... point of view, but also in that the total synthesis of each molecule reflects the limits of the power of the art and science of organic synthesis at the time of the accomplishment. One of the most ... Dedicated to Professor E. J. Corey for his outstanding contributions to organic synthesis At the dawn of the twenty-first cen- tury, the state of the art and science of total synthesis is as healthy ... rewarding period in the history of total synthesis. 3.4. The 1990s Era The climactic productivity of the 1980s in total synthesis boded well for the future of the science, and the seeds were already...