Báo cáo y học: "Hepatitis C Virus (HCV) Infection and Hepatic Steatosis"
... directly injure the liver but it rather triggers an HCV-specific lymphoproliferation. Through profuse cytokine production and also a direct cytopathic effect, these T cells result in hepatocyte ... distribution and size of the lipid accumulation within the hepatocytes. Microvesicular steatosis that is seen in Reye’s syndrome and Acute Fatty Liver Disease of Pregnancy occurs due to dysfu...
Ngày tải lên: 02/11/2012, 09:51
... therapy. Virological tools include serological assays for anti-HCV antibody detection and serological determination of the HCV genotype, and molecular assays that detect and quantify HCV RNA and ... (PCR), “real-time” PCR or TMA [5]. HCV RNA is extracted and reverse transcribed into a double stranded complementary DNA (cDNA), which is subsequently processed into a cyclic enzymatic r...
Ngày tải lên: 02/11/2012, 09:56
... HBV infection, probably including latent infection, may play an important role in carcinogenesis in the patients with HCV infection. Table 2. Coinfection with HBV and HCV and risk of HCC HCC case ... HCC. What’s the combined effect of HBV and HCV coinfection on HCC? Accumulated epidemiological data suggested that coinfection with HBV and HCV could increase the risk for development...
Ngày tải lên: 02/11/2012, 09:51
Báo cáo y học: "Hepatitis B Virus e Antigen Variants"
... large and small envelope proteins have glycosylated and nonglycosylated versions, while the middle protein has monoglycosylated and doubly glycosylated forms. 3. How does anti-HBe immunity clear ... either directly or indirectly through the immune response. When massive liver damage occurs during acute infection, fulminant hepatitis may ensue. When such damage occurs during chronic in...
Ngày tải lên: 03/11/2012, 09:46
Báo cáo y học: "Treatment of Chronic HCV Infection in Special Populations."
... 5. Cirrhotics Treatment of non-decompensated cirrhotics is important since they have reduced survival, increased incidence of HCC and progression to a decompensated state with ascites and GI ... Influence of human immunodeficiency virus infection on the course of hepatitis C virus infection: a meta- analysis. Clin Infect Dis. 2001;33:562-569. Int. J. Med. Sci. 2006, 3 7317. Lind...
Ngày tải lên: 02/11/2012, 09:48
Báo cáo y học: "Epidemiology of Hepatitis C Virus (HCV) Infection"
... Danese V, Orlando G, Casciani CU. Hepatitis C virus infection in Italian kidney graft recipients. Changing risk factors and hepatitis C virus genotypes. Ital J Gastroenterology Hepatology 1997; 29:448-55. ... CDC: US. Viral Hepatitis C. http://www.cdc.gov/ncidod/diseases/hepatitis /c/ plan/Prev_Control.htm 84. Backmund M, Reimer J, Meyer K, Gerlach JT, Zachoval R. Hepatitis C...
Ngày tải lên: 02/11/2012, 09:56
Báo cáo y học: "The Natural History of Hepatitis C Virus (HCV) Infection"
... not clear the virus by 6 months, and chronic hepatitis develops. The rate of chronic HCV infection is affected by many factors, including the age at time of infection, gender, ethnicity, and ... directly from HCV infection or from the underlying immune stimulation caused by chronic infection. 8. Summary The chronic nature of hepatitis C infection influences the clinical approa...
Ngày tải lên: 02/11/2012, 09:56
Báo cáo y học: "Guest Editor’s Editorial: Advances in Managing Hepatitis C Virus (HCV) Infection (A Special Issue)"
... Moradpour, and Blum. Understanding HCV life cycle and the novel in vitro HCV replicating system will facilitate discovery of new anti-HCV drugs. Drs. Chevaliez and Pawlotsky describe the currently available ... serologic and molecular assays and their application in diagnosing HCV infection and monitoring HCV treatment. Understanding natural history of chronic HCV infection is...
Ngày tải lên: 02/11/2012, 10:09
Báo cáo y học: "Antiviral therapy of HCV in the cirrhotic and transplant candidate"
... therapy. Hepatology 2004;40:1450-8. 15. Crippin JS, McCashland T, Terrault N, Sheiner P, Charlton MR. A pilot study of the tolerability and efficacy of antiviral therapy in hepatitis C virus- infected ... those receiving interferon had a lower incidence of hepatocellular carcinoma and improved survival after 4 years. [4] A reduction in the risk for hepatocellular carcinoma in cirrhotic...
Ngày tải lên: 31/10/2012, 17:11
Báo cáo Y học: The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains pptx
... reaction primers used were 5¢-CTCAGGC TAGCAAGGGAAAAATAAACTTAGATC-3¢ (for D4 and DC-D4), 5¢-TCAGAGCTAGCAGTGGAGCCTATG TTGCACAG-3¢ (for DN-D4) and 5¢-TGGTGGTGG TGCTCGAGTGC-3¢. For the construction ... primer A (5¢-CGTTCTAGAGT GAGCAAGGGCGAGGAGCTG-3¢) and reverse primer B(5¢-ATCTACGTCGGCTAGCCTTGTACAGCTCGT CCATGCCGAG-3¢). The fragment was then ligated into the NheI site of the plasmid encodin...
Ngày tải lên: 23/03/2014, 21:20