Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"

Báo cáo Y học: Herbaspirillum seropedicae signal transduction protein PII is structurally similar to the enteric GlnK potx

Báo cáo Y học: Herbaspirillum seropedicae signal transduction protein PII is structurally similar to the enteric GlnK potx

... the central cavity of the HsPII trimer, with the a helices at the periphery of the molecule (Fig. 1A). The bottom edge of the central cavity is negatively charged (Fig. 2B, part i) owing to the ... by Phe in EcPII and Ala in EcGlnK. The entrance from the top is restricted by Thr31, whose lateral chain is oriented to the interior of the cavity. The interio...
Ngày tải lên : 24/03/2014, 04:21
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Báo cáo y học: "Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units"

Báo cáo y học: "Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units"

... score3 (1 to 8) 0 (0 to 2) 1 (0 to 4) 3 (1 to 6) 0.002ICU length of stay (days) 5 (3 to 10) 3 (2 to 5) 6 (2 to 10) 7 (4 to 11) 0.001Sites of infection (n (%))Respiratory tract 72 (60)Urinary tract ... participated in the acquisi-tion of data. AZ participated in the coordination of the study.AAZ participated in the design of the study, and performed thestati...
Ngày tải lên : 25/10/2012, 10:35
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Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"

Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"

... Assessing Applicability to Human Germline Gene Therapy An ideal gene transfer system in the context of human germline gene therapy would have the following features: (a) the ability to deliver transgenes ... able to provide all of features (a-g) above. Indeed, some gene transfer systems are so thoroughly unsuited to human germline gene therapy that th...
Ngày tải lên : 03/11/2012, 10:01
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Báo cáo y học: "Antiviral therapy of HCV in the cirrhotic and transplant candidate"

Báo cáo y học: "Antiviral therapy of HCV in the cirrhotic and transplant candidate"

... cytopenias. The use of these agents is costly and has not been studied rigorously in a randomized controlled format to assess their value and impact on efficacy of therapy although they are now widely ... combination therapy. Hepatology 2004;40:1450-8. 15. Crippin JS, McCashland T, Terrault N, Sheiner P, Charlton MR. A pilot study of the tolerability and efficacy of antiviral...
Ngày tải lên : 31/10/2012, 17:11
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Báo cáo Y học: Cloning, chromosomal localization and characterization of the murine mucin gene orthologous to human MUC4 pdf

Báo cáo Y học: Cloning, chromosomal localization and characterization of the murine mucin gene orthologous to human MUC4 pdf

... sequence of the 3¢ part of the gene encompassing 17 kb. Three poly(A) signals were found after the stop codon. Analysis of the four cosmid clones by PCR revealed that they do not contain any sequence ... Contigs analysis of the Human Genome Project did not reveal any other mucin on chromosome 3q29 and, interestingly, our analysis allowed the determination of the ge...
Ngày tải lên : 08/03/2014, 23:20
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Báo cáo Y học: Novel regulatory regions found downstream of the rat B29/Ig-b gene docx

Báo cáo Y học: Novel regulatory regions found downstream of the rat B29/Ig-b gene docx

... activity to that of the B29-P promoter alone. The 30-bp deletions (4193 to 4222) unrelated to the footprinted region had activity similar to that of the control. The sequence responsible for the ... flanking genes may change. Recently, enhance- ment of H3 and H4 histone acetylation was observed from the promoter region of human GH gene to the upstream regi...
Ngày tải lên : 24/03/2014, 03:21
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Báo cáo y học: "Ozone Therapy and Hyperbaric Oxygen Treatment in Lung Injury in Septic Rats"

Báo cáo y học: "Ozone Therapy and Hyperbaric Oxygen Treatment in Lung Injury in Septic Rats"

... proinflammatory cytokine levels, IL-1β and TNF-α, were found to be ameliorated by the adjuvant use of HBO and OT in the lung tissue when compared with the antibiotherapy only group. Histologic ... prevent the possible effects of biological rhythm. Sample collection At the end of 5th day of the study, general anaesthesia was administered to immobilize the...
Ngày tải lên : 25/10/2012, 11:18
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Báo cáo y học: "Parvovirus B19 Genotype Specific Amino Acid Substitution in NS1 Reduces the Protein’s Cytotoxicity in Culture"

Báo cáo y học: "Parvovirus B19 Genotype Specific Amino Acid Substitution in NS1 Reduces the Protein’s Cytotoxicity in Culture"

... translation of B19 NS1 (18, 34), has lead us to examine the potential role of B19 NS1 in direct hepatocyte cytotoxicity. Our laboratory pre-viously demonstrated that B19 NS1 caused apoptosis in ... suicide, previously reported to be the mechanism of B19 NS1-induced cytotoxicity (34, 35). Further confirmation for the reduction of apop-tosis in the PathI transduced populat...
Ngày tải lên : 26/10/2012, 09:32
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Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot

Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot

... disease. Unfortunately the quality of s ome of these syn uclein ROA spectra i s generally not as good as that of the caseins d ue in part to the high concentrations of buffer salts. Figure 3 shows the backscattered ... 6 . The X-ray crystal structure 1 pi2 reveals that the /,w angles of most of the residues of the Bowman±Birk inhibitor are distributed fairly ev...
Ngày tải lên : 21/02/2014, 15:20
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Tài liệu Báo cáo Y học: Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells docx

Tài liệu Báo cáo Y học: Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells docx

... Perhaps, the negatively charged carboxyl moiety of TS is important for upregulation of PKC. Recently, Neuzil et al. reported the opposite findings to ours. They proposed that TS-induced apoptosis ... apoptosis in hepatopoietic and cancer cell lines is caused by the prevention of PKC activity due to activation of PP2A, similar to a-T activation of PP2A [13]. The reason f...
Ngày tải lên : 22/02/2014, 04:20
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