Báo cáo y học: " Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis"
Báo cáo y học: " Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis"
... Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis Zhong Zhao1,2, Dale J. Lange1,3 ,Lap Ho1,2, Sara Bonini1,2, ... immunocyto-chemically revealed that Vgf immunoreactive material in spinal cord motorneurons is already decreased in ~75 day old asymptomat...
Ngày tải lên: 03/11/2012, 10:52
Báo cáo y học: "Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units"
... between 28% and 54%.Eosinopenia was a sepsis marker in our study. The study by Giland colleagues in a department of internal medicine showedthat an inflammatory syndrome associated with an eosinophilcount ... mg/dl.Statistical analysesData are presented as the mean ± standard deviation for vari-ables with a normal distribution, and as the median and inter-quartile range for va...
Ngày tải lên: 25/10/2012, 10:35
Báo cáo Y học: Structural and serological relatedness of the O-antigens of Proteus penneri 1 and 4 from a novel Proteus serogroup O72 pptx
... polysaccharides in a yield of 20% of the LPS mass. Rabbit antisera and serological assays Polyclonal O-antisera were obtained by immunization of rabbits with heat-inactivated bacteria of P. penneri 1and4 according ... etrasaccharide (strain 1 ) and pentasac- charide (strain 4) repeating units of the polysaccharides were established: In the polysaccharide of P. penneri strain 4, glycos...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: The Emery–Dreifuss muscular dystrophy associated-protein emerin is phosphorylated on serine 49 by protein kinase A pptx
... Professor. References 1 Nagano A, Koga R, Ogawa M, Kurano Y, Kawada J, Okada R, Hayashi YK, Tsukahara T & Arahata K (1996) Emerin deficiency at the nuclear membrane in patients with Emery–Dreifuss muscular dystrophy. ... A (PKA) and we have confirmed this using an in vitro protein kinase assay. Potential signal transduction pathways that could be involved in phos- phorylating...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity pot
... constant level of intact IGFBP-4 in murine pregnancy was caused by an increase in synthesis along with increased proteolysis. The presence of PAPP -A mRNA in all murine tissues analyzed parallels the ... USA Murine pregnancy -associated plasma protein -A (PAPP -A) cDNA encoding a 1545 amino-acid protein has been cloned. We have also identified and cloned cDNA that encodes a no...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo Y học: Functional studies of the Synechocystis phycobilisomes organization by high performance liquid chromatography on line with a mass spectrometer docx
... chromatogram abundant in hydrophilic proteins such as linkers and a significant amount of a- and b-phycocyan ins, and only traces of the allophycocyanins. On the contrary, HPLC a nalysis of bands 2–5 ... contained less b-phycocyanin; this only had a marked effect on band 5, the heaviest one, consistent with th e idea that this band contains mainly b-phycocyanins. Probably during nit...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: Identification of novel membrane proteins by searching for patterns in hydropathy profiles potx
... profiles are displayed in a convenient format. This approach can be used to search for new members of a family or functional class of membrane protein. It can assist with functional analysis, and may ... Most membrane -associated domains produce an easily identified peak in the hydropathy profile of the polypeptide. Standard software tools are available that can identify the putative...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: Ruk is ubiquitinated but not degraded by the proteasome ppt
... form a family of related proteins harboring several highly conserved domains, such as an N-terminal variant SH2 domain, a RING finger and a C-terminal proline-rich domain containing potential tyro- sine ... proteolysis, causing an accumulation of proteins that are usually degraded by this pathway [22]. In contrast to lactacystine, which is a highly specific proteasomal inhibitor [...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN Design of a potent endozepine antagonist pot
... respectively, as an agonist and an antagonist of the metabotropic receptor which mediates the ODN-induced [Ca 21 ] i increase in rat astrocytes. It has been previously shown that a vacant C-terminal carboxylic ... processes by analytical RP-HPLC revealed that the N a -Fmoc group was not totally stable in reductive media. This observation was at variance with the data reported by Car...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo y học: "Weight loss, leukopenia and thrombocytopenia associated with sustained virologic response to Hepatitis C treatmen"
... and categorical variables for the pre-dictors of SVR were compared by using logistic re-gression and multivariate analysis (categorical data) as displayed in Table 3. In multivariate analysis, ... continuous data was evaluated by the O’Brien test for homogenicity of variances. When necessary, an appropriate normalizing or variance stabilizing transformation was applied. Analysis of varian...
Ngày tải lên: 26/10/2012, 09:39