... its exceptional ligand bindingcapacity, the most strongly bound compounds beinghydrophobic organic anions of medium size, long-chainfatty acids, haem and bilirubin. Smaller and lesshydrophobic ... terminal regions of sequential domains contribute to the formation of inter-domain helices linking domain I to II, and II to III,respectively. On the other hand, each domain is known toconsist ... number of events involving the holoprotein bytaking advantage of electronic absorption spectroscopy,EPR spectroscopy and 1H-NMR relaxometry [7,8,10,21,22].Here, the effect of ibuprofen and warfarin...