Báo cáo y học: "BRCA1 May Modulate Neuronal Cell Cycle Re-Entry in Alzheimer Disease"

Báo cáo y học: "BRCA1 May Modulate Neuronal Cell Cycle Re-Entry in Alzheimer Disease"

Báo cáo y học: "BRCA1 May Modulate Neuronal Cell Cycle Re-Entry in Alzheimer Disease"

... profile of many cell cycle markers, re-flecting a re-entry into the cell cycle by affected neurons. However, while such a cell cycle re-entry phenotype is an early and consistent feature of Alzheimer ... neurofibrillary tangles, BRCA1 was absent, yet BRCA1 was present in all cases of Alzheimer disease. These findings not only further define the cell cycle reentry p...

Ngày tải lên: 26/10/2012, 10:04

6 441 0
Tài liệu Báo cáo Y học: Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor pot

Tài liệu Báo cáo Y học: Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor pot

... 1–346) was linked via a single glycine residue to the N-terminus of human CNTF (amino acids 1–186). Recombinant Hyper-CNTF protein was expressed in COS-7 cells. Hyper-CNTF efficiently induced dose- dependent ... signal transducing b subunits thereby initiating cytoplasmic signaling. Cells that only express signal transducing but no ligand binding subunits for these cytokines are refractory to...

Ngày tải lên: 22/02/2014, 07:20

9 442 0
Báo cáo Y học: Amino acids 3–13 and amino acids in and flanking the 23FxxLF27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor pdf

Báo cáo Y học: Amino acids 3–13 and amino acids in and flanking the 23FxxLF27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor pdf

... and Western blot analysis Yeast protein extracts were obtained by direct lysis of yeast cells in 2 · SDS gel-loading buffer by a freeze/thawing cycle and boiling, according to Sambrook and Russell ... GalAD-ARpeptide fusion proteins in the yeast protein interaction system. (B) Interaction of GalAD-ARpeptides with AR.LBD in the presence of 1 l M DHT in the yeast protein interaction s...

Ngày tải lên: 17/03/2014, 10:20

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Báo cáo y học: "Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections"

Báo cáo y học: "Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections"

... 14distress syndrome within 30 days following inclusion.The secondary endpoint was overall survival within 30days following study inclusion. Outcomes were assessedduring hospital stay at days 3, 5, ... family ofnatriuretic peptides regulates a variety of physiologicalparameters [51]. In septic states, ANP levels may mirrorboth, the inflammatory cytokine response correlatedwith the severity...

Ngày tải lên: 25/10/2012, 10:02

14 498 0
Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"

Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"

... disclosure and analysis.Many academic centers are increasingly recognizing engage-ment in quality improvement as a distinct career pathway[15]. Involving such physicians in METs will likely facilitate ... pathway. Involving such physicians in medicalemergency teams will likely facilitate the dual roles of these as aclinical outreach arm of the intensive care unit and in identifyingpro...

Ngày tải lên: 25/10/2012, 10:06

2 428 0
Báo cáo y học: "Trace Elements, Heavy Metals and Vitamin Levels in Patients with Coronary Artery Diseas"

Báo cáo y học: "Trace Elements, Heavy Metals and Vitamin Levels in Patients with Coronary Artery Diseas"

... Turkey 4. Yuzuncu Yil University Faculty of Science, Department of Chemistry, Van, Turkey 5. Yuzuncu Yil University, Faculty of Medicine, Department of Cardiology, Van, Turkey  Corresponding ... concentrations may be increased in patients with CAD. Key words: coronary artery disease; trace element; heavy metal; vitamin INTRODUCTION Coronary artery disease (CAD) is a leading cause of morb...

Ngày tải lên: 25/10/2012, 10:51

5 527 0
Báo cáo y học: "Aplasia and Agenesis of the Frontal Sinus in Turkish Individuals: A Retrospective Study Using Dental Volumetric Tomograph"

Báo cáo y học: "Aplasia and Agenesis of the Frontal Sinus in Turkish Individuals: A Retrospective Study Using Dental Volumetric Tomograph"

... drainage system of the frontal sinus depends on its embryologic development [2,13]. The drainage usually occurs directly into the frontal recess [14] or into the frontal recess by way ... Tomogra-phy Findings in Chronic Rhinosinusitis Patients with and without Allergy. Asian Pac J Allergy Immunol. 2006;24:123-7. 7. Schaeffer J. The Embryology, Development and Anatomy of the ... frontal sinu...

Ngày tải lên: 25/10/2012, 11:04

5 578 0
Báo cáo y học: "Refractive Status and Prevalence of Refractive Errors in Suburban School-age Children"

Báo cáo y học: "Refractive Status and Prevalence of Refractive Errors in Suburban School-age Children"

... of China  Corresponding author: Dr Zheng-Qin Yin, Southwest Hospital, Southwest Eye Hospital, Third Military Medical Univer-sity, Gaotanyan 30, Shapingba District, Chongqing 400038, China; ... aged 6-15 years in Yongchuan, a socio-economically repre-sentative area in Western China. We carried out a door-to-door survey and actual eye examinations, including visual acuity measurements, ......

Ngày tải lên: 25/10/2012, 11:40

12 552 0
Báo cáo y học: " Evaluation of Lumbar Facet Joint Nerve Blocks in Managing Chronic Low Back Pain: A Randomized, Double-Blind, Controlled Trial with a 2-Year Follow-U"

Báo cáo y học: " Evaluation of Lumbar Facet Joint Nerve Blocks in Managing Chronic Low Back Pain: A Randomized, Double-Blind, Controlled Trial with a 2-Year Follow-U"

... stimulating the fa-cet joint capsule. Surprisingly, they53 also showed that the introduction of physiologic saline into the zyga-pophysial joint reduced the stimulation pathway from the intervertebral ... and validity of radiofrequency neurotomy for chronic lumbar zygapophysial joint pain. Spine (Phila Pa 1976). 2000; 25: 1270-7. 32. Merskey H, Bogduk N. Lumbar zygapophysial joint pain. In:...

Ngày tải lên: 26/10/2012, 09:07

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Báo cáo y học: "NITRIC OXIDE (NO), CITRULLINE – NO CYCLE ENZYMES, GLUTAMINE SYNTHETASE AND OXIDATIVE STRESS IN ANOXIA (HYPOBARIC HYPOXIA) AND REPERFUSION IN RAT BRAIN"

Báo cáo y học: "NITRIC OXIDE (NO), CITRULLINE – NO CYCLE ENZYMES, GLUTAMINE SYNTHETASE AND OXIDATIVE STRESS IN ANOXIA (HYPOBARIC HYPOXIA) AND REPERFUSION IN RAT BRAIN"

... activity of nitric oxide synthase. The increased activities of argininosuccinate synthetase and argininosuccinate lyase suggest the increased and effective recycling of citrulline to arginine in ... involvement in pathophysiol-ogy of hypobaric hypoxia in brain (42-43). In this study the increased activity of NOS in anoxia may represent predominantly the nNOS form. In inflam-mato...

Ngày tải lên: 26/10/2012, 09:07

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