Mobility is a key predictor of change in well being among older adults who experience falls evidence from the vancouver falls prevention clinic cohort

... the data ACCEPTED MANUSCRIPT Mobility predicts wellbeing among older fallers Mobility is a key predictor of changes in wellbeing among older fallers: Evidence from the Vancouver Falls Prevention ... MANUSCRIPT Mobility predicts wellbeing among older fallers We conducted a longitudinal analysis of data from a 12-month prospective cohort st...

Ngày tải lên: 25/08/2016, 22:07

... study is a prospective clinical investigation of the prognostic value of circulating Ang-2 as a biomarker in critically ill patients The results are that: critically ill patients are characterised ... be statistically significant at a 10% level in the univariate analysis and subjected to multivariate Cox regression analysis: lactate, APACHE II score, SOFA score and...

Ngày tải lên: 25/10/2012, 10:31

... years has led us to consider again this point: can the succession of short hypoxia and reoxygenation phases, typical of intermittent hypoxia, also stabilize HIF- 1a and activate HIF-1? In the absence ... hypoxia in cancer S Toffoli and C Michiels Fig Effects of intermittent hypoxia and chronic hypoxia on HIF- 1a stabilization and HIF-1 target gene transcri...

Ngày tải lên: 30/03/2014, 04:20

... multicellular organisms [15] There are four isoforms (A D) of mammalian MEF2, and they have high homology within the 56-amino-acid MADS box at their N-termini and within an adjacent 29 -amino-acid region ... as the MEF2 domain The MADS box is essential for DNA binding and dimerization, and the MEF2 domain plays an important role in DNA binding affinity as well as an indirect rol...

Ngày tải lên: 30/03/2014, 20:20

... primary blasts Haematologica 2008, 93:662-669 34 Sharma SV, Haber DA, Settleman J: Cell < /b> line-based platforms to < /b> evaluate the < /b> therapeutic efficacy of < /b> candidate anticancer agents Nat Rev Cancer < /b> ... Gautschi O, Mack PC, Davies AM, Lara PN, Gandara DR: Aurora < /b> kinase inhibitors: a < /b> new class of < /b> targeted drugs in < /b> cancer < /b> Clin Lung...

Ngày tải lên: 18/06/2014, 22:20

... inhibitors Conveniently, it is < /b> standard clinical practice to < /b> perform karyotyping on hematological < /b> cancer < /b> cells and chromosome < /b> number < /b> can serve as a < /b> resistance marker for patient response < /b> to < /b> GSK1070916 ... percentage of < /b> polyploidy in < /b> cell < /b> subpopulations For instance, the < /b> karyotype data for the < /b> T...

Ngày tải lên: 20/06/2014, 04:20

... motifs that are characteristic of RNA-binding proteins, and an alanine-rich carboxy-terminal sequence that could be involved in protein–protein interactions Interestingly, this alanine-rich sequence, ... Gld2 Rbm9 interaction (Fig 2B) However, the RRM-containing central domain of hRbm9 (amino acids 48–269) and amino acids 269–350 of hRbm9 are not able to mediate the binding These...

Ngày tải lên: 07/03/2014, 05:20

... impact on the crystallinity of untreated Avicel Multivariate statistical analysis of X-ray data The CrI of cellulose samples was also calculated by quantifying the contribution of amorphous cellulose ... such dramatic drops in the rate Constant crystallinity and decreased rates indicate surface changes on cellulose that start rapidly after the beginning of hyd...

Ngày tải lên: 15/03/2014, 10:20

... survival of critically ill HIV/AIDS patients In this study, we prospectively followed up HIV/AIDS critically ill patients to evaluate the key factors related to outcome, with emphasis on impact of ... sepsis is the main risk factor for hospital mortality in a cohort of HIV/AIDS critically ill patients Sepsis-related mortality was increased in both shortand l...

Ngày tải lên: 13/08/2014, 21:21

... GJ, Hammond SM: A microRNA polycistron as a potential human oncogene Nature 2005, 435:828-833 Hayashita Y, Osada H, Tatematsu Y, Yamada H, Yanagisawa K, Tomida S, Yatabe Y, Kawahara K, Sekido Y, ... HAS2 -A HDAC4 -A HDAC4-B HDAC4-C HDAC4-D HIF1 -A HIF 1A- B IRF1 -A KHDRBS1 -A KHDRBS1-B KPNA2 -A MAP3K8 -A MAP3K8-B MAPK9 -A MYCN -A MYCN-B NCOA3 -A NCOA3-B NCOA3-C NCOA3-D NR...

Ngày tải lên: 14/08/2014, 20:22

... unable to say at this stage (26 – 39%) Statistical modelling The final stage of analysis focuses on the modelling of intentions and working as a nurse The relationships between intentions expressed ... Figure Path model of job satisfaction, future intentions and nursing at 18 months and years Path model of job satisfaction, future intentions and nursing...

Ngày tải lên: 18/06/2014, 17:20

... that both the absolute value of respiratory system compliance on day and the decrease in respiratory system compliance between days and of mechanical ventilation for ALI are associated with increased ... adjusted odds ratio of death for selected variables on day 1, day and the change in each variable between day and day Day Δ Day ➔ Day Day...

Ngày tải lên: 12/08/2014, 13:22

... (L5D2), day last instar (L6D0), and day last instar (L6D1) larvae (Inset) DDC activity in integuments from the same larval stages a* , Significantly different from TH activity of L5D2 larval dorsal integument ... counter (Aloka LSC5100, Tokyo, Japan) Cloning and sequence analysis of TH cDNA Total RNA was isolated from integuments of day last instar larvae using TRIzol reagent (Gib...

Ngày tải lên: 16/03/2014, 11:20

... b-actin cDNA was also amplified using primers b-actin F (sense) (5¢-AGAAAATCTGGC ACCACACC-3¢) and b-actin R (antisense) (5¢-TAGCACAGCCTGGATAGCAA-3¢), and served as the internal control Melting-curve ... against Ets-1 raised against its N-terminal region and an antibody against Elk-1 raised against phosphorylated Ser383 present at the C-terminus of this protein Preincubation of nuclear pr...

Ngày tải lên: 29/03/2014, 09:20

... Kurokawa K, Ishii K, Yokoyama K, Han CG, Ohtsubo E, Nakayama K, Murata T, Tanaka M, Tobe T, Iida T, Takami H, Honda T, Sasakawa C, Ogasawara N, Yasunaga T, Kuhara S, Shiba T, Hattori M & Shinagawa ... species, then a plot of the natural logarithm of the protein absorption at 280 nm [ln (A2 80)] vs the square of the radial distance (r2) shows a linear T Kato et al correlation...

Ngày tải lên: 30/03/2014, 16:20