Color Atlas of Pharmacology (Part 14): Drugs used in Hyperlipoproteinemias

... decreased or are even increased. High dietary intake may correlate with a reduced incidence of coronary heart disease. 156 Drugs used in Hyperlipoproteinemias Lüllmann, Color Atlas of Pharmacology © ... conditions of license. Drugs used in Hyperlipoproteinemias 157 Low systemic availability Fluvastatin A. Accumulation and effect of HMG-CoA reductase inhibitors i...

Ngày tải lên: 18/10/2013, 00:15

... augmenting the activity of intraspinal inhibitory interneurons. They are used in the treat- ment of painful muscle spasms, e.g., in spinal disorders. Benzodiazepines en- hance the effectiveness of ... conditions of license. Drugs Acting on Motor Systems 189 A. Antiparkinsonian drugs Selegiline Inhibition of dopamine degradation by MAO-B in CNS Normal state Dopamine Acety...

Ngày tải lên: 24/10/2013, 19:15

... N-acetylcysteine, is given intravenously within 6–8 h after inges- tion of an excessive dose of acetamino- phen. Whether chronic regular intake of acetaminophen leads to impaired renal function remains ... anesthetics) ¼ suppression of transmission of noci- ceptive impulses in the spinal me- dulla (opioids) ¼ inhibition of pain perception (opi- oids, general anesthetics) ¼ alter...

Ngày tải lên: 24/10/2013, 19:15

... (intubation). Administra- tion of the volatile anesthetic must then be titrated in such a manner as to coun- terbalance the waning effect of the in- jectable agent. Increasing use is now being ... made of injectable, instead of inhalational, an- esthetics during prolonged combined anesthesia (total intravenous anesthe- sia—TIVA). “TIVA” has become feasible thanks to the introducti...

Ngày tải lên: 29/10/2013, 02:15

... gen- tamicin, tobramycin, amikacin, netilmi- cin, sisomycin). In addition, local inlays of a gentamicin-releasing carrier can be used in infections of bone or soft tissues. Aminoglycosides gain access ... synthesis 5. RNA DNA Incorrect: R: - I Idoxuridine - CF 3 Trifluridine - C 2 H 2 Edoxudine Insertion into DNA instead of thymidine Correct: Thymidine Thymine Desoxyribose Incor...

Ngày tải lên: 08/11/2013, 02:15

... Metabolism of morphine Nasal mucosa, e.g., heroin sniffing Intravenous application "Mainlining" Oral application Bronchial mucosa e.g., opium smoking Met-Enkephalin Morphine Fentanyl Heroin Opioid Morphine N N CH 2 CH 2 C O CH 2 CH 3 Tyr ... sug- gesting a binding site in apolar regions of the channel protein or the surround- ing lipid membrane. Mechanism-specific adverse ef-...

Ngày tải lên: 29/10/2013, 02:15

... of GABA, binding to the receptors will, therefore, be increased, resulting in an augmented response. Excitability of the neurons is diminished. Therapeutic indications for benzo- diazepines include ... disorder (i.e., distracted, incoherent, illogical thinking; impoverished intellectual content; blockage of ideation; abrupt breaking of a train of thought: claims of being subject...

Ngày tải lên: 08/11/2013, 02:15

... curves A. Insulin production S - S S - S Ala Thr30 Porcine insulin Human insulinInsulin B-chain A-chain Production: DNA E. coli Hours after injection 6 12 18 24 Intermediate Slow Insulin mixtures Insulin ... 24 Intermediate Slow Insulin mixtures Insulin suspension = protamine zinc insulin Insulin solution = regular insulin Insulin concentration in blood Rapid Lüllmann, Color Atlas of...

Ngày tải lên: 08/11/2013, 02:15

... by mechlor- ethamine Insertion of daunorubicin, doxorubicin, bleomycin, actinomycin D, etc. Streptomyces bacteria Inhibition of nucleotide synthesis Purines Thymine Nucleotide Tetrahydro- folate Dihydrofolate Reductase Folic ... synthesis Purines Thymine Nucleotide Tetrahydro- folate Dihydrofolate Reductase Folic acid Inhibition by Purine antimetabolite Insertion of incorrect building b...

Ngày tải lên: 15/12/2013, 13:15

... adverse effects of colchicine are abdominal pain, vomiting, and diarrhea, probably due to inhibition of mitoses in the rapidly di- viding gastrointestinal epithelial cells. Colchicine is usually ... mechanisms of action, inhibition of macrophage activ- ity and inhibition of release or activity of lysosomal enzymes are being dis- cussed. Included in this category are: sulfasala...

Ngày tải lên: 15/12/2013, 13:15