Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"
... located in the portion of body or tail of the pancreas. For tumors of SPT located in the neck and body of the pancreas, resection of the mid-portion of the pancreas and the mass with preserving the ... Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less? Hong Chang1, Yi Gong2, Jian Xu1, Zhong...
Ngày tải lên: 25/10/2012, 11:40
... respectively) to the proteins enco- ded by ORFs in the clusters responsible for synthesizing the SPAs in other serotypes of A. actinomycetemcomitans. The biosynthetic pathway for GDP-6-deoxy- D -talose, Fig. ... and the stereoselectivity of the reduction deter- mines the direction of synthesis of these two 6-deoxyhex- oses. However, neither the gene encoding the...
Ngày tải lên: 17/03/2014, 10:20
... namely that they contain a hydrogen-bond donor in wing2. This property is of general importance for the efficacy of the inhibitor. Substitution of the hydrogen-donating amide group for a methylene ... plane of the thiourea moiety and the Ca of G190. Hence, the undefined orientation of the N103 amide Od1 and Nd2 atoms may r eflect the repulsive forces exerted on t...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo khoa học: A strategy for the generation of specific human antibodies by directed evolution and phage display An example of a single-chain antibody fragment that neutralizes a major component of scorpion venom docx
... specific for Cn2 toxin (Fig. 2), they were not able to neutralize it. Analysis of the affinity constants showed values in the range 10 )7 m (Table 1), which are typical affinity values for the primary ... j chains and each HuVkFOR with a mixture of HuJkBACK for k chains. A GeneAmp PCR thermocycler (Perkin-Elmer 9600, Norwalk, CT, USA) was used for PCR. The condi- tions for...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo Y học: A model for recognition of polychlorinated dibenzo-p-dioxins by the aryl hydrocarbon receptor docx
... [16]. For both FixL and PYP, structures are known for the inactive and active signaling states. In the case of PYP, conformational changes occur in the neighborhood of the p-hydroxycinnamoyl cromophore ... model of the ligand binding domain (LBD) of the mouse aryl hydrocarbon receptor (mAhR). The model allowed us to putatively i dentify the residues responsible fo...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo y học: "Clinical review: Treatment of new-onset atrial fibrillation in medical intensive care patients – a clinical framework"
... the start of AF [44].Conclusion on morbidityIn all patient categories, AF is associated with increasedmorbidity. This is reflected by the number of reportedsymptoms and by the days spent in the ... that the cause of AFis multifactorial. There are more or less permanent changes inmorphology and more or less temporary changes inhaemodynamic balance, electrolyte balance, neur...
Ngày tải lên: 25/10/2012, 10:35
Báo cáo y học: "Clinical review: Medication errors in critical care"
... Spontaneous reporting of medicationerrors may under-report events [11,22]. Review of themedical records is considered by many experts the bench-mark for estimating the extent of errors and adverse ... medicationerrors?Medication errors are an important cause of patient morbidityand mortality [9]. Although only 10% of medication errorsresult in an ADE, these errors have profoun...
Ngày tải lên: 25/10/2012, 10:35
Báo cáo y học: "Parvovirus B19 Genotype Specific Amino Acid Substitution in NS1 Reduces the Protein’s Cytotoxicity in Culture"
... apoptosis as the underlying mechanism for the cytotoxicity observed in the setting of transient B19 NS1 expression (34). We therefore examined whether the reduced cell loss ob-served in the PathI ... room temperature in the dark and immediately ana-lyzed by flow cytometry. The percentage of cells ex-pressing the EGFP marker, as well as the distribution of signal inte...
Ngày tải lên: 26/10/2012, 09:32
Báo cáo y học: "Enhanced surveillance for childhood hepatitis B virus infection in Canada, 1999-2003"
... screening for HBsAg in non-Canadian-born children may provide the means for detecting most HBsAg carriers with heretofore undiagnosed HB. Screening in these children for HBV is important for identifying ... jurisdiction, either automatically reported or were contacted regularly for newly identified HB cases, laboratory test results, and other related information. A standardized...
Ngày tải lên: 02/11/2012, 11:08
Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
... responsible for the thermolability of MTHFR. Actually, the frequency of the mutated allele was quite high, depending on the ethnic group analyzed [18-21]. Some authors suggested that the homozygosity for ... persons, and the results were concordant for all masked cases. Statistical analysis: The distributions of plasma tHcy concentrations were positively skewed; ther...
Ngày tải lên: 03/11/2012, 09:49