... TKI:• Vatalanib• SamaxinibIIIPreclinicalFGFR TKI:• Brivanib• Ki23057IIPreclinicalIGF-R antibody:• CP-751,871IGF-R TKI:• OSI 906I - IIIHGF/Met-R antibody:• AMG 102HGF/Met-R TKI:• ... 201032TrastuzumabHER2/neu and TrastuzumabHER2/neu (c-erbB-2) is a transmembrane tyrosine kinase (TK) receptor, member of the human epidermal growth factor-receptor (HER) family (HER1, 2, 3 and 4). HER2 function and ... alternatives for patients who are not candidates for ECF. DCF may be recommended as an option in selected very fit patients.Tegafur (S-1), a 5FU prodrug, is standard therapy for metastatic GC in Japan;...