Báo cáo y học: "Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients"

... infavour of Ang-2 is present in critically ill medical patients. Ourfindings highlight the independent prognostic impact ofcirculating Ang-2 in critical illness. Ang-2 may be used as areadily available ... study is a prospective clinical investigation of theprognostic value of circulating Ang-2 as a biomarker in criti-cally ill patients. The results are that: cr...

Ngày tải lên: 25/10/2012, 10:31

... ectopically expressed cdk3 in association with either cyclin E or cyclin A by transient transfection (Fig. 2A) . Kinase assays indicated that pRb- phosphorylating activity was prominently upregulated ... and B arised by incomplete tryptic cleavage of the Ser274-containing region. In fact, phosphoamino-acid analysis of spots A and B indicated that both spots A and B contained pho...

Ngày tải lên: 24/03/2014, 04:21

... mechanism of action Mikhail A. Panteleev, Veronica I. Zarnitsina and Fazoil I. Ataullakhanov National Research Center for Hematology, Russian Academy of Medical Sciences, Moscow, Russia We have analyzed ... result of binding of TFPI to the enzyme–product Xa–VIIa–TF complex and this is the main pathway of inhibition of VIIa–TF during ongoing factor X activation. Analysis of...

Ngày tải lên: 22/02/2014, 04:20

... normal distribution, and such data were analysed statistically. Statistical analysis of the data analysis was carried out using the ANOVA test. Prevalence of alleles and genotype among cases and ... Mukawa H, Tomida T, Suzuki T, Kamiya H, Matsui H, Hayakawa T. Relation of a common methylenetetrahydrofolate reductase mutation and plasma homocysteine with intimal hyperplasia after coron...

Ngày tải lên: 03/11/2012, 09:49

... using ethyl acetate/cyclohexane (2 : 3) as a solvent, with dansylated derivatives of known polyamines serving as markers. The individual polyamines were visualized by UV illumination. RESULTS Antizyme ... ubiquitin system for its degradation. DISCUSSION Antizyme is a unique cellular regulatory protein that is both regulated by polyamines and regulates polyamine metabo- lism in a...

Ngày tải lên: 22/02/2014, 04:20

... overexpressing the wild-type DAP kinase, t he DCaM-DAP kinase m utant (a c onstitutively active kinase mutant), the K 4 2A- DAP kinase mutant (a catalytically inactive mutant displaying dominant negative features), ... a catalytically inactive DAP kinase mutant and a construct containing the death domain and C-terminal tail of DAP kinase, which act in a dominant-n egative manner,...

Ngày tải lên: 24/03/2014, 00:21

... extracellu- lar ligand-binding domain, a single transmembrane domain, an intracellular kinase homology domain (KHD) and a catalytic domain (reviewed in [1]). Soluble guanylate cyclases (sGCs) are ... composed of a and b subunits and each monomer contains a heme binding domain, a dimeri- zation domain, and a catalytic domain [1,6]. The primary structure of the catalytic domai...

Ngày tải lên: 24/03/2014, 03:21

... bleeding was controlled by #3-0 Vycryl intracorporeal suture, and the invagination of the diverticulum was performed laparoscopically. The recovery was une-ventful, and the patient was discharged ... motility [3]. In most cases, it is asymptomatic, but major complica-tions could include diverticulitis and intraluminal hemorrhage [4, 5]. Interestingly, intraperitoneal hemorrhage of ......

Ngày tải lên: 25/10/2012, 10:51

... proximally extended, leading to impaired daily activity and creating a sensation of heaviness and discomfort. There was no family history of similar disorders. A conventional approach was ... medical history of primary lower limb lymphedema diagnosis by specialists and all accepted to participate in this study when they were asked. Patient’s health status was measured us-ing ......

Ngày tải lên: 25/10/2012, 11:40