alternative splicing

... CHUYÊN ĐỀ SINH HỌC PHÂN TỬ EUKARYOTE 1 5- ĐIỀU HÒA SPLICING 5- ĐIỀU HÒA SPLICING 10 Ức chế splicing Ức chế splicing Tăng cường splicing Tăng cường splicing Trans-acting protein (repressor & activator) Cis-acting ... enhancer) 11 Ảnh hưởng của tốc độ kéo dài phiên mã đến sự altenative splicing Ảnh hưởng của tốc độ kéo dài phiên mã đến sự altenative splicing 12 Calcitonin C...

Ngày tải lên: 04/10/2013, 13:53

... B, Ligeti E, Demaurex N & Krause K-H (2000) A mammalian H + channel generated through alternative splicing of the NADPH oxidase homolog NOH-1. Science 287, 138–142. 13 Geiszt M, Lekstrom K, ... 2006 The Authors Journal compilation ª 2006 FEBS 3677 Expression and function of Noxo1c, an alternative splicing form of the NADPH oxidase organizer 1 Ryu Takeya 1,2 , Masahiko Taura 1 , To...

Ngày tải lên: 19/02/2014, 06:20

... the transcription initiation sites and the promoter assay revealed that not only alternative splicing but also alternative promoter con- tributed to the production of KLK11 mRNA iso- forms. Exon ... biomarkers for several types of cancer, including breast, ovarian, and prostate cancer [4]. Alternative splicing is prevalent in the Keywords hippocampus; oligo cap RACE; prostate; serin...

Ngày tải lên: 19/02/2014, 06:20

... the study of novel splicing regulatory mechanisms. There is substantial precedence for identifying novel splicing regulatory sequences and splicing factors by molecular analysis of splicing aberrations ... in the alternative splicing (AS) isoforms (that become substrates of both positive and negative natural selection). Two main categories of translationally silent varia- tions ca...

Ngày tải lên: 06/03/2014, 09:22

... Z, Toiber D, Thanaraj TA & Soreq H (2005) Function of alternative splicing. Gene 344, 1–20. 18 Xing Y & Lee C (2006) Alternative splicing and RNA selection pressure–evolutionary consequences ... 499–509. 19 Blencowe BJ (2006) Alternative splicing: new insights from global analyses. Cell 126, 37–47. 20 Tarrio R, Ayala FJ & Rodriguez-Trelles F (2008) Alternative splicin...

Ngày tải lên: 06/03/2014, 09:22

... switch-like alternative splicing events within highly expressed genes (e.g. TPM1) have been used for many years as model systems of regulated alternative splicing. Interestingly, although in many cases alternative splicing ... tissue-specific alternative splicing by motif enrichment analysis. In some cases, the motifs associ- ated with tissue-specific alternative splicing hi...

Ngày tải lên: 06/03/2014, 09:22

... 5–11. HIV-1 alternative splicing regulation J. Tazi et al. 876 FEBS Journal 277 (2010) 867–876 Journal compilation ª 2010 FEBS. No claim to original French government works MINIREVIEW Alternative splicing: ... unexplored strategies for HIV therapy. This review will focus on alternative splicing, a key event for HIV replication. HIV-1 alternative splicing mechanism The HIV-1 DNA...

Ngày tải lên: 06/03/2014, 09:22

... Two different E2F6 proteins generated by alternative splicing and internal translation initiation Tillman Dahme 1 , Jason Wood 1 , David M. Livingston 1 and ... two different mRNAs, E2F6 and E2F6b. The E2F6b mRNA contains an additional exon that is inserted by alternative splicing. This exon contains an in-frame stop-codon and an in-frame translation initiation ... isoforms under differe...

Ngày tải lên: 08/03/2014, 09:20

... protein synthesis and RNA splicing, so one might expect dif- ferences in pseudoexons with regard to several fac- tors, including the distribution of splice consensus sequences, splicing enhancers, splicing silencers ... abundance of exon splicing silencer regulatory elements within introns [1], it is not possible to formulate general rules for pseudoexon repression without remembering...

Ngày tải lên: 16/03/2014, 04:20

... al. Alternative splicing of glycine decarboxylase H-protein FEBS Journal 276 (2009) 6985–6991 ª 2009 The Authors Journal compilation ª 2009 FEBS 6989 References 1 Reddy ASN (2007) Alternative splicing ... produce multiple transcripts, but the precise function of most of the alternatively encoded proteins is not known. Alternative splicing has been reported for the H-protein subuni...

Ngày tải lên: 23/03/2014, 04:20