... of Ruk isoforms This hypothesis is currently under investigation The discovery of Ruk isoform ubiquitination in cells prompted us to investigate the importance of this modification, especially ... of Ruk isoforms (EE Ruk L, EE Ruk M and EE Ruk S) Transiently expressed Ruk isoforms were immunoprecipitated with anti-EE Ig and resolved by SDS/ PAGE Modification of Ruk by Ub...
Ngày tải lên: 17/03/2014, 23:20
... induced by lowering pH does not allow a tight interaction of G4–6 with G-actin Discussion The pH- dependence of the G2/G4–6 interface Activation of gelsolin by calcium and/or low pH has been found to ... general is not reduced by low pH It is possible therefore that in pH- activated gelsolin, the helical latch may be the last event to occur...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo Y học: The cytoplasmic C-terminus of the sulfonylurea receptor is important for KATP channel function but is not key for complex assembly or trafficking pdf
... complex The data reported here show that the cytoplasmic C-terminus of SUR1 has a key role in channel function but is not absolutely required for complex assembly or trafficking Our data support aspects ... DISCUSSION In this study we report a comprehensive study in a mammalian cell line of the effects of deletion of the SUR1 C-terminus on assembl...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo Y học: The C-terminal region of ammodytoxins is important but not sufficient for neurotoxicity pot
... perfectly match their theoretical values, assuming formation of all seven disulfide bonds in the sPLA2 molecule Influence of the mutations on the secondary structure and overall conformation of the ... toxicity of the construct; only the enzymatic activity on PtdCho–Triton X-100 mixed micelles increased twofold The increase in enzymatic activity of the N24F chimera was...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo y học: "Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells" ppsx
... important roles either during the < /b> initiation phase of < /b> arthritis < /b> or < /b> in < /b> the < /b> perpetuation and exacerbation of < /b> the < /b> disease after the < /b> onset, or < /b> they might simply maintain immunity to CII and perpetuate ... intravenously day after the < /b> antibody transfer As expected, injection of < /b> the < /b> antibodies < /b> alone was...
Ngày tải lên: 09/08/2014, 01:24
Báo cáo y học: " TGF β-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7" pps
... synovial lining is where TGF- β induces synovial fibrosis, by co-transfection with Smad7, the lining appeared to be less sensitive to TGF- β-induced fibrosis The reduction of TGF- β-induced fibrosis was ... deal of the TGF- β-induced synovial fibrosis Combining Smad7 and TGF- β resulted in a higher PG synthesis after IL-1 insult than did TGF- β alone This is...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "The World Trade Center Attack Disaster preparedness: health care is ready, but is the bureaucracy" pdf
... the World Trade Center disaster of 11 September 2001 They did not hesitate to place themselves in harm's way to rescue the innocent, and without their efforts many more would have perished They ... specific authority?) Following the earthquakes in Mexico City, the explosion in Oklahoma City, the World Trade Center attack, the floods in Houston, and the events in A...
Ngày tải lên: 12/08/2014, 18:21
Social media marketing is dead the way brands use it today
... becomes the next person’s ZMOT Content is the King! Only if You Treat it Like a King It s NOT about Technology It s NOT about Platforms It s NOT about Devices It s NOT about Social Media ... most established companies in the from the brilliant world, we work start-ups and with amazing clients challenging brands through to the biggest, best and most establi...
Ngày tải lên: 30/11/2015, 10:36
Đề tài NCKH: Tính triết lý trong sáng tạo hội họa thể hiện qua cách dùng bút
... trị, tài tác giả qua cách sử dụng bút, mực - Ý niệm, triết lý sống thể qua cách sử dụng bút sáng tạo nghệ thuật - Làm rõ ảnh hưởng qua lại nghệ thuật phương Đông phương Tây qua cách sử dụng bút ... ngoạn nhìn sắc bén tư duy, triết lý sáng tạo họa sĩ Thông qua đề tài, tác giả mong muốn đóng góp phần lý luận phương pháp thể bút, làm tiền đề c...
Ngày tải lên: 04/07/2013, 01:26
Besides increasing the number of universities,rasing the education quality is also urgent problem
... facilities Deputy of Ministy MOET said that qualification of lecturers must be up graded Besides increasing the number of universities,rasing the education quality is also urgent problem 7.Doctor ... school , teacher’s quality and new structure.he also hoped that the number of student drop-outs will minimising .Besides, the ministry also encouraged...
Ngày tải lên: 19/07/2013, 16:34
Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... exposure of liver cells to FFAs Interruption of TAG synthesis in conditions of excess availability of SFAs is the key point in the molecular mechanism of SFA-induced lipotoxicity It is suggested ... constitutes the initiating event in the process of lipotoxicity Stearate has to be activated in order to be toxic The first enzyme involved in me...
Ngày tải lên: 14/02/2014, 22:20