... determine how thyroid hormones interact withxCTBP/xALDH1, resulting in the decrease in the formation of retinoic acid from retinal, kinetics of the inhibition of xCTBP/xALDH1 by T3was examined by ... later confirmed by examining boththe 3,3¢,5-triiodo-L-thyronine (T3) binding and the ALDHactivities of the recombinant xALDH1 [10]. The concen-trations of the 59-kDa xCTBP, investigated by photoaffin-ity-labeling ... T3,3,3¢,5-triiodo-L-thyronine; T4,L-thyroxine; Triac, 3,3¢,5-triiodo-L-thyroacetic acid; MBC, maximumbinding capacity; IC50, the concentration of a chemical necessary toinhibit an activity by 50%.Enzymes:...