Báo cáo y học: "Pathogenic Mechanisms Shared between Psoriasis and Cardiovascular Diseas"

Báo cáo Y học: Molecular mechanisms underlying SHP-1 gene expression potx

Báo cáo Y học: Molecular mechanisms underlying SHP-1 gene expression potx

... shifted bands (X and Y) . As bands X and Y were only partially inhibited by 500-fold excess of unlabelled wild-type oligo- nucleotide, we propose that the proteins involved in these complexes have very ... tyrosine kinases and phosphatases are the key players in the regulation of protein tyrosine phosphorylation. Among the known protein tyrosine phosphatases, SHP-1 and SHP-2 are di...

Ngày tải lên: 08/03/2014, 23:20

8 418 0
Báo cáo Y học: Ligand-induced heterodimerization between the ligand binding domains of the Drosophila ecdysteroid receptor and ultraspiracle docx

Báo cáo Y học: Ligand-induced heterodimerization between the ligand binding domains of the Drosophila ecdysteroid receptor and ultraspiracle docx

... greatly enhanced upon adminis- tration of active ecdysteroids in a dose-dependent manner. This was shown in vivo by a yeast two-hybrid system and in vitro by a modified electromobility shift assay. ... expressed in yeast was functional and bound radioactively labelled ecdysteroid specifically. Ligand binding was greatly enhanced by the presence of a USP ligand binding domain. Therefore, ecd...

Ngày tải lên: 18/03/2014, 01:20

9 332 0
Báo cáo Y học: Chromatin assembly Cooperation between histone chaperones and ATP-dependent nucleosome remodeling machines docx

Báo cáo Y học: Chromatin assembly Cooperation between histone chaperones and ATP-dependent nucleosome remodeling machines docx

... many phenotypesthatare not shared with CAF-1 mutants, including growth defects, sensitivity to double- strand DNA damage, sensitivity to hydroxyurea, suppres- sor of Ty or Spt phenotype, and ... are acetylated at lysine residues 5 and 12 of H4, and lysine residue 14 of H3 (in Drosophila) prior to their assembly into chromatin, and are rapidly deacetylated after their deposition onto...

Ngày tải lên: 31/03/2014, 21:21

7 326 0
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