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Báo cáo y học: "Prevalence of Overactive Bladder, its Under-Diagnosis, and Risk Factors in a Male Urologic Veterans Population"

Báo cáo y học:

Báo cáo y học: "Prevalence of Overactive Bladder, its Under-Diagnosis, and Risk Factors in a Male Urologic Veterans Population"

... Publisher. All rights reserved Research Paper Prevalence of Overactive Bladder, its Under-Diagnosis, and Risk Factors in a Male Urologic Veterans Population Wellman W Cheung1, William Blank1, Dorota ... population is under-diagnosed and under-treated. Key words: overactive bladder, OAB, incontinence, male, urology, veterans INTRODUCTION Recent international population and non-population ... urologic male veterans popula-tion, the need for OAB screening, and risk factors for OAB. METHODS An IRB-approved self-administered question-naire on urinary symptoms was given to male pa-tients...
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Báo cáo y học:

Báo cáo y học: "Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain"

... once daily for 7 days, starting from 1 day before CCI surgery. Evaluation of tactile allodynia and thermal hyperalgesia The paw withdrawal latency (PWL) to radiant heat and paw withdrawal threshold ... Neuropathic pain is characterized by hyperalge-sia, allodynia and spontaneous pain. It often occurs as a result of injury to peripheral nerves, dorsal root ganglions (DRG), spinal cord, or brain. ... treating neuropathic pain by inhibiting TLR4. Our results demonstrated that in- trathecal siRNA-mediated suppression of TLR4 attenuated CCI-induced mechanical allodynia and thermal hyperalgesia...
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Báo cáo Y học: Complexation of ytterbium to human transferrin and its uptake by K562 cells pot

Báo cáo Y học: Complexation of ytterbium to human transferrin and its uptake by K562 cells pot

... a glycoprotein(80 kDa) present in blood plasma with a concentration of 35 lM.Itisonly30%saturatedwithironinbloodplasma and has the capacity for binding to other metal ions of therapeutic and ... occurred. Although the signals werebroadened and shifted by Yb3+due to its paramagneticcharacter, the appearance of a new signal at 2.120 p.p.m. and the splitting of signals at 2.084 and 2.045 ... decreased almostlinearly upon addition of 2, 4, 6, 8 and 10 mol equiv of citrate, and finally reached to < 10% of its original value.The very minor decrease in absorbance upon furtheraddition of...
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Báo cáo Y học: Interaction of bovine coagulation factor X and its glutamic-acid-containing fragments with phospholipid membranes A surface plasmon resonance study pdf

Báo cáo Y học: Interaction of bovine coagulation factor X and its glutamic-acid-containing fragments with phospholipid membranes A surface plasmon resonance study pdf

... of domainsother than the Gla domain on membrane binding, we havenow investigated the membrane-binding properties of coagulation factor X and Gla domain-containing frag-ments of this protein.MATERIALS ... binding of factor X and its Gla-containing fragments to membranes containing 25 mol% PtdSer in the presence of 10 mMCa2+obtained by evaluation of association and dissociation phases (I) and equilibrium ... The Ca2+titration curves of factor X and Gla–EGFNbinding indicate cooperative binding (Fig. 1). Half-maximal binding occurred at a calcium concentration of 1.5 and 1.4 mMfor factor X and...
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Báo cáo Y học: Evaluation of two biosynthetic pathways to d-aminolevulinic acid in Euglena gracilis potx

Báo cáo Y học: Evaluation of two biosynthetic pathways to d-aminolevulinic acid in Euglena gracilis potx

... Evaluation of two biosynthetic pathways to d-aminolevulinic acid in Euglena gracilisKatsumi Iida, Ippei Mimura and Masahiro KajiwaraDepartment of Medicinal Chemistry, Meiji Pharmaceutical ... University, Kiyose-shi, Tokyo, Japand-Aminolevulinic acid (ALA), which is an intermediate in the b iosynthesis o f c hlorophyll a, c an be biosynthesized viathe C5 pathway and the Shemin pathway in ... suggesting that ALA incorporated in the13C-labeled chlorophyll a was synthesized via both the C5pathway and the Shemin pathway in a ratio of between 1.5 and 1.7 to one. The methoxyl carbon of...
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Báo cáo Y học: Regulation of glypican-1, syndecan-1 and syndecan-4 mRNAs expression by follicle-stimulating hormone, cAMP increase and calcium influx during rat Sertoli cell development pptx

