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Báo cáo y học: "Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistyr"

Báo cáo y học:

Báo cáo y học: "Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistyr"

... 1. Synthesis of the PNA building block backbone In the next step, the synthesis of the PNA back-bone monomer using the fluorenylmethoxycarbonyl (Fmoc) protection occurred as described by Atherton ... monomer functionalized with the Reppe anhydride called RE -PNA 11 was then ready for use in the solide phase PNA synthesis. The instructions for synthesis are documented in the footnote.2 All steps of ... Synthesis of the Fmoc-C2-glycine-tert-butyl ester The synthesis of the peptide nucleic acid back-bone requires the introduction of protecting groups as shown in the Fmoc-C2-glycine-tert-butyl...
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Báo cáo Y học: Characterization of the exopolysaccharide produced by Streptococcus thermophilus 8S containing an open chain nononic acid doc

Báo cáo Y học: Characterization of the exopolysaccharide produced by Streptococcus thermophilus 8S containing an open chain nononic acid doc

... influencing their physical properties[27], the presence of Sug in the backbone of the EPSproduced by S. thermophilus 8S will most likely haveconsequences for the physical properties of the EPS.Furthermore, ... hexa-methyldisilazane-trimethylchlorosilane-pyridine), and the resulting mixtures of methyl glycosides were analyzed onGLC [14,15]. The absolute configurations of the monosac-charides were determined by GLC analysis of the trimeth-ylsilylated ... constituent of the repeating unit of an EPS produced by a Gram-positive lacticacid bacterium.Due to the novel composition of the EPS produced by S. thermophilus 8S, the genetics and biochemistry of the EPS...
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Báo cáo y học:

Báo cáo y học: "Use of the measure your medical outcome profile (MYMOP2) and W-BQ12 (Well-Being) outcomes measures to evaluate chiropractic treatment: an observational study"

... asignificant step forwards to assess the utility of thesequestionnaires in another practice setting.Therefore the aim of this observational study was toassess the utility of the MYMOP2 and W-BQ12 ... and forms utilised for the study.Patients were invited to participate in the study if theywere: over the age of 18 years; had no treatment fromany health professional for their complaint in the ... inserted the previously cho-sen symptoms and activity onto the follow-up formprior to this being given to the patient to score. There-fore, the patient was aware of the symptoms they hadpreviously nominated,...
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Báo cáo y học:

Báo cáo y học: "Impact of the Kenya post-election crisis on clinic attendance and medication adherence for HIV-infected children in western Kenya"

... faced during the crisisperiod:▪ There was one boy who was being taken care of by theuncle. They stay in Langas. Langas was, let me say, it wasthe heat of the violence there. This boy is on second ... disconfirming the codes and the subse-quent themes. Data triangulation was used by comparingthe information reported in the interview dialogue withclinic information recorded by the AMPATH care systemabout ... and supply short-ages.[24] The computerized medical record systemremained functional throughout the duration of the crisisthough the entry of data from paper encounter forms wasdelayed by several...
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Báo cáo y học:

Báo cáo y học: "Evaluation of the Prevalence of Concomitant Idiopathic Cyclic Edema and Cellulit"

... in the morning which im-proves later in the day. Some patients reported facial edema early in the morning and swelling of the legs at the end of the day. Participants were asked to weigh themselves ... to less than 300 grams. The frequency of edema was considered in the statistical analysis. The study was approved by the Research Ethics Committee of the Medical School in ... daily. Statistical analysis con-sidered the frequency of edema. Of the 82 women evaluated with ages between 18 and 58 years old (mean of 34.9 years) 41 (50.0%) were diagnosed with idiopathic cyclic...
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Báo cáo y học:

Báo cáo y học: "Enhancement of the Click Chemistry for the Inverse Diels Alder Technology by Functionalization of Amide-Based Monomers"

... components by use of the inverse Diels Alder technology. The high chemical stability and the ease of synthesis qualify these polyamide building blocks as favourites for intracellular ... compounds by coupling to the glycine’s N-terminus, as originally described by Nielsen in the protocols for the synthesis of the peptide nucleic acid (PNA) backbone [29, 30]. We synthesized ... tri-ethylsilane. 5. Solid phase synthesis of the Reppe Anhy-dride polyamide pentamer I. To demonstrate the high efficiency of the DARinv-based Click -chemistry, we synthesized...
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 Báo cáo y học:

Báo cáo y học: " Efficacy of the Valsalva Maneuver on Needle Projection Pain and Hemodynamic Responses During Spinal Puncture"

... balloon group compared with the other 2 groups (p<0.05).These findings were correlated with our study. In another study by Agrawal et al, the efficacy of the Valsalva maneuver on ... group for the results to be statistically significant at a power of 95% with a level of confidence of 5%. Data were analyzed by SPSS version 11.5(SPSS Inc., Chi-cago, IL). Normality of ... exploring the effect of the Valsalva maneuver on pain.6-10 In a study by Agrawal et al, Valsalva maneuver performed before venous canulation could decrease the incidence and severity of pain...
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Báo cáo y học:

Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"

... group was similar as the frequency of 0.21 reported by Chen et al. in their study for chd patients derived from the lipoprotein coronary atherosclerosis study. Conversely, Skogsberg et al. found ... Results The frequency of the C-allele was 0.24 and the genotypes were distributed according to the Hardy Weinberg Equilibrium. Overall the C allele frequency was higher in patients with coronary heart ... detected by silver staining on polyacrylamid gel. Statistical Analysis Allele frequencies were determined by gene counting and compared using the א² test. The data was analysed using SPSS 12.0 software....
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Báo cáo y học:

Báo cáo y học: "Study of the early steps of the Hepatitis B Virus life cycle"

... studies of the uptake of DHBV by duck primary hepatocytes (PDH). However, the entry route for DHBV is still unclear. As we have mentioned before, there are two entryways that the viruses use for their ... suggests that DHBV may use the endocytosis way for its entry [66]. This hypothesis was supported by the observation of the conformation change of the large surface protein of DHBV at low pH condition ... inhibited by recombinant HBs but not by the recombinant LHBs. The binding of SHBs with human hepatocytes was further supported by the observation from Bruin et al [39]. They have found that the particles...
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Tài liệu Báo cáo Y học: Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species pptx

Tài liệu Báo cáo Y học: Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species pptx

... efficiently oxidized by the enzymes of the respiratorychain, specifically designed for the NADH oxidation.However, the current study shows that superoxide is cata-lytically produced by the complex-bound ... 1e–oxidation of the carbanion in the E1 active site(a product of reaction 1) by highly electrophilic thiyl radical of the dihydrolipoyl residue of E2 had to be expected. The reaction was confirmed by anaerobic ... half of the lipoyl residues of the E2 oligomer may be removed withoutsignificant change in the overall activity [40–42]. If the residues function only as catalytic intermediates, the reason for their...
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