Vitamin k dependent γ carboxylation in chronic kidney disease
Vitamin k dependent γ carboxylation in chronic kidney disease
... called vitamin K cycle (Figure 6) (43;44) DTdiaphorase/ VKOR Vitamin Vitamin KH 2K hydroquinone protein Vitamin K GGCX Warfarin GGCX carboxylated carboxylated protein protein VKOR VitVitamin K> O K ... contributes to γ- carboxylation of vitamin K dependent proteins like MGP, Osteocalcin (Ocn) or Gas6 The function of all vitamin K dependent proteins is mediated by binding of calcium to the γ- carboxylated ... 4.1.1.90) is an intrinsic membrane protein located in the endoplasmic reticulum and requires vitamin K as a cofactor (31) It utilizes both reduced vitamin K (KH2) and vitamin K with KH2 being the more...
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Bài giảng managing chronic heart failure patient in chronic kidney disease – BS trần hữu hiền
... reducing disease progression in both the heart and the kidney Arch Intern Med 2000 Mar 13;160(5):685-93 14 Angiotensin-converting enzyme inhibitors In patients with moderate or severe renal insufficiency, ... Angiotensin-converting enzyme inhibitors When the initiation of ACE inhibitor therapy leads to an increase in serum creatinine levels >30% above baseline ACE inhibitors should be discontinued, ... to individualized targets * KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease Diuretics Major clinical role in reducing fluid overload in patients...
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Báo cáo y học: "Hypoalbuminaemia – A Marker of Cardiovascular Disease in Patients with Chronic Kidney Disease Stages II - IV"
... CVD, malnutrion and inflammation in ESRD patients (25, 26) Hypoalbuminemia, a marker of malnutrition and underlying inflammation has come up as a powerful predictor of mortality in patients with ... C Inflammation enhances cardiovascular risk and mortality in hemodialysis patients Kidney Int 1999; 55: 64 8-6 58 27 Foley RN, Parfrey PS, Harnett JD, et al Hypoalbuminemia, cardiac morbidity, and ... of uremia: oxidative stress as a unifying concept of cardiovascular disease in uremia Kidney Int 2002; 62: 152 4-1 538 47 Stenvinkel P, Alvestrand A Inflammation in end-stage renal disease: sources,...
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Tài liệu Nutrition in Children with Chronic Kidney Disease pptx
... sheets: I Nutrition for Early Chronic Kidney Disease in Adults I Nutrition for Later Chronic Kidney Disease in Adults I Nutrition in Children with Chronic Kidney Disease For free single printed copies ... does not mean or Nutrition for Later Chronic Kidney imply that the Adults is unsatisfactory Disease in product I Nutrition in Children with Chronic Kidney Disease For free single printed copies of ... contact the National KidneyAbout the Nutrition for and Urologic Diseases Information Clearinghouse Chronic Kidney Disease Series The NIDDK Nutrition for Chronic Kidney Disease Series includes three...
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Insights from the Chronic Kidney Disease in Children (CKiD) Study potx
... of proteinuria with race, cause of chronic kidney disease, and glomerular filtration rate in chronic kidney disease in children study Clin J Am Soc Nephrol 4: 812– 819, 2009 16 Ardissino G, Testa ... SR, Parekh SR, Furth SL, Warady BA: Blood pressure in children with chronic kidney disease A report from the Chronic Kidney Disease in Children Study Hypertension 52: 631– 637, 2008 Mitsnefes M, ... calculation of power in longitudinal studies developed and published by the investigators at the data coordinating center (10) The putative exposures of interest in the CKiD cohort have included glomerular...
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Báo cáo y học: "Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease" pps
... peptide angiotensin- II Its inhibition reduces the pace of progression of the majority of chronic nephropathies [13,14] Among the candidate genes of the RAS, the ACE, and angiotensin II type receptor ... determination via FAGG (N-[3-(2furyl) acryloyl]-L-phenylalanylglycylglycine) method (Biochemical enterprise) The ACE presented in the serum catalyzes the hydrolysis of the FAGG; forming furyl acryloyl ... through reducing the production of angiotensin II with ACEI or by blocking the action of angiotensin II at the AT1R receptor level with A II- type receptor blockers (ARBs), is particularly effective...
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Báo cáo y học: " Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease" pot
... peptide angiotensin- II Its inhibition reduces the pace of progression of the majority of chronic nephropathies [13,14] Among the candidate genes of the RAS, the ACE, and angiotensin II type receptor ... determination via FAGG (N-[3-(2furyl) acryloyl]-L-phenylalanylglycylglycine) method (Biochemical enterprise) The ACE presented in the serum catalyzes the hydrolysis of the FAGG; forming furyl acryloyl ... through reducing the production of angiotensin II with ACEI or by blocking the action of angiotensin II at the AT1R receptor level with A II- type receptor blockers (ARBs), is particularly effective...
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Tài liệu CHRONIC KIDNEY DISEASE pdf
... of disease duration Although the distinction between acute, subacute, and chronic kidney disease (CKD) or failure is arbitrary, the differential diagnosis can frequently be narrowed if the disease ... recommended classification of chronic renal disease by stage: • Stage disease is defined by a normal GFR (>90 mL/min/1.73 m2) and persistent albuminuria • Stage disease is characterized by a ... present with kidney disease because of safety, ease of use, and the information provided Because obstruction is a readily reversible disorder, all patients who present with acute or chronic failure...
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Tài liệu Báo cáo khoa học: Gas6 and protein S Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily pptx
... The Gas6 Axl system S Hafizi and B Dahlback ¨ Gas6 and protein S, vitamin K-dependent ligands of the Axl RTK subfamily Fig Extracellular domain organizations of RTKs In this schematic are shown ... receptors, whereas Eph RTK possesses a fibronectin type III domain (Fig 1) The Axl RTKs participate in a signalling axis often referred to as the Gas6 Axl system, Gas6 being the ligand Since the ... that Sky and Mer could be involved in Table Affinities of Gas6 and protein S for Axl, Sky and Mer RTKs within and across different species (both rat Gas6 and human protein S were shown to stimulate...
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For Chronic Kidney Disease: Evaluation, Classification and Stratification doc
... of kidney disease This guideline, Chronic Kidney Disease: Evaluation, Classification and Stratification, will serve as the foundation for future guidelines by standardizing the definition and classification ... Factors for Adverse Outcomes of Chronic Kidney Disease 32 Stages of Chronic Kidney Disease 44 Definition of Chronic Kidney Disease 44 Definition and Stages of Chronic Kidney ... this document, please refer to the original source as follows: National Kidney Foundation K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification and Stratification...
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Chronic Kidney Disease Edited by Monika Göőz potx
... orders@intechweb.org Chronic Kidney Disease, Edited by Monika Göőz p cm ISBN 978-953-51-0171-0 Contents Preface IX Chapter ADAM Proteases as Novel Therapeutic Targets in Chronic Kidney Disease Monika Göőz Chapter ... Chronic Kidney Disease Edited by Monika Göőz Published by InTech Janeza Trdine 9, 51000 Rijeka, Croatia Copyright © 2012 InTech ... Monika Göőz Chapter Severity and Stages of Chronic Kidney Disease 13 Syed Ahmed and Gerard Lowder Chapter The New Kidney and Bone Disease: Chronic Kidney Disease – Mineral and Bone Disorder (CKD–MBD)...
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