Structure activity relationship studies on the factor XIIIa inhibitor tridegin
Structure activity relationship studies on the factor XIIIa inhibitor tridegin
... further investigation One example of the latter group is tridegin, a potent inhibitor of the blood coagulation factor XIIIa Since its first isolation from the salivary gland of the giant amazon ... disulfide formation or reduction on protein function plays a regulatory role 145,146 A classification of the three dimensional conformation of disulfide bonds on the basis of...
Ngày tải lên: 26/11/2015, 10:18
Mechanistic studies of anti malarial spiroindolones and synthesis and structure activity relationship studies of an inhibitor of dengue proliferation
... I MECHANISTIC STUDIES OF ANTI- MALARIAL SPIROINDOLONES AND II SYNTHESIS AND STRUCTURE- ACTIVITY RELATIONSHIP STUDIES OF AN INHIBITOR OF DENGUE PROLIFERATION YAP PEILING ... wish you all the best and may you stay healthy and live life to its fullest! VOLUME I: MECHANISTIC STUDIES OF ANTI- MALARIAL SPIROINDOLONES Table of Contents (Volume I)...
Ngày tải lên: 26/11/2015, 10:48
Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc
... between the base adenine (or hypoxanthine) and the diphospho-bridge, as they can be replaced by much simpler ether strands These ether strands mimic the distance between the nucleobase and the diphospho-bridge, ... Regulation of calcium signalling by the second messenger cyclic adenosine diphosphoribose (cADPR) Curr Mol Medical 4, 239–248 16 Guse AH (2004) Bioc...
Ngày tải lên: 20/02/2014, 01:20
Báo cáo y học: "Figuring out what works: a need for more and better studies on the relationship between ICU organization and outcomes" potx
... includes the training and organization of intensivists With a virtual absence of information relating ICU training with ICU outcomes, many questions remain unanswered Is there an optimal duration of ... Keller A, Tarlov AR, Ware JE: Variations in resource utilization among medical specialties and systems of care: results from the Medical Outcomes Study JAMA 1992, 267:1624-163...
Ngày tải lên: 13/08/2014, 20:21
Tài liệu Báo cáo khoa học: Comparative studies on the functional roles of N- and C-terminal regions of molluskan and vertebrate troponin-I pdf
... 6A,B) In the present study, we compared the functional roles of the N- and C-terminal regions of 4482 H Tanaka et al molluskan and vertebrate TnI and revealed for the first time that (a) the alternative ... of the troponin complex In molluskan muscles, the C-terminal region does not function and troponin regulates contraction only through the act...
Ngày tải lên: 20/02/2014, 01:20
Tài liệu Báo cáo Y học: Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2C-methyl-D -erythritol 2,4-cyclodiphosphate in plants docx
... group of Glu207 into phytoene (the main labeled component of the lipidsoluble fraction) is systematically diminished by the addition of increasing amounts of [1-3H ]2C-methyl-D -erythritol 4-phosphate ... Formation of 4-(cytidine 50 -diphospho)-2-C-methyl-D -erythritol from 2-C-methyl-D -erythritol 4-phosphate by 2-C-methyl-D -erythritol 4-phosphate cytidyltran...
Ngày tải lên: 22/02/2014, 07:20
Case Studies on the Effectiveness of State Financial Incentives for Renewable Energy pdf
... regions of the state On the other hand, only a small fraction of those claiming the tax credit take advantage of the low-interest loan Furthermore, the property-tax exemption complements the ... National Laboratory, Matthew Brown of the National Conference of State Legislatures, Jane Weissman of the Interstate Renewable Energy Council, Frederick Beck of...
Ngày tải lên: 06/03/2014, 19:20
Báo cáo khoa học: Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization pdf
... co-expressing dopamine D1 and D2 fusion proteins (D1 CFP and D2R1–YFP – genetic variant of dopamine D2 receptor) d Measured in cell co-expressing dopamine D1 and D2 fusion protein (D1 CFP and D2R2–YFP ... two dopamine D2 receptor fusion proteins (D2 CFP and D2 YFP) f Measured in cell co-expressing two dopamine D2 receptor fusion proteins (D2 CFP...
Ngày tải lên: 07/03/2014, 03:20
The effects of early social-emotional and relationship experience on the development of young orphanage children pot
... The Effects of Early Social-Emotional and Relationship Experience on the Development of Young Orphanage Children St Petersburg © 2009 Blackwell Publishing Ltd ISBN: 978-1-405-19599-7 The Effects ... of Early Social-Emotional and Relationship Experience on the Development of Young Orphanage Children St Petersburg © 2009 Blackwell Publ...
Ngày tải lên: 15/03/2014, 15:20
Báo cáo khoa học: Biosynthesis of isoprenoids – studies on the mechanism of 2C-methyl-D-erythritol-4-phosphate synthase pdf
... above, these initial conditions were rapidly conducive to steady conditions where and were present in very similar concentrations, and the rates of the forward reaction (conversion of to 3) and the ... Discussion The main part of the present study was a search, under conditions of maximal stringency, for fragment exchange that could be the hallmark of the hypothetical...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein Role of the 4¢-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein docx
... The chaotrope-induced unfolding was almost fully reversible in both forms of the protein Removal of the perturbation makes the protein regain its native form The unfolding reactions of both forms ... as the major and the minor forms of the holoACP structure, on the basis of their percentage contributions (65% and 35%, respectively) to the...
Ngày tải lên: 16/03/2014, 10:20
Báo cáo khoa học: Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferase Stability studies on the product-activated enzyme potx
... not only in the presence of xanthine and PRPP, but also on formation of the enzyme ⁄ hypoxanthine ⁄ PRPP ternary complex, conditions that represent those used for activation of the enzymes Pronounced ... activation was observed only upon incubation with PRPP and hypoxanthine, and not with guanine and xanthine, the other purine substrates of the enzyme Although no metal io...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: Studies on the regulatory properties of the pterin cofactor and dopamine bound at the active site of human phenylalanine hydroxylase pptx
... of phosphorylation rate seen at the concentration x of H4biopterin vo is the rate in the absence of H4biopterin and vmin is the rate at very high concentrations of H4biopterin The observed Hill ... H4biopterin, the oxidized cofactor H2biopterin and the catecholamine inhibitor dopamine From Fig 3A it is seen that on preincubation with saturating concentratio...
Ngày tải lên: 17/03/2014, 09:20
STUDIES ON THE ECOLOGY AND CONSERVATION OF BUTTERFLIES IN EUROPE: Vol. 1: General Concepts and Case Studies pptx
... Studies on the Ecology and Conservation of Butterflies in Europe STUDIES ON THE ECOLOGY AND CONSERVATION OF BUTTERFLIES IN EUROPE Vol 1: General Concepts and Case Studies Edited ... Nowicki, Studies on the Ecology and Conservation of in Europe Sofia – Moscow Vol 1: General Concepts and Case Studies, p 38 Altitudinal li...
Ngày tải lên: 23/03/2014, 01:20