Báo cáo khoa học: "The clinical value of daily routine chest radiographs in a mixed medical–surgical intensive care unit is low"

... patients.IntroductionChest radiographs (CXRs) are frequently obtained in intensivecare units (ICUs) [1]. They can be obtained routinely, on a dailybasis (so-called &apos ;daily routine CXRs'); such radiographs ... (6.4%)Predefined major abnormalities are summarized in Table 1. aAbsolute number of chest radiographs (% of all daily routine chest radiographs) . bAbsolute number of patients (% of all patients with daily ... Financial impact of elimination ofroutine chest radiographs in a pediatric intensive care unit. Crit Care Med 1999, 27:1588-1593.11. Krivopal M, Shlobin OA, Schwartzstein RM: Utility of daily routineportable...

Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... E2Fs cooperate with NF-Y proteins binding toCCAAT-boxes and with Myb proteins associating with a distal Myb site in activating the Cdc2 promoter.Binding of the activating E2Fs during the cell ... formation and stabilization at the spindle poleduring chromosome segregationAURKB aurora kinase B Protein kinase, key regulator of cytokinesis, mediates attachement of the mitoticspindle to ... contrast, cyclin B1 and cyclin B2are central to the regulation of progress through thecell cycle (Fig. 1). Cyclins B1 and B2 appear in S phaseand accumulate in G2and mitosis before disappearingat...

Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

... dominant polymorph a- chitin (antiparallel packing of the chitin chains);b-chitin (parallel packing of the chitin chains); and theminor polymorph c-chitin (mixture of parallel andantiparallel ... complemen-tary strategies to gain access to and degrade individualpolymer chains. First, the chains are degraded by bothendochitinases, that attack the chitin chain randomly,and exochitinases, that attack ... a rapid phase, regardless of the presence of LlCBP3 3A. In the presence of LlCBP3 3A, the fastinitial phase was maintained longer than in the absence of LlCBP3 3A, indicating that LlCBP3 3A acts...

Báo cáo khoa học: The hyperﬂuidization of mammalian cell membranes acts as a signal to initiate the heat shock protein response pptx

... noteworthy uniform increase in DYm. The quantiﬁcation of DYm in arbitrary units in response to gradually increasing heat and increasingconcentrations of the membrane ﬂuidizers is displayedon Fig. ... activation of kinases such as Akt has been shown to increaseHSF1 activity. Enhanced Ras maturation by heat stresswas associated with a heightened activation of extra-cellular signal-regulated ... factor receptor activation to the signalingcascade, it is likely that any alteration in surface mem-brane ﬂuidity could greatly in uence ERK activation. In fact, ERK activation in aged hepatocytes...

Báo cáo khoa học: The functional genomics of guanylyl cyclase⁄natriuretic peptide receptor-A: Perspectives and paradigms potx

... that seen in the GC receptor family, containing at least four dis-tinct regions: an extracellular ligand-binding domain, a single transmembrane-spanning region, an intracellularprotein kinase-like ... [5,11,12]. Gaining insights into the intrica-cies of ANP–NPRA signaling is of pivotal importancefor understanding both receptor biology and the diseasestate arising from abnormal hormone–receptor interac-tions. ... efﬁcientsignaling of the GDAY motif in the internalization of GC -A ⁄ NPRA. The mutation of Asp921 to alanine didnot have a major effect on internalization, but signiﬁ-cantly attenuated the recycling of...

Báo cáo khoa học: The molecular basis of heme oxygenase deﬁciency in the pcd1 mutant of pea pot

... products of total RNA isola-ted from P. sativum cv. Solara using degenerate primersPS1.FOR 5¢-GAG GAN ATG AGN TTN GTN GCNATG AGA-3¢ and PS1.REV 5¢-CCA CCA GCA NTATGN GNA AAG TAG AT-3¢. Ampliﬁcation ... polyclonal anti-body raised to AtHO1 [10] with a goat antirabbit IgG-alkaline phosphatase conjugate as the secondary antibody(Sigma-Aldrich Company Ltd).Expression of recombinant PsHO1The coding ... (1993) Comparative protein mod-eling by satisfaction of spatial restraints. J Mol Biol234, 779–815.Supplementary materialThe following supplementary material is availableonline:Table S1....

Báo cáo khoa học: "METONYMY: REASSESSMENT, SURVEY OF ACCEPTABILITY, AND ITS TREATMENT IN A MACHINE TRANSLATION SYSTEM S" ppt

... article we outline a basic approach to treating metonymy properly in a multil- ingual machine translation system. This is the first attempt at treating metonymy in an machine translation environment. ... METONYMY: REASSESSMENT, SURVEY OF ACCEPTABILITY, AND ITS TREATMENT IN A MACHINE TRANSLATION SYSTEM Shin-ichiro Kamei* & Takahiro Wakao Computing Research Laboratory New Mexico State University ... sign said fishing was prohibited here." AN APPROACH TO TRANSLATING METONYMY An important point to realize is that actual computational treatment of metonymic expressions is determined...

Tài liệu Báo cáo khoa học: The capsid protein of human immunodeﬁciency virus: intersubunit interactions during virus assembly doc

... foldeddomains of Gag are then able to reassemble as inde-pendent proteins. The matrix protein (MA; the GagN-terminal domain), remains associated with the viralmembrane, forming a discontinuous inner ... as a part of Gag, as anunassembled protein, and as an independent proteinforming the mature capsid. Remarkably, the CA poly-peptide appears to have evolved an extraordinary con-formational ... N-terminal domain, MA, associated with the innerlayer of the viral membrane, and the remainingdomains forming the innermost protein layers accor-ding to their positions in Gag: MA, CA-NTD,CA-CTD,...

Tài liệu Báo cáo khoa học: The capsid protein of human immunodeﬁciency virus: designing inhibitors of capsid assembly ppt

... devel-opment of new antiviral drugs that are able to interact with CA and ⁄ or itsdomains, hampering HIV-1 assembly and infection.AbbreviationsCA, capsid protein of HIV-1 (p24); CAC1, a CTD-binding ... use of drugs such as Bevirimat(Panacos Pharmaceuticals, Watertown, MA, USA)(although it is in Phase II trials) is not discussedbecause its mechanism of action is not based on inhibi-tion of ... collaboration over allthese years. Dr Anjali P. Mascarenhas and ProfessorKarin Musier-Forsyth are thanked for critically read-ing and correcting an early version of the manuscript.Marı´a...

Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

... phosphate in lysis buffer) was added per well[29]. Changes in absorption at 405 nm were followed over30 min using an ELISA plate reader. For determination of inhibition by noggin, the AP assay was ... superfamily.Structural features of proteins in this family includethe arrangement of disulﬁde bridges in a cystine knotand the anti-parallel association of the two monomers,which are linked ... Ghayor C, Suzuki A, PalmerG & Caverzasio J (2003) Activation of p38 mitogen-activated protein kinase and c-Jun-NH2-terminal kinaseby BMP-2 and their implication in the stimulation of osteoblastic...

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