... differences in apoE expression, there are no isoform-specific differences in levels of apoE in brain tissue from these TR APOE mice, even with elevated apoE2 plasma levels [45] We have also previously ... there are apoE isoform-specific differences in dendritic degeneration and recovery following activation of innate immune response by LPS Methods Materials LPS and RAP (receptor-associated protein) ... neuronal membranes and dendritic degeneration in the absence of febrile response, discernable tissue damage, adaptive immune cell infiltrate, or detectable neuron loss [3] We investigated changes in...