... diagnosis of general medical conditions may bedelayed. As the physician with the most (and often theonly) contact with these patients, psychiatrists need to bevigilant in detecting early signs and symptoms ... must be aware of the effects of psychotropicson the kidneys, as well the effects of decreased renal func-tioning on the pharmacokinetics of medicationsprescri...
Ngày tải lên: 25/10/2012, 10:51
... located in the portion of body or tail of the pancreas. For tumors of SPT located in the neck and body of the pancreas, resection of the mid-portion of the pancreas and the mass with preserving the ... Shandong University, Jinan Shandong, China; 2. Department of Rehabilitation, Shandong Provincial Hospital affiliated to Shandong University, Jinan Shandong, Ch...
Ngày tải lên: 25/10/2012, 11:40
Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf
... cleavage of mRNA or by inhibi- tion of protein synthesis. On the one hand, computa- tional algorithms have been widely used to predict miRNA targets. On the other, gene expression profil- ing analysis ... confirm the postulation, we checked the regulatory effects of miR-23a on the expression of IL6R by RT-PCR and western blot, and found an inverse correlation bet...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells docx
... permeability of the Fe–chelator complex. In view of the similar efficacy of the multidentate pyridinones to DFO, further experiments were conducted using a wider range of pyridinones on normal and Fe-loaded ... C., Hoffbrand, A.V., Kosaryan, M., Olivieri, N.F., Tondury, P. & Wonke, B. (1995) Results of long-term deferiprone (L1) therapy: a report by the Inter- national...
Ngày tải lên: 20/02/2014, 11:20
Báo cáo y học: "Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units"
... purposes)Authors' contributionsKA and IK contributed equally to the work. KA and IK draftedthe manuscript and participated in the acquisition of data andthe study design. JB participated in the acquisition of ... draft the manuscript, and participated in the acquisi-tion of data. AZ participated in the coordination of the study.AAZ participated in the desi...
Ngày tải lên: 25/10/2012, 10:35
Báo cáo y học: "HLA-DR regulation and the influence of GM-CSF on transcription, surface expression and shedding
... University of Leeds, and PhD in Immunology from University of Liverpool, where she worked on the expression of HLA-DR and the characterisation of the monocyte in patients with sepsis. She is currently ... is a glycosylated cell surface transmembrane protein expressed on antigen-presenting cells and constitutively expressed on monocytes. Expression of HLA-DR b...
Ngày tải lên: 03/11/2012, 09:57
Báo cáo y học: "Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis"
... authors, year of publication, ethnic group of the study popula-tion, source of control population, number of geno-typed cases and controls, crude odds ratio (OR) and the method for quality control of ... located in the vicinity of the translation initiation codon, it may alter translation efficiency. The nearby proximal nucleo-tides to the AUG initiation codon are...
Ngày tải lên: 31/10/2012, 14:59
Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot
... acidic conditions are unlikely to alter the conformation signi®- cantly. The backscattered Raman and R OA spectra of the wild-type and mutant tau46 are shown as the top and bottom pairs, respectively, ... onformational elements are similar and hence that the structures of the caseins, synucleins and tau may be envisaged as more open, hydrated, longer-chain (and nong...
Ngày tải lên: 21/02/2014, 15:20
Tài liệu Báo cáo Y học: Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells docx
... production. The degrees of inhibition of NO production with Ro31-2880 and GF109203X were approximately 70 and 30%, respectively. Effects of TS on the amount of PKCa We further examined the effects of ... examined only TS has an amphiphilic structure of the polar carboxyl moiety and the hydrophobic isoprene moiety. The enhancing effect of TS on LPS/IFN-induc...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells pdf
... [32]. Recently, the expression and the activity of different isoforms of acyl-CoA synthetases was described in the rat liver [37,38]. In addition, a report by Kang [39] implicates the participation of ... compartment of the cell upon hormone treatment. Taken together the results shown here demonstrate the critical role of acyl-CoA synthetases and thioesterases in...
Ngày tải lên: 08/03/2014, 09:20