The influence of the xin repeat containing proteins on the development of pressure induced cardiac hypertrophy in mice

... Xin repeat- containing proteins as part of the cardiac cytoskeleton As the function of the Xin repeat- containing proteins (XIRPs) in the heart will be in the center of this study, their role in ... proteins XIRP1 Xin repeat containing protein XIRP2 Xin repeat containing protein Introduction 1.1 The heart - an overview 1.1.1 Physiological...

Ngày tải lên: 26/11/2015, 10:06

... nasotihc eht rof )dnaloP ,nicezczS ,ytisrevinU erutlucirgA eneigyH laminA fo tnemtrapeD( zsimaR yzjolA rosseforP knaht ot hsiw srohtua ehT stnemgdelwonkcA sllec T edon hpmyl dna setyconelps B fo ... ihsiN ,S arumihsiN ,K arumihsiN 31 483-973 ,3 ,5891 eniccaV sgip aeniug dna ecim ni sevitavired nitihc fo ytivitca tnavujdA I amuzA ,S arukoT ,Y enoT ,F atamuN ,N ihsiN ,S arumihsiN ,K arumihsiN ....

Ngày tải lên: 07/08/2014, 18:21

... study and the interpretation of data, and helped to draft the manuscript MAD performed the statistical analysis and helped to draft the manuscript IG-A participated in the design of the study and ... effect of the erythrocyte sedimentation rate on the disease activity score, the use of this score represents a handicap for the evaluation of the eff...

Ngày tải lên: 09/08/2014, 13:22

... of PrPC-induced cell drug resistance in gastric cancer cells PI3K/Akt is involved in the activation of P-gp by PrPC in gastric cancer To further investigate the underlying mechanism of PI3K/Akt- mediated ... significantly increased The results indicate that inhibition of the PI3K/Akt signaling pathway may lead to inhibition of the MDR indu...

Ngày tải lên: 07/03/2014, 03:20

... levels of glial markers and the betaine transporter Glial activation is also involved in the pathogenesis of LPS-induced memory impairment; therefore, to understand the effects of betaine on these ... - 13 - Effects of acute administration of betaine on LPS-induced memory impairment We further examined whether a single administration of betaine i...

Ngày tải lên: 19/06/2014, 22:20

... Participation of MCP-induced protein in lipopolysaccharide preconditioninginduced ischemic stroke tolerance by regulating the expression of proinflammatory cytokines Jian Liang 1* , Jing ... 2003, 9: 11 80 -11 86 41 Wellen KE, Hotamisligil GS: Inflammation, stress, and diabetes J Clin Invest 2005, 11 5: 11 11- 111 9 25 Figure Legends Figure MCPIP1 mRNA and...

Ngày tải lên: 19/06/2014, 22:20

... neutrophils, lymphocytes, and eosinophils (b) Section from nasal septum, showing inflammatory infiltrates, fibrin deposition, and erosion of the cartilage Staining with hematoxylin and erythrosine Original ... ones The cytokine interleukin-10 (IL-10) has been in focus for many years in autoimmune arthritis and in other autoimmune diseases The human recombinant protein is...

Ngày tải lên: 09/08/2014, 01:24

... during the second month (weeks 4-6), the erythema and dry skin remain in areas previously dominated by the papulopustular eruption [9] Here, we report a case of lack of Cetuximab- induced skin rash ... possibility that the therapy may not be as beneficial in the absence of a skin reaction Our patient had a recurrence in a previously irradiated...

Ngày tải lên: 09/08/2014, 08:23

... Wu et al., Sodium valproate-induced congenital cardiac abnormalities in mice are associated with the inhibition of histone deacetylase Journal of Biomedical Science 2010, 17:16 Page of ... abnormalities in fetal hearts, which is likely associated with an inhibition of histone deacetylase without altering the transcription of this enzyme Co...

Ngày tải lên: 10/08/2014, 05:21

... evaluate the relationship between TLR-4-linked inflammatory reaction and intestinal gram-negative bacteria, colitis was induced by the oral administration of DSS for days and intrarectal injection of ... hydrogen peroxide, and hypochlorous acid, may be involved in the pathogenesis of IBD The colitic inducers, DSS and TNBS, increase malondialdehyde and 4hydrox...

Ngày tải lên: 11/08/2014, 08:22

... content of rat lungs Hydroxyproline content of rat lungs There was no significant difference in the hydroxyproline content of the four groups at days after instillation The hydroxyproline content of ... obviously by Lv-shCD36 Accordingly, CD36 may participate in the activation process of L-TGFβ1 in the early phase of the experimental silicosis Furthermore, si...

Ngày tải lên: 12/08/2014, 14:20

... significantly inhibited bleomycin-induced pulmonary fibrosis, suggesting that the mechanisms of action of EM703 against bleomycininduced pulmonary fibrosis in mice may involve not only anti-inflammatory ... significantly inhibited by EM703 (Figure 6) The mechanisms of inhibition by EM703 of bleomycininduced pulmonary fibrosis in mice may involve the i...

Ngày tải lên: 12/08/2014, 16:20

... demonstrate the presence of such opposite changes in the responsiveness of the airway and tissue compartments in the presence of oxygen toxicity Indeed, expression of the hyperoxia-induced changes in the ... in larger mammals [9,45] and in mice [46] Conclusion In summary, the results of the present study yield evidence of the involvement of ET-1...

Ngày tải lên: 12/08/2014, 16:20

... class, power and struggle have gone out the window in development discourse in many parts of the world, mainstream economics has jumped into development thinking and policy (including in South Africa ... working on South African development in the early years of the new democracy is coming to an end Despite success in some areas of economic and social ch...

Ngày tải lên: 29/03/2014, 05:20

... joint Finally, we studied the efficacy of microparticles containing DXM and SPIONs (referred to as complete microparticles) as an anti-inflammatory drug delivery system in an experimental model ... demonstrated by the preliminary study and considering the fact that they can incorporate more DXM and SPIONs than the 1-μm microparticles, we chose the 10-μm micropar...

Ngày tải lên: 09/08/2014, 14:20