... though they may be seeing other specialists The internist has an important role in educating patients about the indications, benefits, risks, and limitations of genetic testing in the management of ... also influence the severity of infirmity, effect of treatment, and progression of disease The primary care clinician is now faced with the role of recognizing and co...
Ngày tải lên: 07/07/2014, 01:20
... the relative risk ranges from two- to fivefold, underscoring the importance of family history for these prevalent disorders Pending further advances in genetic testing, the key to assessing the ... individual will vary depending on the size of the pedigree, the number of unaffected relatives, and the types of diagnoses, as well as the ages of disease onset within...
Ngày tải lên: 07/07/2014, 01:20
Chapter 064. The Practice of Genetics in Clinical Medicine (Part 3) potx
... cancer, representing another confounding variable in the pedigree analysis Some of the aforementioned features of the family history are illustrated in Fig 64-1 In this example, the proband, a ... whether based on family history, characteristic physical findings, or biochemical testing Careful clinical assessment can define the phenotype, thereby preventing unnecessary t...
Ngày tải lên: 07/07/2014, 01:20
Chapter 064. The Practice of Genetics in Clinical Medicine (Part 4) potx
... established disease, genetic testing for susceptibility to chronic disease is being increasingly integrated into the practice of medicine In most cases, however, the discovery of disease-associated genes ... analysis of the gene of interest In addition, PCR enables genetic testing on minimal amounts of DNA extracted from a wide range of tissue sources including leuko...
Ngày tải lên: 07/07/2014, 01:20
Chapter 064. The Practice of Genetics in Clinical Medicine (Part 5) pptx
... of their personal likelihood of disease in preparing pretest educational strategies Often, patients harbor unwarranted fear or denial of their likelihood of genetic risk Genetic testing has the ... concern that testing during childhood violates a child's right to make an informed decision regarding testing upon reaching adulthood On the other hand, testing should be offered in...
Ngày tải lên: 07/07/2014, 01:20
Chapter 064. The Practice of Genetics in Clinical Medicine (Part 6) pot
... issues; Assist in determining the role of genetic testing for the individual and family; Ensure that the patient is aware of the indications, process, risks, benefits, and limitations of the various ... prevention Finally, patients should understand the natural history of the disease as well as the potential options for intervention, including screening, prevention,...
Ngày tải lên: 07/07/2014, 01:20
Chapter 064. The Practice of Genetics in Clinical Medicine (Part 7) pdf
... based testing for presymptomatic diagnosis of the disorder However, up to onethird of individuals who are homozygous for the HFE mutation not have evidence of iron overload Consequently, in the absence ... assessment of phenotypic expression awaits further studies In contrast to the issue of population screening, it is important to test and counsel other family members w...
Ngày tải lên: 07/07/2014, 01:20
Chapter 064. The Practice of Genetics in Clinical Medicine (Part 8) pot
... intensive clinical screening, as it remains very challenging to predict disease penetrance, expression, or clinical course Although genetic diagnosis of these and other disorders is only beginning ... used in the clinical setting, predictive testing holds the promise of allowing earlier and more targeted interventions that can reduce morbidity and mortality We can expect the...
Ngày tải lên: 07/07/2014, 01:20
Báo cáo y học: "Chlamydia trachomatis Infection of Human Trophoblast Alters Estrogen and Progesterone Biosynthesis: an insight into role of infection in pregnancy sequelae." doc
... status in trophoblast The efficacy of C trachomatis infection of trophoblast was assessed by (i) determining the capacity of C trachomatis to initiate productive and transferable infection in trophoblast ... 63-68 Kanai-Azuma M., Kanai Y. , Kurohmaru M., Tachi C., Yazaki K., and Hayashi Y Giant cells transformation of trophoblast cells in mice Endocrine J...
Ngày tải lên: 08/08/2014, 16:23
Báo cáo y học: "Curricula for teaching the content of clinical practice guidelines to family medicine and internal medicine residents in the US: a survey study" ppt
... analyses for the two specialties (family medicine and internal medicine) separately and combined We conducted regression analyses in order to identify factors that are associated with the characteristics ... conception and design: EAA, RM, MCW, AM, and HJS; acquisition of data: EAA, RM, AS, MCW, AM, and TR; analysis and interpretation of data: EAA, GHG, and H...
Ngày tải lên: 11/08/2014, 05:21
báo cáo khoa học: " Curricula for teaching the content of clinical practice guidelines to family medicine and internal medicine residents in the US: a survey study" pot
... conception and design: EAA, RM, MCW, AM, and HJS; acquisition of data: EAA, RM, AS, MCW, AM, and TR; analysis and interpretation of data: EAA, GHG, and HJS; drafting of manuscript: EAA; critical revision ... A, Vedavalli A, Schunemann HJ, Akl EA, Mustafa R, Slomka T, Alawneh A, et al.: An educational game for teaching clinical practice guidelines to Internal...
Ngày tải lên: 11/08/2014, 16:20
Báo cáo y học: "Identification of an endogenous retroviral envelope gene with fusogenic activity and placenta-specific expression in the rabbit: a new "syncytin" in a third order of mammals" ppt
... representation of a rabbit placenta (right) and haematoxylin and eosin staining of a day 12 placenta section (left) with the main layers of the placenta indicated (B) Higher magnification of the areas framed ... Structure and in situ hybridization forand eosin staining of a dayof day 12 rabbit placenta: (A) Schematic representation placenta bit placenta (right)...
Ngày tải lên: 12/08/2014, 23:22
An investigation into loss of meaning in the translation process as manifested in the vietnamese version of the world is flat by thomas l friedman
... and analyzed the cases of loss in meaning occurred during translation in English -Vietnamese translation of The World Is Flat They are the unavoidable 25 26 phenomena in the process of translation ... OF MEANING IN THE TRANSLATION PROCESS AS MANIFESTED IN THE VIETNAMESE VERSION OF THE WORLD IS FLAT BY THOMAS L FRI...
Ngày tải lên: 14/05/2016, 18:39
Opening the Curtain on Playwright Gender: An Integrated Economic Analysis of Discrimination in American Theater
... aspects of human capital theory and discrimination theory relevant to the playwriting industry A discussion of the literature on these two theories, and a range of sub-theories within them, will contextualize ... production In labor economics terms, these explanations can be separated into human capital explanations and discrimination explanations Human capital theory emphas...
Ngày tải lên: 12/12/2016, 20:38
Báo cáo lâm nghiệp: "Status of an indigenous agro-forestry system in changing climate: A case study of the middle Himalayan region of Tehri Garhwal, India" potx
... of India and spans 14 over an area of 53,485 km2 Of the total 8,479,562 human population of the state, 78% lives in rural areas The agriculture land in the hills of Uttarakhand is scattered and ... METHODS Study area The present study was carried out in the Hisriyakhal group of villages of Tehri Garhwal district in the Uttarakhand state of India...
Ngày tải lên: 07/08/2014, 10:21