Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
... rights reserved Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects Research ... as the evaluation of methylenetetrahdrofolate reductase gene mutation in Egyptian patients with coronary heart disease; evaluation of the...
Ngày tải lên: 03/11/2012, 09:49
Báo cáo y học: "Weight loss, leukopenia and thrombocytopenia associated with sustained virologic response to Hepatitis C treatmen"
... prevent physicians from continuing their patients on interferon therapy or reducing dosage (28, 29). A comparison of outcome by the approach of re-ducing interferon and/or ribavirin versus use of growth ... combined pegylated interferon alfa-2a or alfa-2b plus ribavirin. Genotypes of HCV were defined using the Bayer TRUGENE HCV Genotyping Test. Serum concentra-tion of HCV RNA wa...
Ngày tải lên: 26/10/2012, 09:39
Tài liệu Báo cáo Y học: Ornithine decarboxylase-antizyme is rapidly degraded through a mechanism that requires functional ubiquitin-dependent proteolytic activity pot
... precursors. In this biosynthesis pathway ornithine is decarboxylated to form putrescine by the action of ornithine decarboxylase (ODC, EC 4.1.1.17). Next an aminopropyl group generated by the action of S-adenosylmethionine ... illumination. RESULTS Antizyme is rapidly degraded by the action of the 26S proteasome While it is clear that interaction with antizyme is req...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: DAP kinase activity is critical for C2-ceramide-induced apoptosis in PC12 cells ppt
... (pro line 277 to leucine 323) containing the calmodulin-binding domain. In the K42A-DK mutant, a lysine residue at position 42 in t he kinase domain (asterisk) is replaced by an a lanine. The D ... kinase [20±22], a lso phosphorylates the regulatory light chain of myosin II the phosphorylation sites being threonine 18 and serine 1 9 [22]. In this study, the synthetic pep...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo Y học: Soluble guanylate cyclase is allosterically inhibited by direct interaction with 2-substituted adenine nucleotides doc
... and catalytic domains of pGCs is mediated by the KHD in the cytoplasm, which serves as a constitutive repressor of the catalytic domain. This domain contains the 11 subdomains characteristic of protein ... C 1 –C 2 interface of the catalytic domain of adenylate cyclase do not exist in guanylate cyclases. Thus, the site of adenine nucleotide binding and allosteric...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: ik3-1/Cables is a substrate for cyclin-dependent kinase 3 (cdk 3) pdf
... phase progression is regulated by G1 cyclin and cyclin-dependent kinases (cdks). Cdk4 or cdk6 is associated with D-type cyclins while cdk2 binds to cyclin E or cyclin A to become an independent and ... phosphorylated by cyclin A/cdk2, cyclin E/cdk2, cyclin A/cdk3 or cyclin E/cdk3 which is produced in the baculoviral system We initially tested a hypothesis that p70 ik3-1 might...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo y học: " A Practical Approach to Managing Patients with HCV Infection"
... identify the possible timing of the infection or the duration of the liver disease include: prior history of injection drug use, former history of transfusion of blood products, unexplained history ... thoroughly reviewed by Drs. Chen and Morgan in this issue. Knowing the natural history of HCV infection is important in the management of patients with chronic...
Ngày tải lên: 02/11/2012, 09:51
Báo cáo y học: "TPO, but not soluble-IL-6 receptor, levels increase after anagrelide treatment of thrombocythemia in chronic myeloproliferative disorders"
... receptors Introduction One of the clinical challenges in chronic mye-loproliferative disorders (MPD) is thrombocythemia, always present in essential thrombocythemia (ET) and often in polycythemia ... thereby reducing megakaryocyte size and ploidy, and disrupting or preventing full megakaryocyte matura-tion. However, little is known of the interaction of anagrelide with c...
Ngày tải lên: 03/11/2012, 10:52
Báo cáo Y học: Matrilysin (matrix metalloprotease-7) cleaves membrane-bound annexin II and enhances binding of tissue-type plasminogen activator to cancer cell surfaces docx
... Serotonin (5-hydroxytryptamine) interacts with N-acetylneuraminic acid, which is often contained in glycolipids and glycoproteins on the cell surface [24]. We examined the synergistic effects of ... Pannekoek H (1986) On the interaction of the finger and the krin- gle-2 domain of tissue-type plasminogen activator with fibrin. Inhibition of kringle-2 binding to fibrin by...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermine pdf
... pools of putres- cine, spermidine and spermine by down-regulating the activity of the polyamine biosynthetic enzymes a nd up-regu- lating the activity of the catabolic enzyme spermidine/ spermine ... analysis. Th e cells were sonicatedin50m M Tris/HCl (pH 7.5) containing 0.25 M sucrose. The a ctivity of SSAT in the sonicate was deter- mined by measuring the synthesis...
Ngày tải lên: 17/03/2014, 23:20