60733 roles in the family idioms and conversation
Báo cáo khoa học: Respective roles of the catalytic domains and C-terminal tail peptides in the oligomerization and secretory trafficking of human acetylcholinesterase and butyrylcholinesterase potx
... both the catalytic domain and the C-terminal t peptides contribute to the control of oligomerization and secretion, in a complex interplay Origin and significance of the difference between the t peptides ... C-terminal t peptides not in uence the catalytic activity of AChE and BChE We examined the possible in uence of the C-terminal peptides on the AChE and BChE activities by comparing the catalytic ... followed by small C-terminal t peptides of 40 and 41 residues, respectively In the present study, the catalytic domains are indicated by capital letters (A and B) and the C-terminal peptides by lower...
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Báo cáo khoa học: Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1 pot
... processing unit Fig E2 and E3BP domains and their binding interactions E2 subunit domains: L1, N-terminal lipoyl domain; L2, inner lipoyl domain; B, E1 binding domain; I, oligomer-forming, acetyl-transferase-catalyzing ... L2 In a second region at the other end of the L2 domain, mutation of glutamates 16 2, 17 9 and 18 2, and glutamine 18 1 greatly reduces binding Indeed, substitution of alanine or glutamine for Glu182 ... acetyl-transferase-catalyzing inner domain E3BP domains: L3, N-terminal lipoyl domain; B, E3 binding domain; I, inner domain which associates with the inner domain of E2 Dotted connections indicate binding interactions...
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Báo cáo khoa học: FLIP and MAPK play crucial roles in the MLN51-mediated hyperproliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis pdf
... followed by the blocking of FLS apoptosis FLIP upregulated by MLN51 plays a crucial role in the anti-apoptosis of MH7A cells We examined whether FLIP was involved in the antiapoptosis of MH7A cells ... affect MLN51 and FLIP induction in MH7A cells (Fig 5B), indicating that ERK is unlikely to be involved in the GM-CSF-mediated induction of MLN51 and FLIP in RA FLSs These data suggest that MAPK, particularly ... 3551 FLIP and MAPK in MLN51-mediated FLS hyperproliferation J.-E Ha et al A Fig Summary diagram showing the role of MLN51 in the GM-CSF-mediated proliferation of RA FLSs via MAPK activation and induction...
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Báo cáo khoa học: Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis pdf
... current opinions on how Bcl-2 and Bcl-xL are involved in the molecular events The crosstalk between the autophagy and apoptosis may redefine the roles of Bcl-2 and Bcl-xL in oncogenesis and tumor ... cancer treatment by modulating the two processes Bcl-2 and Bcl-xL in the apoptosis Bcl-2 and Bcl-xL inhibit apoptosis The Bcl-2 protein family was discovered by analysis of the t(14–18) chromosomal ... originally discovered in a yeast twohybrid screen as a Bcl-2- interacting protein, and was the first human protein shown to be indispensable for autophagy [44] The interaction between Beclin and...
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The chemical components of detergents and their roles in the washing process
... fabrics and on the washing machine’s heating elements - stabilise alkalinity at the correct level throughout the washing process thus giving good soil removal and enabling the other components of the ... present in the washing machine from previous washes, thus reactivating any remaining detergents and improving detergent performance No other single chemical offers all, or even most, of these different ... necessarily involves the inclusion of a number of complex, new chemicals and a complete restructuring on the detergent's formula, often with significant increase in other existing ingredients For each of...
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Báo cáo y học: "ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis" pdf
... Cal S, Obaya AJ, Llamazares M, Garabaya C, Quesada V, LopezOtin C: Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with ... surface involves C-terminal cleavage by glycosylphosphatidyl inositolanchored membrane type 4 -matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan ... indicating that other ADAMTS proteins might also be upregulated by inflammatory cytokines The induction of ADAMTS-4 mRNA in β-amyloid-treated rat astrocytes supports an inflammatory-associated...
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Báo cáo y học: "Bench-to-bedside review: Functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis" ppsx
... carboxyl terminus of peptides and proteins In the case of fibrin, removal of carboxyl-terminal lysine residues renders the fibrin less sensitive to lysis by decreasing the ability of plasminogen and ... Functional interrelationships between clotting and the innate immune response The close ancestral and functional linkage between clotting and inflammation is readily appreciated in study of human physiologic ... [7,15] Any injury to the exoskeleton of the crab immediately jeopardizes the integrity of the internal milieu of the organism Not only is there a real threat of loss of internal contents of the crab...
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CHARACTERISATION OF GLUTAMYL TRANSPEPTIDASE AND ELUCIDATING ITS ROLES IN THE PATHOGENESIS OF HELICOBACTER PYLORI
... recombinant proteins in E coli Raising and characterizing specific polyclonal and monoclonal antibodies against GGT Determining the subcellular localization of GGT in H pylori Investigating the ... Assessing the ability of GGT in inducing IL-8 generation in various cell types Analyzing GGT entry into host cells and its probable downstream effects Examining the role of GGT in vacuolation induction ... ability to maintain long-term colonization in the gastric mucosa of the mice compared to the wild type strain, indicating the importance of catalase in the chronic persistence of H pylori (Harris...
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Từ khóa: organisational structures and job roles in the interactive media industrychromium roles in the regulation of lean body mass and body weightdos compatibility sub mode in the intel486™ pentium® and p6 processor family and pentium® 4 processorshas attracted increasing attention as a component of amperometriclglutamate sensors used in the food industry and clinical biochemistry the precursor of lgoxhow to prevent applications listed in the registry run and runonce keys from startingthe role of energy in the body health and social carewalk in the light lyrics and chordsgirl in the mirror lyrics and chordswalk in the light chords and lyricsamerican imperialism in the late 19th and early 20th centuriesgold mine in the sky lyrics and chordsif we walk in the light lyrics and chordsthe role of energy in the industrial revolution and modern economic growthglobal defensive alliances in the join corona and composition of graphswalking in the sunshine lyrics and chordsNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015TÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