... Relocalization of RAS from the cytoplasmic to the cytoskeleton fraction could suggest an involvement of RAS during cytoskeleton rearrangement of platelets Our study shows that in platelets RAS is not sufficient ... activation of PKC, does not stimulate activation of ERK in platelets This result indicates that activation of RAS is not suffic...
Ngày tải lên: 08/03/2014, 16:20
... association with FcR c-chain Fig FcR c-chain and the cytoplasmic tail of GPVI are necessary to initiate the GPVI signalling cascade (A) K562 cells stably transfected with FcR c-chain and cotransfected ... FcR c-chain is necessary for GPVI signalling upon convulxin stimulation To investigate whether GPVI was functional, we measured tyrosine phosphorylation...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: The C-terminal region of ammodytoxins is important but not sufficient for neurotoxicity pot
... perfectly match their theoretical values, assuming formation of all seven disulfide bonds in the sPLA2 molecule Influence of the mutations on the secondary structure and overall conformation of the ... toxicity of the construct; only the enzymatic activity on PtdCho–Triton X-100 mixed micelles increased twofold The increase in enzymatic activity of the N24F chimera was...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo y học: "Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors" pps
... &RQWUROV Figure Sensitivity of HIV-1 R5 envelopes to reagents that interfere with gp120 :CD4 interactions Sensitivity of HIV-1 R5 envelopes to reagents that interfere with gp120 :CD4 interactions ... &RQWUROV Figure Sensitivity of HIV-1 R5 envelopes to reagents that interfere with gp120:CCR5 interactions Sensitivity of HIV-1 R5 envelopes...
Ngày tải lên: 13/08/2014, 06:20
Báo cáo khoa học: "Quantitative modeling of the neural representation of adjective-noun phrases to account for fMRI activation" doc
... model The adjective model assumes that the meaning of the composition is the same as the adjective: p=u The noun model assumes that the meaning of the composition is the same as the noun: p=v The ... found the modifier-head interpretation of the multiplicative model to best account for the neural activity observed in adjective-noun phrase data Table...
Ngày tải lên: 30/03/2014, 23:20
Báo cáo khoa hoc:" An expression of mixed animal model means equations to account for different and variances in the base" pps
... valid to assume that the breeding values of the base animals have the same mean and variance, and that the genetic variance of the base generation is twice that of the Mendelian variance In a ... set up the equations corresponding to an animal model with base animals treated as fixed and an additive genetic animal model with groups and relations...
Ngày tải lên: 09/08/2014, 18:21
Báo cáo y học: " Membrane diffusion- and capillary blood volume measurements are not useful as screening tools for pulmonary arterial hypertension in systemic sclerosis: a case control study" pptx
... in a decrease in capillary flow and thus a decrease in Vc This will result in a reduction in surface area available for gas exchange, and therefore in a decrease of Dm [25] Secondly, parenchymal ... capacity of the alveolar capillary membrane as percentage of predicted (Vc%/Dm%) and the pulmonary vascular resistance (PVR) and the mean pulmonary artery...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: " We still fail to account for Mendel''''s observations" pot
... initially identified by the symbol (A) were allowed to self-fertilise some proved to be 'constant form' plants because, when they were allowed to self-fertilise, they produced F3 progeny that ... again not 'constant form' plants They were like the F1 plants (their "grandparents") and like the F2 parents from which they were immediately derived When they were allowed to self-fertilise,...
Ngày tải lên: 13/08/2014, 22:22
Tài liệu In this lab, 2 ISDN routers are required. If ISDN routers are not available, review the lab to become familiar with the process. An Adtran Atlas550 ISDN emulator is used to simulate the switch/ISDN cloud. pdf
... refer to the chart at the end of the lab to correctly identify the interface identifiers to be used based on the equipment in the lab The configuration output used in this lab is produced from 1 721 ... combinations of interfaces in the device This interface chart does not include any other type of interface even though a specific router may conta...
Ngày tải lên: 21/12/2013, 19:15
Báo cáo khoa học: Intrinsic local disorder and a network of charge–charge interactions are key to actinoporin membrane disruption and cytotoxicity ppt
... hypothesize that actinoporins act in at least two stages: (a) an initial approach to and binding of the membrane; (b) oligomerization, pore formation and lysis We also hypothesize that R29 and Y111 ... replaced by a group which is also structurally planar and able to accept and donate H-bonds In this context, our data indicate that the positive surface together with a ne...
Ngày tải lên: 14/03/2014, 23:20
Báo cáo y học: " T cell receptor transgenic lymphocytes inflitrating murine tumors are not induced to express foxp3" potx
... Splenocytes (SPL), T Cell Receptor (TCR), Regulatory T cells 14 (Treg), Induced Regulatory T cells (iTreg), Tumor Infiltrating Lymphocytes (TIL), Transforming Growth Factor Beta (TGFβ) COMPETING INTERESTS ... vitro to act in concert, but not alone, with TGFβ to induce Foxp3, did not support 11 induction of iTreg in these transgenic mice These findings indirectly suppor...
Ngày tải lên: 10/08/2014, 21:23
Báo cáo khoa hoc:" Gastrointestinal complaints in runners are not due to small intestinal bacterial overgrowth" pot
... lactose intolerance N Engl J Med 1995, 333(1):1-4 doi:10.1186/1477-5751-10-8 Cite this article as: Schommer et al.: Gastrointestinal complaints in runners are not due to small intestinal bacterial ... Trinick T: Gastrointestinal disturbances in marathon runners Br J Sports Med 1988, 22(2):71-74 de Oliveira EP, Burini RC: The impact of physical exercise on the gast...
Ngày tải lên: 11/08/2014, 07:21
báo cáo khoa học: " Safe using messages may not be enough to promote behaviour change amongst injecting drug users who are ambivalent or indifferent towards death" ppsx
... risk behaviours Interviewee behaviour regarding testing and risk behaviour around BBVs can be seen as possible indicators of the behaviours are able to engage in if they are not ambivalent towards ... they are more likely to hold indifferent attitudes towards their death [45] This was evident in those interviewees who reported being ambivalent towards life as m...
Ngày tải lên: 11/08/2014, 18:20
Báo cáo y học: "All motifs are not created equal: structural properties of transcription factor - dna interactions and the inference of sequence specificity" doc
... All Motifs are NOT Created Equal: Structural Properties of Transcription Factor – DNA Interactions and the Inference of Sequence Specificity Michael B Eisen Affiliations: ... bound to DNA had been determined by x-ray crystallography, and computed the number of contacts between each base in the bound DNA and the protein For each factor they a...
Ngày tải lên: 14/08/2014, 14:21