Method in biological oxidative stress

... synthase (NOS; EC 1.14.13.39), and the citrulline generated as a by-product can be recycled to arginine by successive actions of argininosuccinate synthetase (AS; EC 6.3.4.5) and argininosuccinate ... accidents and also during incidents involving anesthesia To understand the role of citrulline- NO cycle enzymes, GS and the oxidative status in anoxia and reperfusion...

Ngày tải lên: 26/10/2012, 09:07

... Discussion The main finding of this study is the identification of a metabolic gene switch from fatty acids to glucose in the murine female heart at baseline linked to enhanced mitochondrial respiratory ... al Metabolic gene switching in murine female heart function [8] Likewise, high fatty acid oxidation rates in the diabetic heart results in...

Ngày tải lên: 18/02/2014, 16:20

... Oxidative stress after status epilepticus in rats inefficiency of the electron-carrying components of the mitochondrial transport chain, monoamine degradation, xanthine oxidase reaction, ... ascertain whether ROS are involved in the pathogenesis of temporal lobe epilepsy 1309 Oxidative stress after status epilepticus in rats Experimental procedures R M Freit...

Ngày tải lên: 19/02/2014, 16:20

... Hsp105 enhances oxidative stress-induced apoptosis (Eur J Biochem 269) 4149 Fig Suppression of oxidative stress-induced apoptosis in F9 cells by a potent p38 inhibitor F9, V1, S3 and S23 cells were ... activation of p38 induced by oxidative stress, we further examined whether its activation is responsible for the induction of apoptosis in F9 cells usin...

Ngày tải lên: 21/02/2014, 03:20

... overweight, insulin resistance, and the development of metabolic syndrome [10,13,15] Although reports show that the function and expression of different adipose genes in white and brown adipose tissues ... has investigated the impact of ambient air pollutants simultaneously in various of adipose depots Therefore, the purpose of this study was to examine c...

Ngày tải lên: 06/03/2014, 19:20

... residing in both the inner and outer mitochondrial membrane, that is activated by mitochondrial Ca2+ overloading and other factors including oxidative stress [88,89] In neurons the presence of PTP in ... buffer the incoming calcium resulting in an abrupt, sustained and irreversible increase in [Ca2+]c, probably coincides with the cleavage of the exchanger (but see [1...

Ngày tải lên: 07/03/2014, 12:20

... thioredoxins were found In this study we examined the involvement of the peroxiredoxin Bcp2 in oxidative stress in the hyperthermophilic aerobic archaeon Sulfolobus solfataricus Furthermore, ... clarified in detail and could play a key role in the detoxification processes In this study we examined the role of Bcp2 in order to increase the knowledge...

Ngày tải lên: 07/03/2014, 12:20

... Cotton GhMPK2 is involved in multiple signaling pathways Results Expression of GhMPK2 was upregulated by oxidative stress and phytohormones To study the effect of oxidative stress and signaling ... Cotton GhMPK2 is involved in multiple signaling pathways A B D C E F Fig Overexpression of GhMPK2 confers increased tolerance to oxidative s...

Ngày tải lên: 14/03/2014, 23:20

... EhADH2, indicating the presence of two catalytically independent domains, the N-terminal domain, displaying ALDH activity, and the C-terminal domain, containing an iron-binding domain, which is involved ... buffer and incubated for h on ice, and the remaining EhPFOR activity was determined A control experiment was prepared with a sample diluted in N2-purged buffer, and incubated...

Ngày tải lên: 15/03/2014, 23:20

... robust Ca2+ burst, suggesting that, on exposure to the oxidant, internal stores are also mobilized In yeast, the vacuole is the main storage location for intracellular Ca2+, so the H2O2induced Ca2+ ... and internal sources To further characterize the Ca2+ response to exogenous H2O2, we examined whether the Ca2+ flux comes from an external or an internal source In t...

Ngày tải lên: 15/03/2014, 23:20

... Changes in blood carnitine and acylcarnitine profiles of very long- chain acyl-CoA dehydrogenasedeficient mice subjected to stress Eur J Clin Invest 34, 191–196 Bach AC & Babayan VK (1982) Medium -chain ... situations, longchain fatty acids cannot be oxidized, and accumulate in tissues as long- chain acyl-CoAs and acylcarnitines [5] However, despite the well-known mechanism o...

Ngày tải lên: 15/03/2014, 23:20

... whether diamide was also able to affect the thiol ⁄ disulfide balance of these organs, and whether cysteine efflux to the blood was paralleled by a change in the Cys concentration in other tissues ... maximum total cysteine accumulated in RBCs and plasma is plotted against the diamide dose administered We further evaluated the effect of diamide infusion on vari...

Ngày tải lên: 16/03/2014, 02:20

... any of the inhibitors of mitochondrial function (Fig 3) Similar results were obtained with 0.5 mm H2O2 alone or in association with the mitochondrial function inhibitors (not shown) Since it was ... expression of genes involved in yeast oxidative stress response: mitochondrial function contribution cTPxI participates of H2O2-mediated signaling processes, including reg...

Ngày tải lên: 16/03/2014, 14:20

... that mitochondria contribute to the induction of oxidative stress during ischemia ⁄ reperfusion in brain There is a growing body of information concerning the mechanism of ROS generation by the ... ADP inhibits opening of the mPTP by occupying binding sites located in the inner and outer mitochondrial membrane [39,40] The binding of ADP stabilizes...

Ngày tải lên: 16/03/2014, 22:20