Báo cáo y học: "Antiviral therapy of HCV in the cirrhotic and transplant candidate"
Báo cáo y học: "Antiviral therapy of HCV in the cirrhotic and transplant candidate"
... histological and survival benefits of interferon-based treatment. Insight into the efficacy of combination therapy with pegylated interferon and ribavirin in cirrhotic patients can be obtained from the ... rigorously in a randomized controlled format to assess their value and impact on efficacy of therapy although they are now widely used in patients receiving...
Ngày tải lên: 31/10/2012, 17:11
Báo cáo Y học: Identification of residues in the PXR ligand binding domain critical for species specific and constitutive activation docx
... of the human and mouse PXR ligand binding domains. By modeling the human PXR ligand binding domain we have identified and mutated two polar residues in the puta- tive ligand binding pocket which ... also to other receptors and further mutational and structural studies would be of great interest to further elucidate the dynamics of this part of the ligand binding dom...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo y học: "Complications after spacer implantation in the treatment of hip joint infections"
... stem. For loading of the bone cement, the combination of gentamicin and vancomycin was most frequently used followed by the combination of gentamicin and teicoplanin. Data about the antibiotic ... lower. The rate of spacer fractures in our series was approximately 10 %. Interestingly, the majority of the cases had no symptoms at all and only in 2 cases the...
Ngày tải lên: 26/10/2012, 09:53
Báo cáo y học: " Mutation Analysis of hCDC4 in AML Cells Identifies a New Intronic Polymorphis"
... at the DLMBC sequencing service (Dr. M. Meixner) in the Department of Biochemistry of the Charité, Berlin, Germany using the ABI PRISM Big Dye Terminator system (Applied Biosystems, Germany). ... mutations in the hCDC4 gene may not play a pivotal role in the pathogenesis of AML. Furthermore, we describe a new intronic polymorphism with high frequency in the intro...
Ngày tải lên: 31/10/2012, 16:49
Báo cáo Y học: Stimulated biosynthesis of flavins in Photobacterium phosphoreum IFO 13896 and the presence of complete rib operons in two species of luminous bacteria Sabu Kasai and Takumi Sumimoto pot
... Regulation of riboflavin biosynthesis in Bacillus subtilis is affected by the activity of the flavokinase/flavin adenine dinucleotide synthetase encoded by ribC.J.Bacteriol.180, 950–955. 5860 S. Kasai and ... identified in Bacillus subtilis [1]. Four enzymes participate in the synthesis of riboflavin from GTP and ribulose 5-phos- phate: pyrimidine deaminase/pyrimidine reductas...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo Y học: Thermal stability of peroxidase from the african oil palm tree Elaeis guineensis pdf
... y m i Þ 2 s ð2Þ where y i and y calc i are, respectively, the experimental and calculated values of C ex p ; y m i is the mean of the experimental values of C ex p ,andn is the number of points. Typical protein concentrations ... The reheating scan revealed that the only effect of the first scan was to decrease the peak intensity by a scale factor determin...
Ngày tải lên: 31/03/2014, 15:20
Tài liệu Báo cáo khoa học: Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein ppt
... SH2 domain; pYDEP, pYDED and pYDEV for the Nck SH2 domain; pYLNV, pYLNV, pYIN and pYMN for the Sem5 SH2 domain; pYMXM, pYVXM, pYIXM and pYEXM for the N-terminal SH2 domain of p85; pYXXM for the C-terminal ... C-terminal SH2 domain of p85; pYVIP, pYILI and pYILV for the C-terminal SH2 domain of PLC-r; pYELE, pYIDI and pYVDV for the N-terminal SH2 domain of PLC-r;...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: Lysosomal localization of GLUT8 in the testis – the EXXXLL motif of GLUT8 is sufficient for its intracellular sorting via AP1- and AP2-mediated interaction docx
... contributes to the endosomal ⁄ lysosomal targeting of GLUT8 in HeLa cells. The N-terminal domain of GLUT8 contains a transplantable internalization signal To determine the significance of the N-terminal ... finding that is in agreement with our in vitro binding data. Targeting of GLUT8 in the absence of AP1 and AP2 In order to investigate the contribution of...
Ngày tải lên: 16/03/2014, 02:20
Báo cáo khoa học: Dual role of Nbs1 in the ataxia telangiectasia mutateddependent DNA damage response ppt
... were found, in the second study, to be activated by the MRN complex only in the presence of DNA strand ends, resulting in the phosphorylation of downstream targets [42]. Furthermore, both Nbs1 and the ... forma- tion of MRN foci in cells exposed to IR, led to the hypothesis that the MRN complex functions in the sensing of DNA strand breakage and in the...
Ngày tải lên: 16/03/2014, 13:20
Báo cáo khoa học: Nuclear import of mPER3 in Xenopus oocytes and HeLa cells requires complex formation with mPER1 pdf
... import of mPER proteins in Xenopus oocytes The different individual murine PER and CRY pro- teins were generated by in vitro translation and injected into the cytoplasm of Xenopus oocytes. The kinetics ... the myc tag in tandem repeat were translated in vitro and injected into the cytoplasm of Xenopus oocytes. The nucleus and cytoplasm were separated manually...
Ngày tải lên: 30/03/2014, 20:20