... Thus, claudins 11 and 19 serve similar functions in myelin Contactin Located on the long arm of chromosome 12 in humans (12 q 1 1- q12) and on chromosome 15 in mice (15 F), the contactin gene gives ... ; cm Includes bibliographical references and index ISBN -1 3 : 97 8 -1 -4 05 1- 5 84 0-4 (hardback : alk paper) ISBN -1 0 : 1- 4 05 1- 5 84 0-9 (hardback : alk paper) Neuroi...
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... the clinical onset, a gadoliniumenhancing lesion (not at the site involved in the original clinical event) is needed; if no enhancing lesion is present, a follow-up scan with new T 2- or gadolinium-enhancing ... enhancing MRI lesions Chemokines form a chemo-attractant gradient that is perceived by T cells and assists their invasion into the CNS Chemokines, including interferon γ-induc...
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Neuroimmunology in Clinical Practice - part 3 pdf
... high-affinity interleukin-2 receptor, anti-CD25); alemtuzumab (anti-CD52, Campath 1H); rituximab (anti-CD20); anti-CD40L/-CD154 (IDEC- 131 ); anti-IL-12, anti-CD6; anti-CD3 (OKT3); anti-Vβ5.2/5 .3+ T cells; ... anti-CD4; integrin inhibitors Inhibitors of intracellular Lymphocyte-specific cytoplasmic protein – tyrosine kinase P56lck; zeta-associated activation, signaling and protein (ZAP )-7 0...
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Neuroimmunology in Clinical Practice - part 4 pot
... Progressive Efficacy Clinical Trial of Recombinant Interferon-beta-1a in MS (SPECTRIMS) Study Group 2001 Randomized controlled trial of interferon-beta-1a in secondary progressive MS: Clinical results ... Interferon beta-1b is effective in relapsing-remitting multiple sclerosis I clinical results of a multicenter, randomized, double-blind, placebo-controlled trial Neurology, 43 (4...
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Neuroimmunology in Clinical Practice - part 5 potx
... surface in acute in ammatory demyelinating polyneuropathy Ann Neurol, 39 (5) , 6 25 35 Hu, W., Dehme, T., Pirhonen, J., Hartung, H.P and Kieseier, B.C 2006 Interleukin 23 in acute in ammatory demyelination ... plasmapheresis in acute disseminated (postinfectious) encephalomyelitis J Clin Apheresis, 7(4), 173 –9 Sugita, K., Suzuki, N., Shimizu, N et al 1993 Involvement of cytokines i...
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Neuroimmunology in Clinical Practice - part 6 pdf
... demyelinating polyneuropathy A double-blind, sham-controlled, cross-over study Brain, 119, 1055– 66 Hahn, A.F., Bolton, C.F., Zochodne, D and Feasby, T.E 1996b Intravenous immunoglobulin treatment ... molecule BB-1, the ligands CTLA-4 and CD28 and their mRNAs in chronic in ammatory demyelinating polyneuropathy Brain, 123, 166 0 6 Mygland, A and Monstad, P 2001 Chronic polyneuropathies i...
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Neuroimmunology in Clinical Practice - part 7 pps
... T-helper cells by inhibiting calcineurin While a controlled, double-blind clinical trial has shown its effectiveness in MG (Tindell et al., 1993), significant side effects and drug interactions usually ... and interstitial lung disease Anti-Jo-1 antibodies are rarely found in CADM patients even if they have interstitial lung disease The other interesting finding in this review is that...
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Neuroimmunology in Clinical Practice - part 8 ppt
... ANNA-1,2,3; VGCC (P/Q>N-type); GAD65; Zic4; GluR1 AGNA-1; ANNA-1,2,3; PCA-2; Ma2; CRMP-5; VGCC (P/Q>N-type) Amphiphysin CRMP-5; ANNA-1; 2, PCA-2 CRMP-5; recoverin CRMP-5; VGCC; amphiphysin; ganglionic ... increase in intracellular free calcium and inhibited 125I-α-bungarotoxin binding in cells expressing α7nAChR The authors postulate that these antibodies may act by blocking the α7nAChR t...
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Neuroimmunology in Clinical Practice - part 9 pot
... solution using the same manufacturing method was licensed in 199 2 Solvent detergent treatment, including partitioning steps and incubation at low pH in the final container has been effective in the ... are involved in fine control of movement with behavioral and emotional processing (Alexander et al., 198 6; Bhatia and Marsden, 199 4; Brown et al., 199 9; Nakano, 2000; Rolls, 199 4) Le...
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Neuroimmunology in Clinical Practice - part 10 pps
... 230–1 innate immunity interferon-gamma internodal proteins 13–17 CD9 13 myelin-associated glycoprotein 13–14 myelin-associated oligodendrocyte basic protein 14–15 myelin basic protein 14 myelin ... oligodendrocyte basic protein 14–15 myelin basic protein 14 myelin lipids 19 myelin oligodendrocyte glycoprotein 15 myelin protein zero 15 myelin sheath 11, 12 myelin and T-lymphocyte protein (MAL)...
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Urological Emergencies in Clinical Practice - part 1 docx
... Emergency medicine I Title Nigel C 616 .6¢025 ISBN 18 5233 811 3 II Reynard, John III Cowan, Library of Congress Cataloging -in- Publication Data Hashim, Hashim Urological emergencies in clinical practice ... 1- 8 523 3-8 1 1- 3 Springer-Verlag London Berlin Heidelberg Springer-Verlag is part of Springer Science+Business Media, Inc springeronline.com © Springer-Verlag Londo...
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Urological Emergencies in Clinical Practice - part 2 potx
... 1983 ;28 6:1780–1783 Hastie KJ, Dickinson AJ, Ahmad R, Moisey CU Acute retention of urine: is trial without catheter justified? J R Coll Surg Edinb 1990; 35 :22 5 22 7 McNeill SA Does acute urinary ... lumbar disc prolapse: mid-term results of 22 patients and literature review Orthopedics 20 02; 25: 727 –731 Chapter Nontraumatic Renal Emergencies John Reynard ACUTE FLANK PAIN—URETERIC OR...
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Urological Emergencies in Clinical Practice - part 3 pot
... caused by gas-forming organisms (Fig 3. 13) It is characterised by fever NONTRAUMATIC RENAL EMERGENCIES 39 a FIGURE 3. 13 a: A case of emphysematous pyelonephritis on plain abdominal x-ray Note the ... of a stone in the kidney c: A right pyonephrosis on CT postcontrast administration 3 NONTRAUMATIC RENAL EMERGENCIES 37 b c FIGURE 3. 11 Continued 38 J REYNARD FIGURE 3. 12 A lef...
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Urological Emergencies in Clinical Practice - part 4 docx
... creatinine level is higher than that of serum, the fluid is urine (the creatinine level will be at least 300 mmol/L) Flank pain if the ureter has been ligated An abdominal mass, representing a urinoma ... acceleration/deceleration and no TRAUMATIC UROLOGICAL EMERGENCIES 57 shock, since the chances of a significant injury being found are 1 cm deep parenchymal laceration of cortex, no extrava...
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