions did not acti- vate CA promoter and strongly repressed the c-fos promoter, independently of the origin of the N-terminal region. The lack of activity of th...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: Two different E2F6 proteins generated by alternative splicing and internal translation initiation ppt
... Exon2-mut-luc), and compared its activity to the activity of Exon2-luc in transient transfection assays. The mutation led to complete loss of activity in these assays, indicating that the integrity of the ... times lower than that of Exon1-luc and Exon3-luc (Fig. 4B). However, activity of Exon2-luc was still up to more than 1000 times higher than the activity of...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Boar salivary lipocalin Three-dimensional X-ray structure and androstenol/androstenone docking simulations pot
... boar’s phero- mones, 5a-androst-16-en-3-one and 5a-androst-16-en-3-ol [2]. The affinity of SAL for 5a-androst-16-en-3-one has been determined using fluorescence by competition with 1-aminoanthracene ... affinity for 1-amino-anthracene, for androstenone, and for a group of odors such as 3,7-dimethyl-1-octanol, 2-phenyl ethanol, 2-isobutyl-3-methoxypyrazine has been assayed by fluorescenc...
Ngày tải lên: 17/03/2014, 17:20