Báo cáo Y học: Regulation of glypican-1, syndecan-1 and syndecan-4 mRNAs expression by follicle-stimulating hormone, cAMP increase and calcium influx during rat Sertoli cell development pptx

... 5¢-AAAAATGTTGCTGCCCTG-3¢ for syndecan-4; 5¢-GAATGACTCGGAGCGTACACTG-3¢ and 5¢-CCTTTGAGCACATTTCGGCAA-3¢for glypican-1; 5¢-ACAGACTACCTCATGAAGAT-3¢ and 5¢-AGCCATGCCAAATGTCTCAT-3¢ for b-actin.The ... regulation ismainly transcriptional [8].Syndecans and glypicans bind a variety of extracellularmatrix molecules and growth factors in a heparan sulfatedependent manner [15]. Consequently, they ... hormone induces the increase of intracel-lular cyclic AMP and calcium levels.Effect of intracellular cAMP level increaseThe involvement of the cAMP pathway was evaluated usingthree approaches, all...
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Báo cáo Y học: Synthesis of phosphoenol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes pot

Báo cáo Y học: Synthesis of phosphoenol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes pot

... [36], and pyruvate kinase [6].Inhibition of pyruvate kinase. This enzyme catalyses theregeneration of ATP from ADP and PEP, in the last step of glycolysis. Due to its physiological relevance, pyruvatekinase ... PEP analogues 1c,d, 2g and 3c in thepresence of Mg2+, and were then assayed for residualcatalytic activity with their natural substrates. Inactivation of PEP carboxylase and enolase was also ... carboxylate-modified analogues, onlythose replaced by a negatively charged group inhibitedpyruvate kinase and enolase. Remarkably, the activity of PEP carboxylase was stimulated by derivatives with neutralgroups...
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Báo cáo Y học: Expression of glucose transporter-2, glucokinase and mitochondrial glycerolphosphate dehydrogenase in pancreatic islets during rat ontogenesis potx

Báo cáo Y học: Expression of glucose transporter-2, glucokinase and mitochondrial glycerolphosphate dehydrogenase in pancreatic islets during rat ontogenesis potx

... frozen at )80 °C until theinsulin assays. Insulin was measured by the radioimmun o-assay method of Herbert et al. [15], using rat insulin as a standa rd.RNA isolation and Northern-blot analysisTotal ... Ontogenesis of hexokinase I and glucokinase protein in rat pancreatic islets and liver. Western-blot analyses of glucokinase in pancreatic islets (A) and liver (B) and hexokinase I in pancreatic islets ... 14.7%found in young adult animals.Ontogenesis of GLUT-2 and glucokinase mRNA and protein in rat pancretic islets and liverAs compared with adults, in pancreatic islets of fetal and suckling rats,...
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Báo cáo Y học: Comparison of starch branching enzyme I and II from potato ppt

Báo cáo Y học: Comparison of starch branching enzyme I and II from potato ppt

... use.Determination of branching enzyme activity on amylose and amylopectin with the starch–iodine assayAmylose (type III, Sigma) and amylopectin (Sigma) frompotato were typically dissolved at 10 mg:mL21 in ... added to obtain increasing concen-trations of phosphate. Incubations were terminated at120 min and analysed by the starch –iodine assay.Incubation of linear dextrins with branching enzyme forgel-permeation ... in the iodine-activity assaywith commercially available amylose and amylopectin assubstrates. The delta absorbance at 655 nm for the amylosesubstrate and 520 nm for the amylopectin substrate,...
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Tài liệu Báo cáo khoa học: Roles of the human Rad51 L1 and L2 loops in DNA binding doc

Tài liệu Báo cáo khoa học: Roles of the human Rad51 L1 and L2 loops in DNA binding doc

... loop for DNAbinding by RecA ⁄ Rad51 family proteins was observedby mutational and photocrosslinking analyses of RecA[34–37] and a mutational analysis of HsDmc1 [22].The Dmc1-F23 3A mutation, which ... compilation ª 2006 FEBS 3159Roles of the human Rad51 L1 and L2 loops in DNA bindingYusuke Matsuo1, Isao Sakane2, Yoshimasa Takizawa1, Masayuki Takahashi3 and Hitoshi Kurumizaka1,21 Graduate ... Because aromatic residues are involved in the ssDNA binding by bacterial single strandedDNA-binding protein (SSB) and human replicationprotein A (RPA) [23,24], we performed mutationalanalyses...
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