Corporate finance chapter 012 porfolio selection and diversification

... and leads to release of potassium (K+) and to synthesis of prostaglandins (PG) and bradykinin (BK) Prostaglandins increase the sensitivity of the terminal to bradykinin and other pain-producing ... activated (Fig 12 -2) An example is substance P, an 11amino-acid peptide Substance P is released from primary afferent nociceptors and has multiple biologic activities It is a potent vas...

Ngày tải lên: 06/07/2014, 08:20

... these circuits has links in the hypothalamus, midbrain, and medulla, and it selectively controls spinal pain-transmission neurons through a descending pathway (Fig 12 -4) Human brain imaging studies ... significant analgesic effect (placebo) On the other hand, many patients find even minor injuries (such as venipuncture) frightening and unbearable, and the expectation of pain has bee...

Ngày tải lên: 06/07/2014, 08:20

... class of compounds in the management of acute severe pain Ketorolac is sufficiently potent and rapid in onset to supplant opioids for many patients with acute severe headache and musculoskeletal pain.There ... dose-related, and there is great variability among patients in the doses that relieve pain and produce side effects Because of this, initiation of therapy requires titration t...

Ngày tải lên: 06/07/2014, 08:20

... degree of tolerance and physical dependence are likely with long-term use Therefore, before embarking on opioid therapy, other options should be explored, and the limitations and risks of opioids ... cardiac conduction delay, memory impairment, constipation, and urinary retention, are particularly problematic in elderly patients, and several are additive to the side effects of opioi...

Ngày tải lên: 06/07/2014, 08:20

... effective for many painful conditions, opioids are sedating, and their effect tends to lessen over time, leading to dose escalation and, occasionally, a worsening of pain due to physical dependence ... they are suffering and because only physicians can provide the medications required for pain relief A primary responsibility of all physicians is to minimize the physical and emotional d...

Ngày tải lên: 06/07/2014, 08:20

... small-diameter myelinated Adelta (Aδ) and the unmyelinated (C fiber) axons (Fig 12 -1) These fibers are present in nerves to the skin and to deep somatic and visceral structures Some tissues, ... These properties illustrate the duality of pain: it is both sensation and emotion When acute, pain is characteristically associated with behavioral arousal and a stress response consisti...

Ngày tải lên: 06/07/2014, 08:20

... hyperactivity should be sought in patients with posttraumatic pain and inflammation and no other obvious explanation Acute Pain: Treatment The ideal treatment for any pain is to remove the cause; ... 370) Although the pathophysiology of this condition is poorly understood, the pain and the signs of inflammation are rapidly relieved by blocking ... rapid and effective analgesia is...

Ngày tải lên: 06/07/2014, 08:20

... deposit? – – – Daily rate = 055 / 3 65 = 000 150 68493 Number of days = 3(3 65) = 10 95 FV = 15, 000 / (1.000 150 68493)10 95 = $12,718 .56 Copyright  2007 McGraw-Hill Australia Pty Ltd 55 1 ... Account:   – Daily rate = 052 5 / 3 65 = 0001438 356 2 FV = 100(1.0001438 356 2)3 65 = $1 05. 39 Second Account:   Semiannual rate = 053 9 / = 02 65 FV = 100(1.02 65) 2 = $1 05. 37 • You...

Ngày tải lên: 04/04/2016, 14:26

Ngày tải lên: 12/12/2013, 23:15

... Concepts and Skills • Understand the basics of call and put options • Be able to determine option payoffs and pricing bounds • Understand the major determinants of option value • Understand employee ... Valuing a Call Option Employee Stock Options Equity as a Call Option on the Firm’s Assets • Options and Capital Budgeting • Options and Corporate Securities 24- 3 Option T...

Ngày tải lên: 05/04/2015, 17:27

... KPMG Corporate Finance 11 3 11 5 Part Five: Mergers and Acquisitions 5 .1 Buying a Business David Houghton, TMG Corporate Finance 5.2 Thinking of Selling Your Business? Tony Sharp, KPMG Corporate Finance ... 225 13 7 14 5 15 3 16 3 18 1 18 7 19 7 203 215 235 245 Contents ix 6.4 HR Issues Arising from Acquisitions Judy Brown 6.5 Effective Environmental Due Diligence Willi...

Ngày tải lên: 14/12/2013, 15:15

... structured business finance provides is highly attractive to the corporate finance team involved in arranging the overall deal Structured business finance can provide a source of finance for the ... foreign trade finance and documentation, consult: Curmi, G (20 01): International Trade Finance and Documentation, in Reuvid, J (ed): A Handbook of World Trade, Kogan Page, London...

Ngày tải lên: 14/12/2013, 15:15

... 1 53 256 2000 Start-up Other early stage Financing stage Table 3. 3.1 Distribution of investment, 2000 100 19 16 46 42 – 35 13 22 2000 100 28 23 49 43 23 14 1999 7 03 175 528 2000 100 6 ,37 1 29 3, 546 ... 6 ,37 1 29 3, 546 20 3, 297 249 50 2,122 6,169 4,666 4,282 38 4 1,156 980 137 39 34 7 128 219 1999 3, 775 2,665 2,129 536 822 688 131 288 111 177 1998 Amount invested (£ mill...

Ngày tải lên: 14/12/2013, 15:15

... 350,000 262,500 87,500 600,000 240 ,000 360,000 950,000 502,500 44 7,500 The overall chargeable gain after taper relief is 44 7,500, which, using a CGT rate of 40 per cent, produces CGT of £179,000 ... for the full 40 per cent STR The overall calculation of chargeable gain is set out in Table 4. 3.1 Table 4. 3.1 Chargeable gain for CGT Gain A £ Chargeable gain Less taper relief 75% /40 %...

Ngày tải lên: 14/12/2013, 15:15

... 5. 1 Buying a Business David Houghton TMG Corporate Finance Introduction UK merger and acquisition activity totalled approximately ... as is reasonably possible, is secured during and after the deal 5. 2 Thinking of Selling Your Business? Tony Sharp KPMG Corporate Finance For many, the sale of a private company is the culmination ... with only the one opportunity to get it right Thi...

Ngày tải lên: 14/12/2013, 15:15