Báo cáo y học: "Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary"
... Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary Corresponding address: Andrew E. Czeizel Foundation for the Community Control of Hereditary Diseases, 1148 Budapest, ... characteristics of the study population, etc. In Hungary the total prevalence of congenital abnormalities was 66.83 per 1000 informative offspring in the...
Ngày tải lên: 02/11/2012, 11:12
... biofilms, culturing the sonication fluid is likely to raise sensitivity of cultures significantly. Especially in patients having received antimicrobial therapy within 14 days before culture the ... criteria, among them Vancomycin seems to be the most widely evaluated one. Vancomycin is one of the antibiotics with intracellular bactericidal activity and therefore should cover SCVs...
Ngày tải lên: 26/10/2012, 09:53
... several examples of theory being misled by mistaken data. Indeed, early reports of SMGT were compared with the (then contemporary) claims of “cold fusion” in physics [36]. By contrast, the second possible ... microscope, the needle is guided through the cytoplasm towards one of the zygote’s pronuclei. A nanolitre quantity of DNA solution is injected, bringing typically two...
Ngày tải lên: 03/11/2012, 10:01
Tài liệu Báo cáo khoa học: "Methods for the Qualitative Evaluation of Lexical Association Measures" doc
... identification: (i) the syntactic homogeneity of the base data, i.e., whether the set of candidate data consists only of adjective-noun, noun-verb, etc. pairs or whether different types of word combinations ... to the recall curves (Figures 3 and 4), we find: (i) Examination of 50% of the data in the SLs leads to identification of between 75% (AdjN) and 80% (PNV) of...
Ngày tải lên: 20/02/2014, 18:20
Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... these enzymes catalyse an hydrolytic reaction with production of urea. The question arises therefore as to whether a similar or identical mechanism is involved in catalysis by these enzymes, which apparently ... we conclude that the lower activity of the mutant may be ascribed to the loss of an acceptor hydrogen bond to a metal-bound hydroxide, as a consequence of replacement...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2C-methyl-D -erythritol 2,4-cyclodiphosphate in plants docx
... 2C-methyl- D-erythritol 4-phosphate can be converted into a cyclic diphosphate by the consecutive action of 4-diphosphocytidyl-2C-methyl- D- erythritol synthase, 4-diphosphocytidyl-2C-methyl- D-erythritol kinase ... the enzyme in D 2 O [54]; a rapid exchange was detected for the C-4 hydrogens and one of C-2 hydrogens of IPP as well as for the (E)-methyl group of DMAPP, fol...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot
... particle density of the polydisperse sol- utes. For the functional dependence between the density and molar mass of the fractionated emulsion particles, we assumed a spherical monolayer of Myr 2 Gro-PCho surrounding ... high-affinity ligand for a number of cell surface receptors, thereby mediating the uptake of cholesterol and other complex lipids into the cell [12,13...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo khoa học: Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen pptx
... oxygen sensor in human cells; however, the underlying kinetic basis of the oxygen-sensing function of prolyl hydroxylase domain 2 is unclear. We report analyses of the reaction of prolyl hydroxylase ... Department of Chemistry and Oxford Centre for Integrative Systems Biology, Oxford, UK 2 Department of Chemistry and Department of Biochemistry and Molecular Biology, The...
Ngày tải lên: 23/03/2014, 03:20
Báo cáo khoa học: Principles behind the multifarious control of signal transduction ERK phosphorylation and kinase/phosphatase control potx
... drug, or the occurrence of mutations affecting the control by one enzyme, will therefore almost always interfere with the regulation of the signal transduction pathway by all regulatory mechanisms, ... envi- ronment of the system is constant i.e. any external change such as the addition of EGF should have occurred at or slightly before t ¼ 0. The equation then defines...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo y học: "Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections"
... values .The development of sepsis from a localized infection isa dynamic continuum and in the majority a sequelae ofCAP [54]. The severity of a disease determines the con-sumption of costly and ... levels may mirrorboth, the inflammatory cytokine response correlatedwith the severity of infection, as well as the presence ofdisease-relevant comorbidities, namely heart failu...
Ngày tải lên: 25/10/2012, 10:02