Báo cáo y học: "Does Flavanol Intake Influence Mortality from Nitric Oxide-Dependent Processes

... www.medsci.org 2007 4(1):53-58 © Ivyspring International Publisher. All rights reserved Research Paper Does Flavanol Intake Influence Mortality from Nitric Oxide-Dependent Processes? Ischemic Heart Disease, ... causes of morbidity and mortality in much of the world, possibly reflects a very high flavanol intake and sustained nitric oxide synthesis activation. How-ever, there are many risk factors and ... The very high flavonoid intake taken by virtually all Kuna Indians residing in their indigenous home area, enjoying what is almost certainly the highest flavanoid intake of any community, has...

Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&

... much do you worry about your child missing adose of ADHD medication at school or when you arenot around?• How bothered are you by having to monitor yourchild's ADHD medication everyday?Child ... attention-deficit/hyperactivity disorder: Reliabil-ity and validity of a new instrument assessing perceiveddifficulties from a patient, parent and physician perspectiveover the day. Child Adolesc Psychiatry ... purposes)All study subjects were abruptly switched to MTS from astable dose of their previous oral ER-MPH. Motivation forparticipation in this study may have been prompted bylow efficacy, high prevalence...

Báo cáo Y học: Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation? ppt

... pathways, it seems to be dueto the low basal levels of activity of the pathways that existin unstimulated cells. This suggests that Mnk2a may beunusually readily phosphorylated and activated by ... Anthony, J.C., Kimball, S.R., Paul, G.L.,Layman, D.K. & Jeﬀerson, L.S. (1998) Availability of eIF4Eregulates skeletal muscle protein synthesis during recovery from exercise. Am. J. Physiol. ... recentstructural data place Ser209 too far away from Lys159 toform such an interaction, and biophysical studies indicatethat phosphorylation actually decreases the aﬃnity of eIF4Efor cap or capped RNA....

Báo cáo y học: "Antimicrobial Susceptibilities of Brucella Isolates from Various Clinical Speciemens"

... Van 100. Yil University, Department of Microbiology, 65100 Van, Turkey. 5. Refik Saydam National Hygiene Center, Department of Communicable Diseases Research, 06100 Ankara, Turkey.  Corresponding ... before the susceptibility tests. Antimicrobial susceptibility testing: Minimum inhibitory concentration (MIC) of doxycycline (DOX), rifampin (RIF), streptomycin (STR), tigecycline (TIG) and trimethoprim-sulfamethoxazole ... a:Doxycycline; b: Tigecycline; c: Trimethoprim/ sulfamethoxazole (only the trimethoprim portion of the 1/19 drug ratio is displayed); d:Streptomycin; e: Rifampin; f: not displayed in CLSI...

Tài liệu Báo cáo Y học: Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells docx

... antibody or rabbit anti-PKCpolyclonal antibody at 1 : 1000 dilution and anti-(rabbitIgG) Ig horseradish peroxidase conjugated antibody at1 : 5000 dilution as a primary antibody and a secondaryantibody, ... a-tocopheryl hemisuccinate (TS) as akey compound for clariﬁcation of the nonantioxidantfunction of a-T. TS is a naturally occurring amphiphiliccompound initially isolated from a green barley extract ... acid; BHA, butylhydroxyl anisol; ERK,extracellular signal-regulated kinase; IFN, interferon-c;iNOS,indu-cible nitric oxide synthase; JNK, c-Jun NH2-terminal kinase; LPS,lipopolysaccharide;...

Báo cáo Y học: Properties of group I allergens from grass pollen and their relation to cathepsin B, a member of the C1 family of cysteine proteinases pdf

... role for N-glycosylation in enzyme activationThe glycosylated rPhl p 1 b-expansins were very unstableduring expression in the methylotrophic yeast P. pastoris.The mutated, nonglycosylated allergen ... decreased(rPhl p 1 Q-like) enzymatic activity. As shown in Fig. 2C,deglycosylation of the allergen by N-glycosidase A indeedresulted in reduced proteolytic activity in zymogramscompared with rPhl ... N shows a muchmore pronounced proteolytic activity than the nonglycosylated aller-gen. (C) Eﬀect of enzymatic deglycosylation on rPhl p 1 N activity inzymograms. Expression supernatant was...

Báo cáo Y học: Conformational analysis of opacity proteins from Neisseria meningitidis ppt

... that are structurally related but highlypolymorphic. These proteins were originally identiﬁed ascolony-opacity-associated (Opa) proteins [1]. Opa proteinsappear to play a critical role in ... M., Meyer, T.F.& Gray-Owen, S.D. (2000) Carcinoembryonic antigen familyreceptor speciﬁcity of Neisseria meningitidis Opa variantsinﬂuences adherence to and invasion of proinﬂammatory cyto-kine-activated ... described by Davies et al. [22]. The expression ofwild-type OpaJ129 was determined by Western blottingusing monoclonal antibody 15-1-P5.5 [18]. The expressionof wild-type OpaB128 was determined by...

Báo cáo Y học: A Ca2+/CaM-dependent kinase from pea is stress regulated and in vitro phosphorylates a protein that binds to AtCaM5 promoter ppt

... immediately using a calibratedamount of Tris pH 7.5.In vitrophosphorylation assaysIn vitro phosphorylation assays were performed as describedearlier [21]. Brie y, protein eluted from the afﬁnity ... without p40 under any conditions andattempts to purify the kinase by gel elution gave a very lowyield and the eluted protein was highly labile.The 40-kDa protein is phosphorylated by PsCCaMKand ... Mueller Laboratory, Biology Department, ThePennsylvania State University, University Park, PA 16802, USA.Present address: Biochemistry Department, 117 Schweitzer Hall,University of Missouri,...

Báo cáo Y học: Cold adaptation of xylose isomerase from Thermus thermophilus through random PCR mutagenesis Gene cloning and protein characterization doc

... to nine times higher catalytic rateconstants (kcat)forD-xylose compared with the wild-typeenzyme at 60 °C, but they did not s how any increase incatalytic eciency ( kcat/Km). ForD-glucose, ... wild-type enzyme. Furth ermore, themutant enzymes exhibited up to 255 times higher inhibi-tion constants (Ki) for xylitol than the wild-type, indicat-ing t hat they are less in hibited by xylitol. ... thermalstability of the mutated enzymes was poorer than that ofthewild-typeenzyme.Theresultsarediscussedintermsofincreased molecular ¯exibility of the mutant enzymes atlow temperatures.Keywords: xylose...

Báo cáo Y học: Structural analysis of the lipopolysaccharide from nontypeable Haemophilus inﬂuenzae strain 1003 potx

... etates by gasliquid chromatography. Anal. Chem. 37, 1 602–1604.25. Prehm, P. (1980) Methylation o f carbohydrates by methyl tri-ﬂuoromethanesulfonat e in trimethyl phos phate. Carbohydr. Res.78, ... acetone and ﬁnallylyophilized from water, giving a y ield of 5 mg.Mild acid hydrolysis of LPS. Reduced core oligosac charide(OS) material was obtained after mild acid hydrolysis ofLPS ( 50 ... previouslydescribed [ 24]. Methylation analysis was performed asdescribed earlier [ 19]. Methylation ana lysis was a lso per-formed using methyl triﬂuoromethanesulphonate and 2 ,6-di-tert-butylpyridine...

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