... 5¢-d(GGATGTCCATATTA GGACAT)-3¢ reproduces the sequence of the SRF recognition element of the c- fos enhancer [2,27] The mutants SREGfos 5¢-d(GGATGTgCATATTAGGACAT)-3¢ and SREGGfos 5¢-d(GGATGTggATATTAGGACAT)-3¢ ... a restricted range of conformational space Thus, for the CArG box of SREGGfos, the rigid G) 4A)3 step inhibits (by mechanical locking) the local freedom brought about by the C) 4A)3 step in SREfos ... interactions of CArG boxes and accessory proteins [21,22] The core domain of the SRF (core-SRF) binds to the CArG box as a homodimer [7,23,24] The speci c core-SRF SREfos complex is characterized...